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Marijuana
The Marijuana effects on each person depend on the user's experience,
as well as: how strong the marijuana is (how much THC it has); what
the user expects to happen; where (the place) the drug is used;
how it is taken; and whether the user is drinking alcohol or using
other drugs.

Some people feel nothing at all when they smoke marijuana. Some
users suffer bad effects from marijuana. They may suffer sudden
feelings of anxiety and have paranoid thoughts. This is more likely
to happen when a more potent variety of marijuana is used.
If someone is high on marijuana, he or she might seem dizzy and
have trouble walking; seem silly and giggly for no reason; have
a hard time remembering things that just happened; distorted perception;
trouble with thinking and problem-solving; and loss of coordination.
When the early effects fade, over a few hours, the user can become
very sleepy. 
Source: U.S. Department of Health and Human Services
NIH Publication Number 98-4037
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