Player Embed Code: Download Embed Share Centcom Protects and Promotes Nation’s Interests Defense.gov March 28, 2017 | 0:35 U.S. Central Command directs and enables military operations and activities with allies and partners to increase regional security and stability in support of enduring U.S. interests. Its area of responsibility includes 20 nations and stretches from Northeast Africa across the Middle East to Central and South Asia.