1 00:00:01,740 --> 00:00:03,796 Okay , Well , hello , everyone . And 2 00:00:03,796 --> 00:00:06,640 thank you for joining this update on 3 00:00:06,650 --> 00:00:10,270 Operation Warp Speed because of 4 00:00:10,840 --> 00:00:12,900 President Trump's founding and 5 00:00:12,900 --> 00:00:15,000 leadership of operation Warp speed . 6 00:00:15,740 --> 00:00:18,050 Even as we face daunting 7 00:00:18,270 --> 00:00:20,159 epidemiological trends around the 8 00:00:20,159 --> 00:00:22,860 country , we have reasons for optimism . 9 00:00:23,640 --> 00:00:25,640 With Monday's announcement from the 10 00:00:25,640 --> 00:00:27,807 Independent Data and Safety Monitoring 11 00:00:27,807 --> 00:00:30,470 Board for Madonna's candidate vaccine 12 00:00:30,850 --> 00:00:34,310 that it showed about 95% efficacy , we 13 00:00:34,310 --> 00:00:37,780 now have to safe and highly effective 14 00:00:37,790 --> 00:00:39,990 vaccines that could be authorized by 15 00:00:39,990 --> 00:00:42,046 the Food and Drug Administration and 16 00:00:42,046 --> 00:00:43,990 ready to distribute within weeks . 17 00:00:44,940 --> 00:00:47,050 Operation warp speed has accelerated 18 00:00:47,050 --> 00:00:49,080 the timelines for delivering on 19 00:00:49,080 --> 00:00:51,247 eventual safe and effective vaccine in 20 00:00:51,247 --> 00:00:53,960 a number of ways . We made development 21 00:00:53,960 --> 00:00:56,510 investments in five different vaccines 22 00:00:56,510 --> 00:00:59,220 and upfront pre purchase agreements 23 00:00:59,220 --> 00:01:02,160 with six vaccines driving drugmakers to 24 00:01:02,160 --> 00:01:04,490 begin manufacturing before they know 25 00:01:04,490 --> 00:01:06,379 whether they're products would be 26 00:01:06,379 --> 00:01:08,690 successful or not . We've worked 27 00:01:08,690 --> 00:01:10,690 closely with these manufacturers to 28 00:01:10,690 --> 00:01:12,912 ensure that they have what they need in 29 00:01:12,912 --> 00:01:15,134 the way of raw materials with operation 30 00:01:15,134 --> 00:01:17,357 work speed applying the same skills and 31 00:01:17,357 --> 00:01:19,579 that keep the U . S . Military supplied 32 00:01:19,579 --> 00:01:21,690 to ensure that there are no delays in 33 00:01:21,690 --> 00:01:24,350 vaccine production . Because of this 34 00:01:24,350 --> 00:01:26,700 work . By the end of December , we 35 00:01:26,700 --> 00:01:29,020 expect to have about 40 million doses 36 00:01:29,020 --> 00:01:31,410 of these two vaccines available for 37 00:01:31,410 --> 00:01:34,290 distribution pending FDA authorization 38 00:01:34,650 --> 00:01:36,872 enough to vaccinate about 20 million of 39 00:01:36,872 --> 00:01:39,160 our most vulnerable Americans . And 40 00:01:39,160 --> 00:01:41,382 production , of course , would continue 41 00:01:41,382 --> 00:01:43,438 to ramp up . After that . We've been 42 00:01:43,438 --> 00:01:45,604 laying the groundwork for distribution 43 00:01:45,604 --> 00:01:47,716 and administration for months . There 44 00:01:47,716 --> 00:01:50,090 are four major tasks necessary to get 45 00:01:50,090 --> 00:01:52,250 the manufactured product to Americans 46 00:01:52,250 --> 00:01:54,160 safely in order to save lives . 47 00:01:54,840 --> 00:01:57,370 Allocation , distribution 48 00:01:58,020 --> 00:02:01,330 administration , an ongoing monitoring 49 00:02:01,330 --> 00:02:04,440 and data work . We've led much of the 50 00:02:04,440 --> 00:02:06,273 groundwork for these efforts and 51 00:02:06,273 --> 00:02:08,840 covered the major costs we've paid for 52 00:02:08,840 --> 00:02:11,490 the vaccines . We've worked to ensure 53 00:02:11,490 --> 00:02:13,379 that administration costs will be 54 00:02:13,379 --> 00:02:15,379 covered by private insurers and the 55 00:02:15,379 --> 00:02:17,490 federal government through Medicare , 56 00:02:17,490 --> 00:02:19,712 Medicaid and our program to cover Covad 57 00:02:19,712 --> 00:02:21,546 19 costs for the uninsured so no 58 00:02:21,546 --> 00:02:23,546 American will face an out of pocket 59 00:02:23,546 --> 00:02:25,768 cost for getting a cove in 19 vaccine . 60 00:02:26,440 --> 00:02:28,800 We've procured ancillary supplies like 61 00:02:28,910 --> 00:02:30,910 needles and personal protective 62 00:02:30,910 --> 00:02:33,021 equipment and assemble them into kits 63 00:02:33,400 --> 00:02:35,289 that we will pair up with vaccine 64 00:02:35,289 --> 00:02:38,730 supplies as they're distributed . This 65 00:02:38,740 --> 00:02:41,020 overall task is a partnership between 66 00:02:41,020 --> 00:02:42,964 the federal government , including 67 00:02:42,964 --> 00:02:45,480 Operation Warp Speed and the CDC , and 68 00:02:45,480 --> 00:02:48,470 the 64 state , local and territorial 69 00:02:48,470 --> 00:02:50,430 public health jurisdictions at CDC 70 00:02:50,430 --> 00:02:53,130 works with on public immunization 71 00:02:53,140 --> 00:02:56,730 programs for allocation . The 500 is 72 00:02:56,730 --> 00:02:59,060 highly respected . Long Standing 73 00:02:59,180 --> 00:03:01,280 Advisory Committee on Immunization 74 00:03:01,280 --> 00:03:03,810 Practices will make recommendations to 75 00:03:03,810 --> 00:03:05,820 the 500 director about how to 76 00:03:05,820 --> 00:03:08,280 prioritize populations for distribution 77 00:03:08,940 --> 00:03:11,910 of initially scarce vaccine and will 78 00:03:11,910 --> 00:03:13,577 then be allocating vaccine to 79 00:03:13,577 --> 00:03:17,320 jurisdictions on a pro rata population 80 00:03:17,330 --> 00:03:20,380 basis . Then the federal government 81 00:03:20,380 --> 00:03:22,324 will use the contract we have with 82 00:03:22,324 --> 00:03:24,720 McKesson , one of the world's leading 83 00:03:24,730 --> 00:03:27,580 distributors of pharmaceutical and 84 00:03:27,580 --> 00:03:30,470 medical products , as well as a direct 85 00:03:30,480 --> 00:03:33,010 arrangement with Pfizer to ship the 86 00:03:33,010 --> 00:03:35,070 product from manufacturing sites toe 87 00:03:35,070 --> 00:03:37,430 where the jurisdictions decide it needs . 88 00:03:37,430 --> 00:03:39,920 Together , we've been working closely 89 00:03:39,920 --> 00:03:42,031 with those jurisdictions as they drop 90 00:03:42,031 --> 00:03:44,198 their plans for where vaccine needs to 91 00:03:44,198 --> 00:03:45,864 be shipped and how it will be 92 00:03:45,864 --> 00:03:47,920 administered , which they've already 93 00:03:47,920 --> 00:03:49,976 submitted to CDC for review and have 94 00:03:49,976 --> 00:03:52,170 received feedback on . We've done a 95 00:03:52,180 --> 00:03:54,236 great deal of work at HHS to support 96 00:03:54,236 --> 00:03:56,630 jurisdictions in these efforts . Last 97 00:03:56,630 --> 00:03:58,741 week , we reach nationwide agreements 98 00:03:58,741 --> 00:04:00,908 to allow administration of the vaccine 99 00:04:00,908 --> 00:04:02,852 by pharmacy chains and networks of 100 00:04:02,852 --> 00:04:05,019 independent pharmacies that cover more 101 00:04:05,019 --> 00:04:07,130 than 60% of the pharmacies across the 102 00:04:07,130 --> 00:04:09,352 country . Because of these agreements , 103 00:04:09,352 --> 00:04:11,574 states can have a ship product directly 104 00:04:11,574 --> 00:04:13,741 to these partners for administration , 105 00:04:14,240 --> 00:04:16,240 the vast majority of Americans live 106 00:04:16,240 --> 00:04:18,296 within five miles of a pharmacy , so 107 00:04:18,296 --> 00:04:20,351 vaccination and pharmacies is a huge 108 00:04:20,351 --> 00:04:22,184 piece of ensuring easy access to 109 00:04:22,184 --> 00:04:24,184 vaccines once they're authorized or 110 00:04:24,184 --> 00:04:26,018 approved and recommended for the 111 00:04:26,018 --> 00:04:28,350 general public . Using pharmacy 112 00:04:28,350 --> 00:04:30,550 networks allows us to expand access 113 00:04:30,720 --> 00:04:32,609 beyond just stand alone brick and 114 00:04:32,609 --> 00:04:34,831 mortar pharmacies because pharmacists , 115 00:04:34,980 --> 00:04:36,758 pharmacy and turns and pharmacy 116 00:04:36,758 --> 00:04:38,869 technicians also provide vaccinations 117 00:04:38,869 --> 00:04:40,990 in places like grocery stores . The 118 00:04:40,990 --> 00:04:43,212 ultimate goal here is to make getting a 119 00:04:43,212 --> 00:04:45,920 cove in 19 vaccine as convenient as 120 00:04:45,920 --> 00:04:49,340 getting a flu shot . This easy option 121 00:04:49,340 --> 00:04:51,562 complements the agreements we announced 122 00:04:51,562 --> 00:04:53,673 last month with CVS and Walgreens for 123 00:04:53,673 --> 00:04:55,896 them to offer vaccines in nursing homes 124 00:04:55,896 --> 00:04:58,062 and assisted living facilities , which 125 00:04:58,062 --> 00:05:00,050 presents special challenges . I am 126 00:05:00,050 --> 00:05:02,140 pleased to report that we have seen 127 00:05:02,140 --> 00:05:04,210 tremendous uptake of that option . 128 00:05:04,210 --> 00:05:07,280 Already , 99% of skilled nursing 129 00:05:07,280 --> 00:05:09,224 facilities across the country have 130 00:05:09,224 --> 00:05:12,070 signed up , and 100% of facilities in 131 00:05:12,070 --> 00:05:15,370 20 states are signed up . Finally , 132 00:05:15,740 --> 00:05:17,962 while any vaccine distributed will have 133 00:05:17,962 --> 00:05:20,073 already gone through months of safety 134 00:05:20,073 --> 00:05:21,962 testing , we're also working with 135 00:05:21,962 --> 00:05:24,018 jurisdictions to ensure that they're 136 00:05:24,018 --> 00:05:26,184 enrolled in the information technology 137 00:05:26,184 --> 00:05:28,351 infrastructure that we need to monitor 138 00:05:28,351 --> 00:05:30,890 for any potential safety issues . As I 139 00:05:30,890 --> 00:05:33,112 said at the start . We have reasons for 140 00:05:33,112 --> 00:05:36,410 optimism . Thanks , toa Incredible 141 00:05:36,740 --> 00:05:38,796 public servants working on operation 142 00:05:38,796 --> 00:05:42,730 warp speed elsewhere at HHS across 143 00:05:42,730 --> 00:05:44,841 the country . And thanks to President 144 00:05:44,841 --> 00:05:48,460 Trump's unwavering support of operation 145 00:05:48,460 --> 00:05:50,990 warp speed , we have such a bright 146 00:05:50,990 --> 00:05:53,560 future ahead of us . But at the same 147 00:05:53,560 --> 00:05:55,650 time that we have such good news on 148 00:05:55,650 --> 00:05:58,340 vaccines , we know we face daunting 149 00:05:58,340 --> 00:06:00,980 trends in the virus in most parts of 150 00:06:00,980 --> 00:06:04,450 the country , right now is not the time 151 00:06:04,450 --> 00:06:06,672 for anyone . Toe let their guard down . 152 00:06:07,540 --> 00:06:09,651 We continue to encourage Americans to 153 00:06:09,651 --> 00:06:12,360 follow the three W's . Wash your hands , 154 00:06:12,540 --> 00:06:14,710 watch your distance where your face 155 00:06:14,710 --> 00:06:16,710 coverings when you can't watch your 156 00:06:16,710 --> 00:06:18,821 distance and avoid settings where you 157 00:06:18,821 --> 00:06:20,766 can't do those things . As we look 158 00:06:20,766 --> 00:06:22,800 ahead to Thanksgiving next week , I 159 00:06:22,800 --> 00:06:24,911 urge Americans toe listen to guidance 160 00:06:24,911 --> 00:06:26,967 from the state and local governments 161 00:06:26,967 --> 00:06:29,170 and consult CDCs guidelines about how 162 00:06:29,170 --> 00:06:31,600 gatherings can be made as safe as 163 00:06:31,600 --> 00:06:34,200 possible . The safest way to celebrate 164 00:06:34,210 --> 00:06:36,510 Thanksgiving this year is at home with 165 00:06:36,510 --> 00:06:38,566 the people you live with and through 166 00:06:38,566 --> 00:06:40,530 virtual celebrations . Gathering 167 00:06:40,530 --> 00:06:42,697 indoors with people who aren't members 168 00:06:42,697 --> 00:06:44,641 of your household is a higher risk 169 00:06:44,641 --> 00:06:46,586 activity for spreading the virus . 170 00:06:47,040 --> 00:06:49,207 Please know that there is light at the 171 00:06:49,207 --> 00:06:51,151 end of the tunnel . Because of the 172 00:06:51,151 --> 00:06:53,620 sacrifices Americans have made and the 173 00:06:53,620 --> 00:06:56,210 hard work that so many have done , we 174 00:06:56,210 --> 00:06:58,099 will have the chance to celebrate 175 00:06:58,099 --> 00:07:00,210 holidays much more safely with family 176 00:07:00,210 --> 00:07:02,650 and friends . Not so far in the future . 177 00:07:03,340 --> 00:07:05,460 I now want to hand things over to Dr 178 00:07:05,460 --> 00:07:07,680 Slowey to discuss more about the 179 00:07:07,680 --> 00:07:09,791 current status of vaccine development 180 00:07:09,791 --> 00:07:11,736 and production and then to General 181 00:07:11,736 --> 00:07:14,300 Purna to discuss , in much more detail 182 00:07:14,650 --> 00:07:17,210 the distribution plans as they stand 183 00:07:17,210 --> 00:07:19,790 now , we anticipate having regular 184 00:07:19,790 --> 00:07:22,130 briefings of this kind for the media to 185 00:07:22,130 --> 00:07:24,670 ensure that you have full visibility 186 00:07:25,030 --> 00:07:27,060 into our vaccine and therapeutic 187 00:07:27,060 --> 00:07:30,070 programs , as well as our distribution 188 00:07:30,070 --> 00:07:32,600 planning in cooperation with the states 189 00:07:33,140 --> 00:07:34,973 doctors . Louis . Thank you , Mr 190 00:07:34,973 --> 00:07:38,080 Secretary . Hello , everybody . So we 191 00:07:38,080 --> 00:07:40,450 are , frankly very pleased with the 192 00:07:40,450 --> 00:07:43,280 progress made 10 months a little bit 193 00:07:43,280 --> 00:07:44,947 less than 10 months after the 194 00:07:44,947 --> 00:07:47,850 description of this new virus covered 195 00:07:47,850 --> 00:07:50,290 19 virus . In terms of vaccine 196 00:07:50,290 --> 00:07:52,457 development , we have to vaccines that 197 00:07:52,457 --> 00:07:56,150 have already shown 95% or so 198 00:07:56,150 --> 00:07:59,080 efficacy . We have tomb or vaccines 199 00:07:59,080 --> 00:08:01,790 that have shown that are recruiting 200 00:08:01,790 --> 00:08:04,990 phase three trials , with about 11,000 201 00:08:04,990 --> 00:08:06,990 subjects recruited in one and about 202 00:08:06,990 --> 00:08:09,101 8000 subjects recruiting in the other 203 00:08:09,101 --> 00:08:11,530 and tomb , or that should be starting 204 00:08:11,530 --> 00:08:13,752 their phase three trials in in the very 205 00:08:13,752 --> 00:08:17,620 near future . How come 10 months 206 00:08:17,620 --> 00:08:20,200 after describing this virus , we are 207 00:08:20,210 --> 00:08:22,880 able as an industry as , 208 00:08:22,880 --> 00:08:26,270 AH , government as academic ? 209 00:08:26,640 --> 00:08:30,120 How how come are we able to be so far 210 00:08:30,120 --> 00:08:32,480 along ? How how did how was this 211 00:08:32,480 --> 00:08:35,180 achieved ? What we've done was to 212 00:08:35,180 --> 00:08:38,110 leverage the decades of discovery and 213 00:08:38,110 --> 00:08:41,370 research that was done in identifying 214 00:08:41,570 --> 00:08:43,690 and optimizing platform technologies 215 00:08:43,690 --> 00:08:45,857 like cassette players that are able to 216 00:08:45,857 --> 00:08:48,100 play cassettes with different musics or 217 00:08:48,100 --> 00:08:50,433 make vaccines against different viruses . 218 00:08:50,690 --> 00:08:53,090 And we used a perfected set off 219 00:08:53,100 --> 00:08:56,100 cassette players to put in them the 220 00:08:56,100 --> 00:08:58,280 covet 19 information , and they played 221 00:08:58,290 --> 00:09:00,780 that music as well as we could have 222 00:09:00,790 --> 00:09:03,080 ever hoped , both in terms off their 223 00:09:03,270 --> 00:09:05,437 performance in the clinic and in terms 224 00:09:05,437 --> 00:09:07,548 off their capacity to be manufactured 225 00:09:08,040 --> 00:09:11,120 at large scale . We also went very fast 226 00:09:11,130 --> 00:09:14,210 because we took financial risks to 227 00:09:14,210 --> 00:09:16,270 invest in parallel in very large 228 00:09:16,270 --> 00:09:18,310 clinical trials as well as in 229 00:09:18,310 --> 00:09:20,477 manufacturing . Before we knew whether 230 00:09:20,477 --> 00:09:22,760 these vaccines would be effective or 231 00:09:22,760 --> 00:09:25,910 not , the trials are about 23 maybe 232 00:09:25,910 --> 00:09:28,010 even four times larger than what's 233 00:09:28,010 --> 00:09:30,160 required . Normally The reason we've 234 00:09:30,160 --> 00:09:32,500 done that was to be able to accrue 235 00:09:32,790 --> 00:09:35,640 enough cases faster by having more 236 00:09:35,640 --> 00:09:38,480 people into the trial . But the other 237 00:09:38,480 --> 00:09:40,647 reason we have done that is because by 238 00:09:40,647 --> 00:09:42,830 running larger trials were able to 239 00:09:42,830 --> 00:09:45,140 document the safety of these vaccines 240 00:09:45,150 --> 00:09:47,940 on larger population and have higher 241 00:09:47,940 --> 00:09:50,640 confidence in their safety before using 242 00:09:50,640 --> 00:09:54,310 to the population . Here we are , you 243 00:09:54,310 --> 00:09:56,940 know , a few months 78 months after the 244 00:09:56,940 --> 00:09:59,500 start of this process , with two 245 00:09:59,500 --> 00:10:01,800 vaccines that have achieved 95% 246 00:10:01,810 --> 00:10:04,760 efficacy , they will be shortly filed 247 00:10:04,770 --> 00:10:07,650 for emergency use authorization . And 248 00:10:07,650 --> 00:10:11,650 if approved , we have already started 249 00:10:11,660 --> 00:10:15,040 to stockpile vaccine . Those , as Mr 250 00:10:15,040 --> 00:10:18,210 Secretary has said to to the tune of 251 00:10:18,210 --> 00:10:20,154 about 40 million by the end of the 252 00:10:20,154 --> 00:10:22,400 month of December and equivalent or 253 00:10:22,400 --> 00:10:24,400 slightly higher number on a monthly 254 00:10:24,400 --> 00:10:26,640 basis , going forward to start 255 00:10:26,650 --> 00:10:29,050 immunizing the U . S . Population that 256 00:10:29,050 --> 00:10:32,760 need the vaccine . Now , let me say a 257 00:10:32,760 --> 00:10:34,960 few more words about the safety off 258 00:10:34,960 --> 00:10:38,420 these vaccines . As I said , we ran 259 00:10:38,420 --> 00:10:40,870 larger trials than required or than 260 00:10:40,870 --> 00:10:43,160 usual , and we have a pretty good 261 00:10:43,170 --> 00:10:45,550 understanding and description off what 262 00:10:45,550 --> 00:10:47,661 I would call the short term safety of 263 00:10:47,661 --> 00:10:50,570 this vaccine during the period off 264 00:10:50,580 --> 00:10:54,170 their clinical assessment . This period 265 00:10:54,170 --> 00:10:56,660 is shorter than usual . What we are 266 00:10:56,660 --> 00:10:59,060 doing is two things . First , we 267 00:10:59,060 --> 00:11:02,280 analyzed in the databases of the FDA 268 00:11:02,280 --> 00:11:06,210 over the last four decades , when in 269 00:11:06,210 --> 00:11:09,530 time to side effects of vaccines appear 270 00:11:09,840 --> 00:11:11,951 for vaccines that have been developed 271 00:11:11,951 --> 00:11:14,173 and there are tens and tens of vaccines 272 00:11:14,173 --> 00:11:16,229 that have been developed . And we've 273 00:11:16,229 --> 00:11:18,240 seen that over 90% of those side 274 00:11:18,240 --> 00:11:21,850 effects occur within the 40 days 275 00:11:21,860 --> 00:11:23,749 after completing the immunization 276 00:11:23,749 --> 00:11:26,020 schedule . This is the reason why the 277 00:11:26,020 --> 00:11:29,760 FDA said we have to have at least 60 278 00:11:29,760 --> 00:11:32,440 days of follow up on 50% of the study 279 00:11:32,440 --> 00:11:34,570 population in the clinical trials 280 00:11:34,570 --> 00:11:37,670 before we can consider approving this 281 00:11:37,670 --> 00:11:39,860 vaccine . So we cover , I would say , 282 00:11:40,160 --> 00:11:42,410 the overwhelming majority of potential 283 00:11:42,410 --> 00:11:45,090 side effects . We will understand the 284 00:11:45,090 --> 00:11:47,240 performance off the vaccine from that 285 00:11:47,240 --> 00:11:51,140 standpoint already . Now , Secondly , 286 00:11:51,140 --> 00:11:53,390 we are working with the FDA and the 287 00:11:53,400 --> 00:11:57,110 hundreds to set up together a very , 288 00:11:57,120 --> 00:11:59,790 very high performance active Pharma 289 00:11:59,790 --> 00:12:03,180 Cove vigilance system that resembles 290 00:12:03,190 --> 00:12:06,730 almost to the day the assessment that 291 00:12:06,730 --> 00:12:09,240 we do in clinical trials to look at the 292 00:12:09,240 --> 00:12:11,010 safety of the vaccines in the 293 00:12:11,010 --> 00:12:13,010 population . As the vaccine 294 00:12:13,010 --> 00:12:15,730 immunization is rolled out later in 295 00:12:15,730 --> 00:12:18,720 December . If the vaccines are approved 296 00:12:18,960 --> 00:12:21,190 and these data will be analyzed on a 297 00:12:21,190 --> 00:12:23,770 daily or by daily basis , and as soon 298 00:12:23,770 --> 00:12:25,870 as signals may appear , they will be 299 00:12:25,870 --> 00:12:28,320 analyzed exactly as in a clinical trial 300 00:12:28,700 --> 00:12:30,890 on conclusion Drone . And it is 301 00:12:30,890 --> 00:12:32,612 important that we were able to 302 00:12:32,612 --> 00:12:35,280 accelerate the vaccines to the extent 303 00:12:35,280 --> 00:12:37,750 we have done because , as you know , 304 00:12:37,750 --> 00:12:39,920 unfortunately , we have north of 305 00:12:39,920 --> 00:12:43,210 150,000 people infected every day and 306 00:12:43,210 --> 00:12:45,820 north of 1000 people dying every day 307 00:12:46,060 --> 00:12:48,360 and waiting two more months or four 308 00:12:48,360 --> 00:12:50,970 more months will count into the tens or 309 00:12:50,970 --> 00:12:53,303 the hundreds of thousands of MAWR debts . 310 00:12:53,540 --> 00:12:55,980 Ah , harm to the population that no 311 00:12:55,980 --> 00:12:59,920 vaccine ever would even approach in in 312 00:12:59,920 --> 00:13:02,700 decades or centuries . So we believe 313 00:13:02,700 --> 00:13:04,990 that these vaccines will have their 314 00:13:04,990 --> 00:13:06,990 safety and their efficacy very well 315 00:13:06,990 --> 00:13:09,240 documented to the point where we are 316 00:13:09,240 --> 00:13:11,540 today . We really look forward to the 317 00:13:11,540 --> 00:13:14,130 reviews with the F d . A . Who will 318 00:13:14,140 --> 00:13:17,220 independently with its vaccine review 319 00:13:17,220 --> 00:13:19,980 board , uh , potentially approved these 320 00:13:19,980 --> 00:13:22,202 vaccines and then the C . D . C and the 321 00:13:22,202 --> 00:13:24,369 A C I . P . As the secretary secretary 322 00:13:24,369 --> 00:13:26,850 said , I would recommend their 323 00:13:26,860 --> 00:13:30,190 utilization and then we look forward to 324 00:13:30,190 --> 00:13:33,030 the next two vaccines that we hope will 325 00:13:33,030 --> 00:13:35,910 be giving us data on their efficacy in 326 00:13:36,130 --> 00:13:38,170 the weeks to come . Maybe in early 327 00:13:38,170 --> 00:13:41,290 January , for one of them and for the 328 00:13:41,290 --> 00:13:44,680 other it could be in the next few weeks 329 00:13:44,690 --> 00:13:47,490 if data from trials running outside of 330 00:13:47,490 --> 00:13:50,930 the US read out or maybe slightly later . 331 00:13:50,930 --> 00:13:52,874 If trials in the U . S . Readout , 332 00:13:53,340 --> 00:13:55,451 thank you very much . And I will pass 333 00:13:55,451 --> 00:13:57,650 now to the co leader with me of the 334 00:13:57,650 --> 00:14:00,570 operations and alterna , Mr Secretary . 335 00:14:00,570 --> 00:14:02,681 And , of course , Dr Salah we , my co 336 00:14:02,681 --> 00:14:04,514 leader , uh , thank you for this 337 00:14:04,514 --> 00:14:07,160 opportunity to talk about and focus a 338 00:14:07,160 --> 00:14:10,170 little bit on distribution . Eso first 339 00:14:10,180 --> 00:14:12,890 just will say , this is it is a large 340 00:14:12,890 --> 00:14:16,450 task , but it's a task that we are up 341 00:14:16,460 --> 00:14:18,850 for on . We're gonna take a whole of 342 00:14:18,850 --> 00:14:20,890 America approach . That's why we're 343 00:14:20,890 --> 00:14:23,190 gonna be able to do this on . We've 344 00:14:23,190 --> 00:14:25,301 been working on this now for over six 345 00:14:25,301 --> 00:14:28,470 months since the announcement six 346 00:14:28,470 --> 00:14:30,581 months ago on May 15th , we literally 347 00:14:30,581 --> 00:14:34,390 started planning accordingly . On it 348 00:14:34,390 --> 00:14:36,780 is the foundation of our planning 349 00:14:36,790 --> 00:14:39,720 started with the great experts at the 350 00:14:39,720 --> 00:14:42,890 CDC on it's been extended to the 351 00:14:42,890 --> 00:14:45,580 jurisdiction , uh , planners , so that 352 00:14:45,580 --> 00:14:48,600 we have a great collaborative plan on 353 00:14:48,600 --> 00:14:51,170 how to execute this together . Right ? 354 00:14:51,180 --> 00:14:53,290 And as the secretary talked about 355 00:14:53,300 --> 00:14:56,210 earlier , uh , we have implemented 356 00:14:56,210 --> 00:14:59,890 several mechanisms to allow other 357 00:14:59,890 --> 00:15:03,570 organizations inside of America to 358 00:15:03,570 --> 00:15:06,560 enable execution . Not one , 359 00:15:07,140 --> 00:15:11,030 uh , source or one organization will be 360 00:15:11,030 --> 00:15:13,141 responsible . But it's the collective 361 00:15:13,141 --> 00:15:15,308 group of us . Uh , that will make this 362 00:15:15,308 --> 00:15:17,570 successful . So distribution of the 363 00:15:17,570 --> 00:15:19,710 vaccine will be based on fair and 364 00:15:19,720 --> 00:15:23,400 equitable availability of the vaccine 365 00:15:23,400 --> 00:15:25,990 pro rata to the population . So , in 366 00:15:25,990 --> 00:15:28,230 other words , population of the state 367 00:15:28,240 --> 00:15:31,280 against available vaccine will be 368 00:15:31,280 --> 00:15:34,580 distributed to each state . We 369 00:15:34,580 --> 00:15:37,250 are . Excuse me . We have been working 370 00:15:37,260 --> 00:15:39,730 these numbers with the States for a 371 00:15:39,730 --> 00:15:42,160 little while , and every week that goes 372 00:15:42,160 --> 00:15:44,960 by , we're able to create a tighter 373 00:15:44,960 --> 00:15:47,890 shot group of the actual numbers on the 374 00:15:47,890 --> 00:15:50,830 allocations that will be available to 375 00:15:50,830 --> 00:15:54,090 each state As we get going , uh , 376 00:15:54,100 --> 00:15:57,190 distribution will be by jurisdiction . 377 00:15:57,200 --> 00:16:00,280 A zai talked about . I use jurisdiction 378 00:16:00,280 --> 00:16:02,200 in states , you know , sometimes 379 00:16:02,210 --> 00:16:04,680 inappropriately . So let me define 380 00:16:04,680 --> 00:16:08,650 jurisdictions . 64 of them 50 states , 381 00:16:08,660 --> 00:16:12,040 eight territories and six metropolitan 382 00:16:12,040 --> 00:16:15,970 cities equal to 64 jurisdictions . 383 00:16:16,540 --> 00:16:18,810 We're doing extensive planning with 384 00:16:18,820 --> 00:16:22,000 each of these organizations so that we 385 00:16:22,000 --> 00:16:25,600 implement their plan , right ? So they 386 00:16:25,600 --> 00:16:27,490 will figure out where we want the 387 00:16:27,490 --> 00:16:29,450 vaccine to be distributed to and 388 00:16:29,450 --> 00:16:31,450 administered . And that's where the 389 00:16:31,450 --> 00:16:34,400 vaccine will be distributed accordingly . 390 00:16:34,410 --> 00:16:37,880 So we wanna emphasize following , Um , 391 00:16:37,890 --> 00:16:41,750 of course , FDA guidelines . C D C . A . 392 00:16:41,750 --> 00:16:45,220 Sip guidelines . The the governors and 393 00:16:45,220 --> 00:16:48,820 the states . We'll figure out the plan , 394 00:16:48,820 --> 00:16:50,540 and we're ready to execute in 395 00:16:50,540 --> 00:16:53,390 collaboration with their plan . Aziz , 396 00:16:53,390 --> 00:16:55,570 we've been working on for six months 397 00:16:55,940 --> 00:16:58,740 doing numerous tabletop exercises and 398 00:16:58,740 --> 00:17:00,570 now extended it in tow . Actual 399 00:17:00,570 --> 00:17:03,560 rehearsals of how to move the product 400 00:17:03,750 --> 00:17:05,472 from Phil finished sites . The 401 00:17:05,472 --> 00:17:08,040 distribution centers down toe , actual 402 00:17:08,050 --> 00:17:11,720 administration sites . We 403 00:17:11,730 --> 00:17:14,370 are making sure , as I said , that it's 404 00:17:14,370 --> 00:17:16,481 a whole of American approach , So let 405 00:17:16,481 --> 00:17:18,703 me pull the string on that a little bit 406 00:17:18,703 --> 00:17:20,926 for you . So clearly here in Health and 407 00:17:20,926 --> 00:17:22,870 Human Services , the C D . C . The 408 00:17:22,870 --> 00:17:25,450 cornerstone our experts that know how 409 00:17:25,450 --> 00:17:28,780 to distribute vaccine A Z they do every 410 00:17:28,780 --> 00:17:31,980 year annually for influenza , as 411 00:17:31,980 --> 00:17:34,800 they've done for H one n one , etcetera . 412 00:17:34,810 --> 00:17:38,070 Very talented group of people who know 413 00:17:38,080 --> 00:17:40,440 all the technical aspects and all the 414 00:17:40,440 --> 00:17:42,496 requirements that are needed to make 415 00:17:42,496 --> 00:17:46,410 sure that the vaccine once , uh once we 416 00:17:46,410 --> 00:17:48,240 have it still finished , we can 417 00:17:48,240 --> 00:17:50,840 distribute in a safe and effective way . 418 00:17:50,850 --> 00:17:52,683 The second step , as I mentioned 419 00:17:52,683 --> 00:17:55,600 earlier , is the 100% collaboration 420 00:17:55,600 --> 00:17:57,990 with the jurisdictions , making sure 421 00:17:57,990 --> 00:18:00,350 that we are integrated and synchronized 422 00:18:00,360 --> 00:18:03,580 and ready to implement their plan for 423 00:18:03,580 --> 00:18:07,420 way . They want to , uh , execute 424 00:18:07,430 --> 00:18:09,652 immunization down at the administration 425 00:18:09,652 --> 00:18:12,870 sites . Aziz they define it on . We're 426 00:18:12,870 --> 00:18:14,870 ready to do that because we've been 427 00:18:14,870 --> 00:18:16,926 working together for quite a while . 428 00:18:16,926 --> 00:18:18,990 CDC published a playbook back in 429 00:18:18,990 --> 00:18:21,500 September on the jurisdictions have 430 00:18:21,500 --> 00:18:23,389 been going through the playbook , 431 00:18:23,389 --> 00:18:24,944 filling it out . We've been 432 00:18:24,944 --> 00:18:27,056 collaborating on . We've been working 433 00:18:27,056 --> 00:18:29,167 the plan and the nuances to make sure 434 00:18:29,167 --> 00:18:31,980 that every detail is covered . Second , 435 00:18:31,990 --> 00:18:34,610 we're working with commercial industry . 436 00:18:34,690 --> 00:18:37,800 The experts in this field those that 437 00:18:37,800 --> 00:18:41,260 know how to produce , store , 438 00:18:41,270 --> 00:18:44,110 distribute and administer the vaccine 439 00:18:44,120 --> 00:18:46,670 accordingly . They do this every day . 440 00:18:46,680 --> 00:18:48,900 This is the United States of America . 441 00:18:48,910 --> 00:18:51,220 This is not new to us . And so 442 00:18:51,220 --> 00:18:53,276 organizations , of course , starting 443 00:18:53,276 --> 00:18:55,520 with Visor and Madonna , right ? Who 444 00:18:55,520 --> 00:18:59,300 know how Thio produce Phil finish and 445 00:18:59,300 --> 00:19:02,090 then begin distribution of the vaccine , 446 00:19:02,100 --> 00:19:04,470 right ? It's there . It's there , uh , 447 00:19:04,480 --> 00:19:06,900 core competency . Then we're working 448 00:19:06,900 --> 00:19:10,390 with McKesson , a large , very large 449 00:19:10,390 --> 00:19:13,520 distribution , uh , company that knows 450 00:19:13,520 --> 00:19:16,220 how to produce or distribute vaccine 451 00:19:16,230 --> 00:19:18,920 throughout the entire country , and 452 00:19:18,920 --> 00:19:21,370 I'll talk about that in a minute on 453 00:19:21,370 --> 00:19:23,650 then , as the secretary mentioned , we 454 00:19:23,650 --> 00:19:26,550 have collaborated with farmers such as , 455 00:19:26,560 --> 00:19:30,200 uh , CVS and Walgreens , right ? And so 456 00:19:30,200 --> 00:19:33,190 that we have already laid out plans and 457 00:19:33,200 --> 00:19:36,150 coordinated , uh , memorandum of 458 00:19:36,150 --> 00:19:37,872 agreement to ensure that we're 459 00:19:37,872 --> 00:19:40,500 executing , uh , the right way in 460 00:19:40,500 --> 00:19:43,270 accordance with the jurisdiction plans 461 00:19:43,540 --> 00:19:45,760 a zey direct will execute . So we're 462 00:19:45,760 --> 00:19:48,093 bringing this whole of America approach , 463 00:19:48,100 --> 00:19:51,900 uh , from government to industry on , 464 00:19:51,900 --> 00:19:53,789 we're bringing it all together to 465 00:19:53,789 --> 00:19:56,011 ensure that safe and effective vaccines 466 00:19:56,011 --> 00:19:58,233 are delivered to the American people in 467 00:19:58,233 --> 00:20:00,344 a timely manner . The time associated 468 00:20:00,344 --> 00:20:02,410 with delivery . We will begin 469 00:20:02,410 --> 00:20:05,530 distribution of the vaccine within 24 470 00:20:05,530 --> 00:20:08,940 hours after emergency use authorization 471 00:20:08,950 --> 00:20:11,300 is approved , right ? And on Lee , 472 00:20:11,300 --> 00:20:14,080 after the science has determined on 473 00:20:14,080 --> 00:20:16,690 approved it accordingly . Then we are 474 00:20:16,690 --> 00:20:19,470 poised and ready to begin distribution . 475 00:20:19,840 --> 00:20:23,260 Distribution will occur , uh , from 476 00:20:23,270 --> 00:20:26,730 our fill finished sites , and we'll go 477 00:20:26,730 --> 00:20:30,070 toe all 64 jurisdictions , uh , that 478 00:20:30,070 --> 00:20:32,126 we're responsible to ensure they get 479 00:20:32,126 --> 00:20:34,840 vaccine for within 24 hours . So 480 00:20:34,850 --> 00:20:36,940 everybody , every jurisdiction will 481 00:20:36,940 --> 00:20:39,510 have access immediately upon the 482 00:20:39,510 --> 00:20:42,000 initial push of vaccine , which is the 483 00:20:42,000 --> 00:20:43,722 quantities of vaccine that are 484 00:20:43,722 --> 00:20:46,320 available upon the emergency use 485 00:20:46,320 --> 00:20:48,810 authorization . Then we will begin a 486 00:20:48,810 --> 00:20:51,480 weekly cadence of delivery of vaccine . 487 00:20:51,800 --> 00:20:54,480 As vaccine comes off the shelf as it 488 00:20:54,480 --> 00:20:56,480 has been approved and available for 489 00:20:56,480 --> 00:20:59,480 distribution , we will distribute it to 490 00:20:59,480 --> 00:21:03,150 64 jurisdictions . So initial push 491 00:21:03,160 --> 00:21:05,760 and then continuous cadence of delivery 492 00:21:05,760 --> 00:21:08,790 of vaccine to ensure that we rapidly 493 00:21:08,790 --> 00:21:12,170 expand the availability to the entire 494 00:21:12,180 --> 00:21:14,680 country . Uh , simultaneously . 495 00:21:15,940 --> 00:21:19,860 We are working with jurisdictions to do 496 00:21:19,860 --> 00:21:22,027 several things , though , that we need 497 00:21:22,027 --> 00:21:24,193 to make sure that we get done . Aziz , 498 00:21:24,193 --> 00:21:28,070 we get closer . Thio Final approval a t 499 00:21:28,070 --> 00:21:31,100 u a by the FDA three things that we're 500 00:21:31,100 --> 00:21:33,267 working with the jurisdictions that we 501 00:21:33,267 --> 00:21:35,267 need to have . First , we must have 502 00:21:35,267 --> 00:21:38,800 jurisdictions . Um uh , create good , 503 00:21:38,800 --> 00:21:42,270 solid , expansive provider enrollment , 504 00:21:42,280 --> 00:21:45,190 right , as many organizations as they 505 00:21:45,190 --> 00:21:48,230 want need to be enrolled so that we can 506 00:21:48,230 --> 00:21:50,860 expand distribution rapidly to the 507 00:21:50,860 --> 00:21:53,280 quantities of vaccine that's available 508 00:21:53,640 --> 00:21:56,560 on Lee to providers that are enrolled . 509 00:21:56,570 --> 00:21:59,140 Can we distribute to so they can limit 510 00:21:59,140 --> 00:22:01,084 it to a certain amount or they can 511 00:22:01,084 --> 00:22:03,210 expand it so that we can sure that 512 00:22:03,210 --> 00:22:06,240 we're covering the entire country ? A 513 00:22:06,240 --> 00:22:08,590 secretary alluded to in his comments . 514 00:22:08,600 --> 00:22:11,370 Very key point we have made significant 515 00:22:11,370 --> 00:22:14,220 progress in this area . We're just 516 00:22:14,220 --> 00:22:17,050 counting the each is of provider 517 00:22:17,050 --> 00:22:19,272 enrollments that we need to get done as 518 00:22:19,272 --> 00:22:21,450 we get closer and closer to final 519 00:22:21,450 --> 00:22:24,160 distribution day . Second , we must 520 00:22:24,160 --> 00:22:27,310 have the States go through and sign 521 00:22:27,310 --> 00:22:29,660 your data use agreements . This is 522 00:22:29,660 --> 00:22:31,930 incredibly important , right ? For the 523 00:22:31,930 --> 00:22:34,550 new vaccine going out to the American 524 00:22:34,550 --> 00:22:37,740 people first , we must be able to see 525 00:22:37,750 --> 00:22:40,730 who got there first dose where they got 526 00:22:40,730 --> 00:22:43,320 their first dose . And what vaccine did 527 00:22:43,320 --> 00:22:45,710 they receive is their first dose ? Why ? 528 00:22:45,720 --> 00:22:48,120 Because we must ensure that we could do 529 00:22:48,120 --> 00:22:50,610 the same for the second dose of each 530 00:22:50,610 --> 00:22:53,510 vaccine that we're sending out . The 531 00:22:53,520 --> 00:22:55,870 second thing and really important is we 532 00:22:55,870 --> 00:22:59,430 wanna make sure that we have a good , 533 00:22:59,440 --> 00:23:01,770 consistent flow of vaccine out to the 534 00:23:01,770 --> 00:23:04,330 American people . And so our ability to 535 00:23:04,330 --> 00:23:06,580 track the uptake , the actual 536 00:23:06,580 --> 00:23:09,420 administration of the shot in an arm is 537 00:23:09,420 --> 00:23:12,470 gonna be essential to us making sure we 538 00:23:12,470 --> 00:23:14,960 did deliver vaccine on a continuous 539 00:23:15,240 --> 00:23:18,580 basis . So really important . The third 540 00:23:18,580 --> 00:23:21,070 thing , I would , uh , keep the 541 00:23:21,080 --> 00:23:23,670 jurisdictions working on . Is there 542 00:23:23,670 --> 00:23:26,010 actual rehearsals in the execution of 543 00:23:26,010 --> 00:23:28,380 the plan ? We conduct tabletop 544 00:23:28,380 --> 00:23:31,540 exercises at this level right where 545 00:23:31,550 --> 00:23:35,380 a lot of the all of 546 00:23:35,390 --> 00:23:37,940 government and industry and 547 00:23:37,940 --> 00:23:40,430 jurisdictions participate , but then 548 00:23:40,430 --> 00:23:42,610 were expanded . It now toe actual 549 00:23:42,620 --> 00:23:46,000 execution down at the tactical level 550 00:23:46,010 --> 00:23:49,230 or down in the local cities . How do we 551 00:23:49,230 --> 00:23:52,660 work ? Uh , distribution of vaccine 552 00:23:52,840 --> 00:23:56,170 through the CVS , Walgreens , etcetera 553 00:23:56,240 --> 00:23:58,880 at the hospital . How does it actually 554 00:23:58,880 --> 00:24:01,910 get received , unloaded , stored and 555 00:24:01,910 --> 00:24:04,440 then administered eyes ? The rehearsals 556 00:24:04,440 --> 00:24:07,010 were working . I continually , um , 557 00:24:07,020 --> 00:24:08,940 emphasize this when I talk to 558 00:24:08,940 --> 00:24:12,460 jurisdictions . It is a great mechanism 559 00:24:12,470 --> 00:24:15,080 to check and double check to make sure 560 00:24:15,080 --> 00:24:17,920 everything is in place . What we're 561 00:24:17,920 --> 00:24:21,640 doing to make sure that that we already 562 00:24:21,650 --> 00:24:23,630 at this level after working these 563 00:24:23,630 --> 00:24:26,370 details for the last six months a Z 564 00:24:26,370 --> 00:24:28,537 I've told the team to things . We must 565 00:24:28,537 --> 00:24:31,700 have one upon emergency use 566 00:24:31,700 --> 00:24:34,470 authorization . All of America must 567 00:24:34,470 --> 00:24:36,830 receive vaccine within 24 hours . As I 568 00:24:36,830 --> 00:24:38,900 said , I think this is incredibly 569 00:24:38,900 --> 00:24:41,160 important , fair and equitable 570 00:24:41,160 --> 00:24:43,740 distribution of the vaccine throughout 571 00:24:43,740 --> 00:24:46,400 the country . Simultaneously , there is 572 00:24:46,400 --> 00:24:48,770 no haves and have nots . Uh , it is an 573 00:24:48,780 --> 00:24:51,680 equitable distribution . Uh , and we 574 00:24:51,680 --> 00:24:53,902 are driving hard to make sure that that 575 00:24:53,902 --> 00:24:56,124 happens . The second thing that we want 576 00:24:56,124 --> 00:24:58,840 to do is make sure that the cadence of 577 00:24:58,840 --> 00:25:01,100 vaccine delivery following the first 578 00:25:01,100 --> 00:25:04,860 push is routine so that states slash 579 00:25:04,860 --> 00:25:07,950 jurisdictions can plan for it on 580 00:25:07,950 --> 00:25:10,780 account and develop execution of the 581 00:25:10,780 --> 00:25:13,550 administration and a routine method so 582 00:25:13,550 --> 00:25:17,510 that the population is well informed on 583 00:25:17,510 --> 00:25:19,732 that they know where to get the vaccine 584 00:25:19,732 --> 00:25:22,140 and when to get the vaccine on DSO 585 00:25:22,140 --> 00:25:24,830 Those two points were driving home as 586 00:25:24,830 --> 00:25:28,140 key essential tasks at our level . And 587 00:25:28,140 --> 00:25:30,800 so , Mr Secretary , thank you , Paws . 588 00:25:30,810 --> 00:25:33,420 So , Aziz , we get ready for questions . 589 00:25:33,420 --> 00:25:35,700 I just wanna include the opening by 590 00:25:35,710 --> 00:25:38,420 expressing my deep appreciation Thio 591 00:25:38,430 --> 00:25:40,541 Doctor Slowly and General Purna . You 592 00:25:40,541 --> 00:25:42,541 know , whenever I created Operation 593 00:25:42,541 --> 00:25:45,560 Warp Speed , I I called around to 594 00:25:45,570 --> 00:25:47,626 people in the industry , experts and 595 00:25:47,626 --> 00:25:50,700 vaccines and everybody said , The 596 00:25:50,700 --> 00:25:52,756 person that you need leading this is 597 00:25:52,756 --> 00:25:55,820 Moncef slowly , um , the world's 598 00:25:55,830 --> 00:25:58,350 leading vaccine developer with the 599 00:25:58,350 --> 00:26:00,350 greatest track record of delivering 600 00:26:00,350 --> 00:26:03,980 results on . He has proven that I met 601 00:26:03,980 --> 00:26:06,091 with the secretary of Defense and the 602 00:26:06,091 --> 00:26:08,313 chairman of the Joint Chiefs , and they 603 00:26:08,313 --> 00:26:10,480 immediately said , The person you need 604 00:26:10,480 --> 00:26:12,424 leading this effort is General Gus 605 00:26:12,424 --> 00:26:14,660 purdah and it is the American people 606 00:26:14,660 --> 00:26:17,170 are a deep , deep debt of gratitude to 607 00:26:17,170 --> 00:26:19,230 these two individuals as well as the 608 00:26:19,240 --> 00:26:22,710 hundreds of people on their teams who 609 00:26:22,710 --> 00:26:24,710 are who are delivering the kinds of 610 00:26:24,710 --> 00:26:26,821 results historic results that we have 611 00:26:26,821 --> 00:26:29,170 seen in the last week . So we'll turn 612 00:26:29,170 --> 00:26:31,503 now to questions . Thank you , Operator . 613 00:26:31,503 --> 00:26:33,614 We can now open it up for questions . 614 00:26:35,140 --> 00:26:37,362 Thank you . At this time , if you would 615 00:26:37,362 --> 00:26:39,529 like to ask a question , you may press 616 00:26:39,529 --> 00:26:41,770 star one , please meet your phones on 617 00:26:41,770 --> 00:26:43,492 state your first and last name 618 00:26:43,492 --> 00:26:45,659 unprompted to withdraw your question . 619 00:26:45,659 --> 00:26:47,940 You may press star to one moment , 620 00:26:47,940 --> 00:26:50,440 please . For the first question back , 621 00:26:50,440 --> 00:26:52,773 Ray Brennan , you may go ahead and play . 622 00:26:52,773 --> 00:26:55,550 State your outlet . Hi . Thanks for 623 00:26:55,550 --> 00:26:57,883 taking the question . I'm with Politico . 624 00:26:57,883 --> 00:26:59,828 So I'm curious if someone can talk 625 00:26:59,828 --> 00:27:02,160 about federal plans for vaccine waste . 626 00:27:02,170 --> 00:27:04,170 So say you're trying to vaccinate a 627 00:27:04,170 --> 00:27:07,710 hospital with 37 doctors on the Pfizer 628 00:27:07,710 --> 00:27:09,766 vaccine . Only comes in , you know , 629 00:27:09,766 --> 00:27:12,620 five doses per vial in 195 miles per 630 00:27:12,620 --> 00:27:15,590 container . What ? What is the plan for 631 00:27:15,590 --> 00:27:17,590 those remaining doses that might be 632 00:27:17,590 --> 00:27:20,060 left over ? Let me ask General Partner . 633 00:27:20,070 --> 00:27:22,960 Thank you , Secretary . So really 634 00:27:22,960 --> 00:27:24,960 important question . And we've been 635 00:27:24,960 --> 00:27:27,127 working hard with the jurisdictions to 636 00:27:27,127 --> 00:27:30,060 make sure that the plan , um , provides 637 00:27:30,060 --> 00:27:33,140 the details to that end . So you you 638 00:27:33,150 --> 00:27:35,500 mentioned it . Visor comes at a minimum 639 00:27:35,500 --> 00:27:39,100 package of 975 doses portray , and 640 00:27:39,100 --> 00:27:42,170 Madonna comes in at 100 doses . Portray 641 00:27:42,640 --> 00:27:44,862 with that said , though that's on Lee a 642 00:27:44,862 --> 00:27:47,270 constraint because of what we have to 643 00:27:47,270 --> 00:27:48,992 do to maintain it at the right 644 00:27:48,992 --> 00:27:51,240 temperature for stability so you can 645 00:27:51,240 --> 00:27:54,320 break down both vaccines , right ? You 646 00:27:54,320 --> 00:27:57,430 can pull out quantities of what you 647 00:27:57,430 --> 00:28:00,930 want to execute and put them , reduce 648 00:28:00,930 --> 00:28:03,420 them and put them into the eight normal 649 00:28:03,420 --> 00:28:06,520 refrigeration on , then execute them 650 00:28:06,520 --> 00:28:09,590 within five days . That's the key . So 651 00:28:09,590 --> 00:28:13,470 it's the it's the planning , the 652 00:28:13,840 --> 00:28:17,230 specified execution that we're counting 653 00:28:17,240 --> 00:28:19,351 on and the states have been working . 654 00:28:19,351 --> 00:28:21,462 This one of the reasons that we asked 655 00:28:21,462 --> 00:28:24,270 and we brought Walgreens and CVS in 656 00:28:24,270 --> 00:28:26,550 special is the secretary mentioned is 657 00:28:26,550 --> 00:28:28,550 because they know how to break this 658 00:28:28,550 --> 00:28:31,170 down and do small quantities for 659 00:28:31,170 --> 00:28:34,250 important groups . And so way worked 660 00:28:34,260 --> 00:28:37,090 very detailed plans with them on . 661 00:28:37,090 --> 00:28:38,979 We're collaborating that with the 662 00:28:38,979 --> 00:28:41,660 jurisdictions to make sure that no 663 00:28:41,660 --> 00:28:44,730 vaccine is wasted on that when they go 664 00:28:44,730 --> 00:28:47,760 Thio immunize its specified places , 665 00:28:47,770 --> 00:28:51,410 they have the right techniques on 666 00:28:51,410 --> 00:28:54,050 besiegers to make sure that Onley the 667 00:28:54,050 --> 00:28:57,240 required doses are reduced to the right 668 00:28:57,240 --> 00:28:59,480 temperature for administration and that 669 00:28:59,480 --> 00:29:02,550 the others stay in the appropriate , uh , 670 00:29:02,560 --> 00:29:05,090 temperature for stability . Thank you . 671 00:29:05,100 --> 00:29:08,950 Next question . Thank 672 00:29:08,950 --> 00:29:10,950 you . Next question comes from Evan 673 00:29:10,950 --> 00:29:12,950 Brown . You may go ahead and please 674 00:29:12,950 --> 00:29:15,560 state your outlet . Hi . Good afternoon . 675 00:29:15,560 --> 00:29:18,510 Evan Brown from Fox News . Um , Thio 676 00:29:18,520 --> 00:29:20,631 Piggyback on the last question . Um , 677 00:29:20,631 --> 00:29:22,798 there has been a lot of talk about the 678 00:29:22,798 --> 00:29:24,950 need for refrigerating the Pfizer 679 00:29:24,950 --> 00:29:27,740 vaccine at extremely low temperature . 680 00:29:27,750 --> 00:29:30,450 Are there plans , uh , to either 681 00:29:30,450 --> 00:29:32,970 provide mawr of these refrigeration 682 00:29:32,970 --> 00:29:35,390 units to either retail pharmacies or 683 00:29:35,390 --> 00:29:37,612 health care facilities ? Eyes , they're 684 00:29:37,612 --> 00:29:39,950 away . Um , and I'm thinking back 685 00:29:39,960 --> 00:29:42,140 earlier this year , the the ability 686 00:29:42,140 --> 00:29:44,307 Thio ramp up production on things like 687 00:29:44,307 --> 00:29:46,529 ventilators . Is there a way to ramp up 688 00:29:46,529 --> 00:29:48,640 production either through the defense 689 00:29:48,640 --> 00:29:50,973 production actors ? Something else , um , 690 00:29:50,973 --> 00:29:53,029 to build more of these refrigeration 691 00:29:53,029 --> 00:29:55,084 units to get them where they need to 692 00:29:55,084 --> 00:29:56,973 bay . I'll ask general partner to 693 00:29:56,973 --> 00:29:59,029 continue on that discussion . Do you 694 00:29:59,029 --> 00:30:01,084 mind other yourself for Dr Slow ? We 695 00:30:01,084 --> 00:30:03,307 also want to get out there . The latest 696 00:30:03,307 --> 00:30:05,473 information that we have that's public 697 00:30:05,473 --> 00:30:07,529 around temperature stability on both 698 00:30:07,529 --> 00:30:09,529 the Madonna vaccine and the fighter 699 00:30:09,529 --> 00:30:11,418 vaccine . I think that will be an 700 00:30:11,418 --> 00:30:13,529 important technical clarification for 701 00:30:13,529 --> 00:30:15,640 people . But perhaps first general on 702 00:30:15,640 --> 00:30:17,862 the just the cold storage on Pfizer and 703 00:30:17,862 --> 00:30:20,084 equipment first , I'm just , you know , 704 00:30:20,084 --> 00:30:21,973 Dr Salah we laid it out for us is 705 00:30:21,973 --> 00:30:24,520 usually incredibly well , um , I will 706 00:30:24,520 --> 00:30:26,860 tell you that both the Pfizer vaccine 707 00:30:26,860 --> 00:30:29,170 and Madonna vaccine , as he said , are 708 00:30:29,180 --> 00:30:30,958 you know , these air just these 709 00:30:30,958 --> 00:30:33,069 vaccines are ready to be administered 710 00:30:33,069 --> 00:30:35,200 on what I've been coaching 711 00:30:35,210 --> 00:30:38,970 jurisdictions Eyes don't be afraid of 712 00:30:38,970 --> 00:30:41,810 the constraints because of the vaccine 713 00:30:41,810 --> 00:30:44,160 and the temperature requirements . We 714 00:30:44,160 --> 00:30:46,690 have walked through every individual 715 00:30:46,690 --> 00:30:50,330 step on how to maintain Pfizer 716 00:30:50,330 --> 00:30:54,110 vaccine with ultra cold refrigeration 717 00:30:54,240 --> 00:30:56,470 as well as what does it need if it's 718 00:30:56,480 --> 00:30:58,450 maintained in the box that it's 719 00:30:58,450 --> 00:31:02,310 delivered via dry ice with excruciating 720 00:31:02,310 --> 00:31:06,020 detail . So first we know where all the 721 00:31:06,020 --> 00:31:09,090 ultra cold storage refrigeration is in 722 00:31:09,090 --> 00:31:10,880 the country that we asked the 723 00:31:10,880 --> 00:31:13,370 jurisdictions months ago for this data , 724 00:31:13,380 --> 00:31:15,602 they went and identified it and tracked 725 00:31:15,602 --> 00:31:19,110 it down . They also were provided the 726 00:31:19,120 --> 00:31:22,170 with resource is on how to go by mawr 727 00:31:22,170 --> 00:31:24,830 refrigeration . If they wanted to , uh , 728 00:31:24,840 --> 00:31:27,490 to increase the distribution capability 729 00:31:27,490 --> 00:31:29,980 throughout their jurisdiction . Uh , if 730 00:31:29,980 --> 00:31:31,980 it was required , many states don't 731 00:31:31,980 --> 00:31:34,870 require additional uh , refrigeration . 732 00:31:34,870 --> 00:31:37,360 They have enough and or how do they 733 00:31:37,360 --> 00:31:40,760 supplement with dry ice as accordingly ? 734 00:31:40,840 --> 00:31:42,990 So we we've laid all that out . My 735 00:31:42,990 --> 00:31:45,590 message . Don't be afraid of the 736 00:31:45,590 --> 00:31:47,730 refrigeration requirement . The 737 00:31:47,730 --> 00:31:51,090 capability exists if more is needed , 738 00:31:51,250 --> 00:31:54,410 the capability exists to purchase and 739 00:31:54,410 --> 00:31:56,466 have it delivered in a timely manner 740 00:31:56,466 --> 00:32:00,040 for both refrigeration and dry ice on 741 00:32:00,040 --> 00:32:03,190 then , I think , Yeah , so I think I 742 00:32:03,190 --> 00:32:05,860 think keeping the vaccines refrigerated 743 00:32:06,240 --> 00:32:10,020 when there are stores in Mass is not an 744 00:32:10,020 --> 00:32:12,020 issue . As General just explained , 745 00:32:12,340 --> 00:32:14,530 it's important to know once you throw 746 00:32:14,530 --> 00:32:17,670 them for the modern a vaccine , you can 747 00:32:17,680 --> 00:32:21,160 keep that vile food for a month . 748 00:32:21,840 --> 00:32:25,210 30 days at 2 to 8 degrees . That's 749 00:32:25,210 --> 00:32:27,432 enough time . Each vial has 10 those of 750 00:32:27,432 --> 00:32:29,710 vaccine . That's enough time clearly to 751 00:32:29,710 --> 00:32:32,660 immunize 10 individuals in the case of 752 00:32:33,040 --> 00:32:35,262 the fighter vaccine you can throw . The 753 00:32:35,262 --> 00:32:37,207 vial also contains 10 . Those is a 754 00:32:37,207 --> 00:32:39,429 vaccine . You can keep it for five days 755 00:32:39,680 --> 00:32:42,470 at 2 to 8 degrees . That's ample time 756 00:32:42,750 --> 00:32:45,028 to immunize in the setting of epidemic . 757 00:32:45,120 --> 00:32:47,720 So clearly we feel very comfortable 758 00:32:47,720 --> 00:32:51,230 that there would be minimum wasted on . 759 00:32:51,240 --> 00:32:54,970 I can tell you everything is planned to 760 00:32:54,970 --> 00:32:57,600 the minute I'm learning about how the 761 00:32:57,600 --> 00:33:01,340 Army wins wars a little bit . It's 762 00:33:01,340 --> 00:33:03,780 impressive . Great . Thank you . Next 763 00:33:03,780 --> 00:33:07,180 question . Thank you . Beth Long . You 764 00:33:07,180 --> 00:33:09,124 may go ahead and please state your 765 00:33:09,124 --> 00:33:12,920 outlet . Hi . Thank you . 766 00:33:12,920 --> 00:33:14,920 And best , along with inside health 767 00:33:14,920 --> 00:33:17,031 policy , I'm wondering , with both of 768 00:33:17,031 --> 00:33:19,030 these vaccines potentially getting 769 00:33:19,030 --> 00:33:21,570 anyway , um , clearance around the same 770 00:33:21,570 --> 00:33:23,840 time , How will you determine for how 771 00:33:23,840 --> 00:33:26,430 will it be determined ? Who gets which 772 00:33:26,430 --> 00:33:28,930 vaccine if they're both available ? And , 773 00:33:28,940 --> 00:33:32,130 um also , how much of the population do 774 00:33:32,130 --> 00:33:34,297 you expect will need to get vaccinated 775 00:33:34,297 --> 00:33:36,930 to achieve widespread immunity ? Well , 776 00:33:36,930 --> 00:33:39,041 it's Dr Slowly if he could start with 777 00:33:39,041 --> 00:33:41,270 that . I think we are in the fortunate 778 00:33:41,270 --> 00:33:43,270 position at this stage that the two 779 00:33:43,270 --> 00:33:44,992 vaccines have almost identical 780 00:33:44,992 --> 00:33:48,760 performance on off course . It will 781 00:33:48,770 --> 00:33:52,690 all depend on the reviews by the FDA on 782 00:33:52,700 --> 00:33:56,370 the minutia of the data . Exactly what 783 00:33:56,370 --> 00:33:58,680 label and the safety profile etcetera . 784 00:33:58,680 --> 00:34:01,750 But they they are very similar in there , 785 00:34:01,750 --> 00:34:04,660 making and in their performance . And 786 00:34:04,660 --> 00:34:06,827 therefore , I don't think there should 787 00:34:06,827 --> 00:34:09,230 be any constraints on who gets what 788 00:34:09,230 --> 00:34:11,840 vaccine . I think one in the hand is 789 00:34:11,840 --> 00:34:14,007 better than two in the bush . Here you 790 00:34:14,007 --> 00:34:16,229 take the vaccine that's available would 791 00:34:16,229 --> 00:34:18,229 be my personal recommendation , but 792 00:34:18,229 --> 00:34:20,880 obviously the 100 ACP will . We'll make 793 00:34:20,880 --> 00:34:23,180 that call . In regard of your second 794 00:34:23,180 --> 00:34:26,370 point . This level of efficacy very 795 00:34:26,370 --> 00:34:28,640 impressive , frankly , needs to be 796 00:34:28,640 --> 00:34:31,070 complemented its efficacy against 797 00:34:31,080 --> 00:34:34,110 disease . We need to and we will be 798 00:34:34,110 --> 00:34:36,340 able to assess the capacity of these 799 00:34:36,340 --> 00:34:38,910 vaccines to have also prevented 800 00:34:38,910 --> 00:34:42,270 infection Or , if there is infection , 801 00:34:42,270 --> 00:34:45,460 whether they impact amount of virus 802 00:34:45,460 --> 00:34:48,170 load that we have that sheds through 803 00:34:48,170 --> 00:34:51,750 which we , in fact , other people most 804 00:34:51,750 --> 00:34:53,940 likely they are effective against 805 00:34:53,940 --> 00:34:57,200 infection . Maybe not at 95% . And most 806 00:34:57,200 --> 00:34:59,422 likely they are effective at decreasing 807 00:34:59,422 --> 00:35:01,756 virus load and therefore virus shedding . 808 00:35:01,930 --> 00:35:04,097 Therefore , they should have an impact 809 00:35:04,097 --> 00:35:07,020 on transmission . People model that 810 00:35:07,030 --> 00:35:09,680 anything north off 70% of the 811 00:35:09,680 --> 00:35:12,150 population being immunized should 812 00:35:12,160 --> 00:35:15,070 decrease substantially the pressure off 813 00:35:15,080 --> 00:35:17,800 virus circulating and therefore 814 00:35:17,900 --> 00:35:20,690 substantially achieve herd immunity . 815 00:35:21,440 --> 00:35:25,130 Great , please . So just add to that 816 00:35:25,130 --> 00:35:28,490 we're ready to distribute both vaccines 817 00:35:28,500 --> 00:35:31,200 upon you a approval in the fair and 818 00:35:31,200 --> 00:35:33,910 equitable , uh , distribution manner 819 00:35:33,910 --> 00:35:36,650 that I discussed earlier . We are ready 820 00:35:36,650 --> 00:35:40,200 toe simultaneously . If you a occurs to 821 00:35:40,200 --> 00:35:43,250 ship both toe all 64 jurisdictions . 822 00:35:44,240 --> 00:35:47,530 Thank you . Next question . Thank you . 823 00:35:47,530 --> 00:35:49,863 Carol . Donald , please get your outlet . 824 00:35:52,240 --> 00:35:54,351 Hi . This is Carl O Donnell . Reuters 825 00:35:54,351 --> 00:35:57,080 news . Um , just just two questions 826 00:35:57,080 --> 00:35:59,024 kind of building on on what's been 827 00:35:59,024 --> 00:36:01,360 asked . Do you do you forsee , um , 828 00:36:01,370 --> 00:36:05,040 Madonna's vaccine being mawr prevalent 829 00:36:05,050 --> 00:36:07,360 on DSHEA shipped in in proportionately 830 00:36:07,360 --> 00:36:10,380 larger quantities to rural areas and 831 00:36:10,380 --> 00:36:12,436 other hard to reach areas . Given it 832 00:36:12,930 --> 00:36:16,640 significantly , um , you know , less 833 00:36:16,650 --> 00:36:18,840 constraining storage requirements on 834 00:36:18,860 --> 00:36:20,971 Also , do you forsee there being some 835 00:36:20,971 --> 00:36:23,240 period of time where Onley the Pfizer 836 00:36:23,240 --> 00:36:25,830 vaccine is available ? Just given the 837 00:36:25,830 --> 00:36:28,052 timing of the EU ways , that's likely . 838 00:36:28,052 --> 00:36:30,219 Thank you . Good question . Let me ask 839 00:36:30,219 --> 00:36:32,640 General partner . So Aziz , Dr Salah we 840 00:36:32,640 --> 00:36:34,862 talked about earlier . You know , we're 841 00:36:34,862 --> 00:36:37,029 gonna wait for the science to lay some 842 00:36:37,029 --> 00:36:39,510 things out for us on then we're going 843 00:36:39,510 --> 00:36:41,580 to execute the plans that the 844 00:36:41,580 --> 00:36:44,180 jurisdictions have established . Um , 845 00:36:44,190 --> 00:36:46,740 once they figure out the priority and 846 00:36:46,750 --> 00:36:48,806 you know where they wanted to go , I 847 00:36:48,806 --> 00:36:50,583 will tell you that we've worked 848 00:36:50,583 --> 00:36:53,650 excruciating details to ensure that 849 00:36:53,660 --> 00:36:57,110 every area is being thought about 850 00:36:57,110 --> 00:36:59,620 whether it's inner city or extreme 851 00:36:59,620 --> 00:37:03,320 rural , uh , areas , so that we have 852 00:37:03,320 --> 00:37:05,700 the capability and capacity to do so . 853 00:37:05,710 --> 00:37:08,420 Really ? Again . The connection is our 854 00:37:08,420 --> 00:37:11,620 ability to partner with industry , you 855 00:37:11,620 --> 00:37:14,620 know , both distribution and pharma for 856 00:37:14,620 --> 00:37:16,731 administration to really achieve that 857 00:37:16,731 --> 00:37:18,676 success and that , and that's Ah , 858 00:37:18,676 --> 00:37:21,200 Karla . That's partly why , when the 859 00:37:21,200 --> 00:37:23,520 CDC and General Pernas distribution 860 00:37:23,520 --> 00:37:26,390 team worked with 64 jurisdictions , we 861 00:37:26,390 --> 00:37:28,334 actually gave them to hypothetical 862 00:37:28,334 --> 00:37:31,270 vaccines with these types of profiles 863 00:37:31,270 --> 00:37:33,710 described on the Madonna and the Pfizer 864 00:37:33,710 --> 00:37:36,020 vaccine profiles . So that as they 865 00:37:36,020 --> 00:37:38,520 think about which outlets they would 866 00:37:38,520 --> 00:37:41,160 want to use and designate for US tow 867 00:37:41,170 --> 00:37:44,080 ship to or have shipped to , that that 868 00:37:44,080 --> 00:37:46,080 they would fit those kinds of those 869 00:37:46,080 --> 00:37:48,191 profiles . So I think it's been built 870 00:37:48,191 --> 00:37:50,640 into their jurisdictional planning . In 871 00:37:50,640 --> 00:37:52,590 regard of your question on the lag 872 00:37:52,590 --> 00:37:54,312 between the two vaccines being 873 00:37:54,312 --> 00:37:56,590 available , A Z You know , we're 874 00:37:56,590 --> 00:37:58,730 probably talking about a week or 10 875 00:37:58,730 --> 00:38:01,940 days . It will be a call of the FDA as 876 00:38:01,940 --> 00:38:03,996 they review the files , whether they 877 00:38:03,996 --> 00:38:06,560 will hold one pack or two different 878 00:38:06,560 --> 00:38:09,590 verb packs . But the lag time between 879 00:38:09,590 --> 00:38:11,701 the two vaccine is going to be very , 880 00:38:11,701 --> 00:38:13,646 very , very minimal . Great . Next 881 00:38:13,646 --> 00:38:16,310 question . Stephanie ups . You may go 882 00:38:16,310 --> 00:38:19,420 ahead . Please get your outlet . Thank 883 00:38:19,420 --> 00:38:21,930 you . This Stephanie ebbs from ABC News . 884 00:38:21,940 --> 00:38:25,130 Can you walk us through a bit ? A bit 885 00:38:25,130 --> 00:38:27,430 more detail ? What might happen in that 886 00:38:27,440 --> 00:38:30,350 24 hours between you and shipments . 887 00:38:30,720 --> 00:38:32,776 And specifically , do you anticipate 888 00:38:32,776 --> 00:38:35,580 that the A sip committee would meet and 889 00:38:35,580 --> 00:38:38,080 determine recommendations for how to 890 00:38:38,080 --> 00:38:40,310 prioritize that initial shipment of 891 00:38:40,320 --> 00:38:42,660 doses before it goes out to states or 892 00:38:42,660 --> 00:38:45,000 after ? Yes , so Stephanie ? That's an 893 00:38:45,000 --> 00:38:47,390 excellent question on I'm working 894 00:38:47,400 --> 00:38:50,830 directly with the CDC director Robert 895 00:38:50,830 --> 00:38:54,130 Redfield on how we could convene the A 896 00:38:54,130 --> 00:38:56,390 C I . P . Hopefully concurrent with the 897 00:38:56,390 --> 00:38:59,260 FDA review . Customarily , they wait 898 00:38:59,260 --> 00:39:02,170 until there's a license from the FDA , 899 00:39:02,180 --> 00:39:05,450 and then 48 hours later we'll meet and 900 00:39:05,450 --> 00:39:07,790 provide advice out . But we're working 901 00:39:07,790 --> 00:39:09,957 to see if we can actually facilitate a 902 00:39:09,957 --> 00:39:11,960 concurrent review process that's 903 00:39:11,960 --> 00:39:14,127 collaborative with the FDA sharing the 904 00:39:14,127 --> 00:39:16,450 whatever information the pipe would 905 00:39:16,450 --> 00:39:18,561 need to do its job so that it doesn't 906 00:39:18,561 --> 00:39:20,990 add any extra delay with over 1000 907 00:39:20,990 --> 00:39:24,700 people perishing per day . We want Thio . 908 00:39:24,710 --> 00:39:26,877 Our mission at Operation Warp speed is 909 00:39:26,877 --> 00:39:29,300 about saving lives every hour , every 910 00:39:29,300 --> 00:39:31,411 day matters . And so we're gonna work 911 00:39:31,411 --> 00:39:33,411 to try to minimize that any type of 912 00:39:33,411 --> 00:39:35,450 delay there . Next question , 913 00:39:37,320 --> 00:39:39,264 Tom , how he may go ahead . Please 914 00:39:39,264 --> 00:39:41,910 state your outlet . Hi , this is Tom 915 00:39:41,910 --> 00:39:43,966 Howell from the Washington Times . I 916 00:39:43,966 --> 00:39:46,132 just want to know if you could give us 917 00:39:46,132 --> 00:39:48,354 a sense of what type of storage will be 918 00:39:48,354 --> 00:39:50,466 used in different settings . In other 919 00:39:50,466 --> 00:39:52,743 words , there's the ultra low freezers . 920 00:39:52,743 --> 00:39:54,966 There's the refrigeration for a certain 921 00:39:54,966 --> 00:39:54,800 amount of day . There's a dry ice and 922 00:39:54,800 --> 00:39:57,000 thermal shippers . Um , which kind of 923 00:39:57,000 --> 00:39:59,222 places will be using which , you know , 924 00:39:59,222 --> 00:40:01,444 hospitals , large , aging , large chain 925 00:40:01,444 --> 00:40:03,500 pharmacies ? Have you sort of that ? 926 00:40:03,500 --> 00:40:05,820 Elliott Mhm . So mostly hospitals . 927 00:40:05,820 --> 00:40:09,170 Universities on the farmer chains have 928 00:40:09,170 --> 00:40:12,240 the ultra cold storage capacity . It 929 00:40:12,240 --> 00:40:14,580 ranges from different volumes of 930 00:40:14,580 --> 00:40:17,990 capacity , uh , maintaining hundreds of 931 00:40:17,990 --> 00:40:21,300 thousands of doses to just limited 932 00:40:21,310 --> 00:40:24,300 maybe one or two trays , a ZAY said 933 00:40:24,300 --> 00:40:26,244 earlier . We have those pinpointed 934 00:40:26,244 --> 00:40:28,078 throughout the country . We know 935 00:40:28,078 --> 00:40:30,189 exactly where they are on how they're 936 00:40:30,189 --> 00:40:32,750 fitting into the jurisdiction plans for 937 00:40:32,750 --> 00:40:36,300 distribution . What we've done to 938 00:40:36,300 --> 00:40:39,520 really help mitigate the 939 00:40:39,530 --> 00:40:42,900 distribution off that vaccine outside 940 00:40:42,900 --> 00:40:45,520 of ultra cold storage availability is 941 00:40:45,520 --> 00:40:48,260 partner with pharma , in particular CVS 942 00:40:48,260 --> 00:40:50,620 and Walgreens , who have mobile 943 00:40:50,620 --> 00:40:54,050 capability for both ultra cold Azaz . 944 00:40:54,050 --> 00:40:57,390 Well as how to distribute out of the 945 00:40:57,390 --> 00:41:00,830 farmer out of Excuse me , Pfizer uh , 946 00:41:00,840 --> 00:41:03,090 distribution boxes , which contain 947 00:41:03,100 --> 00:41:06,570 contain dry ice there well instructed 948 00:41:06,580 --> 00:41:09,760 on how to manage the dry ice to ensure 949 00:41:09,760 --> 00:41:11,700 that the stability of the vaccine 950 00:41:11,710 --> 00:41:13,770 remains the same throughout 951 00:41:13,780 --> 00:41:17,460 distribution . The second point to that 952 00:41:17,460 --> 00:41:21,460 end is that we're partnering with the 953 00:41:21,460 --> 00:41:25,260 states , the jurisdictions on Pharma to 954 00:41:25,260 --> 00:41:29,200 ensure the plan based on how maney 955 00:41:29,200 --> 00:41:32,560 doses that we distribute initially and 956 00:41:32,560 --> 00:41:35,610 then through the cadence , right can be , 957 00:41:35,620 --> 00:41:38,030 um , What's the word I want to use ? We 958 00:41:38,030 --> 00:41:40,710 want to lead her away through execution 959 00:41:40,720 --> 00:41:43,640 so that distribution will be through 960 00:41:43,650 --> 00:41:47,180 organization organizations that allow 961 00:41:47,190 --> 00:41:51,090 people to be notified on Be ready for 962 00:41:51,100 --> 00:41:53,322 the administration of a shot , at least 963 00:41:53,322 --> 00:41:55,950 initially through maybe December 964 00:41:55,950 --> 00:41:58,550 January time frame until we have more 965 00:41:58,550 --> 00:42:00,770 vaccines that will be available 966 00:42:00,770 --> 00:42:03,310 throughout at many different locations . 967 00:42:04,000 --> 00:42:07,840 Next question , Peter Loftus . You may 968 00:42:07,840 --> 00:42:09,951 go ahead . Please state your outlet . 969 00:42:11,400 --> 00:42:13,511 I feel locked us from the Wall Street 970 00:42:13,511 --> 00:42:15,720 Journal . What steps are you taking to 971 00:42:15,720 --> 00:42:17,830 ensure that this whole process 972 00:42:17,840 --> 00:42:20,150 continues to go smoothly in the 973 00:42:20,150 --> 00:42:22,740 transition to the next administration ? 974 00:42:23,400 --> 00:42:25,770 Yeah , so ? So , Peter , in the event 975 00:42:25,770 --> 00:42:27,937 of a transition , the individuals that 976 00:42:27,937 --> 00:42:30,103 you're seeing here other than myself , 977 00:42:30,103 --> 00:42:32,048 all of the individuals involved in 978 00:42:32,048 --> 00:42:34,103 planning at CDC and on the Operation 979 00:42:34,103 --> 00:42:36,214 Warp speed team Uh , these air career 980 00:42:36,214 --> 00:42:38,326 officials eso they aren't impacted by 981 00:42:38,326 --> 00:42:40,610 any change in leadership . Uh , this . 982 00:42:40,610 --> 00:42:43,300 The work with the states is is deeply 983 00:42:43,300 --> 00:42:45,560 embedded with hundreds work processes . 984 00:42:45,560 --> 00:42:47,640 So in the event of a transition , 985 00:42:47,640 --> 00:42:49,529 there's there's really just total 986 00:42:49,529 --> 00:42:51,196 continuity that would occur . 987 00:42:54,900 --> 00:42:58,280 Next question , Emily Cox , you may go 988 00:42:58,280 --> 00:43:00,224 ahead , please state your outlet . 989 00:43:02,100 --> 00:43:04,267 Hi , this is Emily caught with CQ roll 990 00:43:04,267 --> 00:43:06,100 call . Um , Secretary is there . 991 00:43:06,100 --> 00:43:09,740 There's a CNN report that BHS staffers 992 00:43:09,740 --> 00:43:11,907 have been instructed that if they hear 993 00:43:11,907 --> 00:43:13,962 from anyone with President elect Joe 994 00:43:13,962 --> 00:43:16,080 Biden's team that they are not to 995 00:43:16,080 --> 00:43:18,247 communicate with them . So I wanted to 996 00:43:18,247 --> 00:43:20,469 get your response to that . Um and then 997 00:43:20,469 --> 00:43:22,524 I also wanted to ask , um you know , 998 00:43:22,524 --> 00:43:24,636 I've heard a lot today about the role 999 00:43:24,636 --> 00:43:26,691 of the 64 individual jurisdictions . 1000 00:43:26,691 --> 00:43:29,050 Are you encouraging ? Um , the vice 1001 00:43:29,050 --> 00:43:31,430 president or the president elected Thio 1002 00:43:31,440 --> 00:43:33,107 reach out to those individual 1003 00:43:33,110 --> 00:43:35,054 jurisdictions , toe , find out the 1004 00:43:35,054 --> 00:43:38,600 plans in lieu of more meaningful 1005 00:43:38,610 --> 00:43:40,960 collaboration at the federal level . So 1006 00:43:40,960 --> 00:43:43,700 we we've made it very clear that when G 1007 00:43:43,700 --> 00:43:46,720 s A makes a determination , we will 1008 00:43:46,720 --> 00:43:49,020 ensure complete cooperative 1009 00:43:49,020 --> 00:43:52,030 professional transitions on planning . 1010 00:43:52,040 --> 00:43:54,750 But that's ah way follow the guidance 1011 00:43:54,750 --> 00:43:56,528 were about getting vaccines and 1012 00:43:56,528 --> 00:43:59,020 therapeutics invented and get the 1013 00:43:59,020 --> 00:44:01,076 clinical trial data and saving lives 1014 00:44:01,076 --> 00:44:03,020 here That's where that's where our 1015 00:44:03,020 --> 00:44:05,300 focus is . Aziz , We go forward with 1016 00:44:05,300 --> 00:44:07,780 our efforts . Operator , we have time 1017 00:44:07,780 --> 00:44:10,710 for two more questions . Thank you , 1018 00:44:10,720 --> 00:44:12,776 Charles Fishman . You may go ahead . 1019 00:44:12,776 --> 00:44:15,640 Please . Get your outlet , Uh , Charles 1020 00:44:15,640 --> 00:44:18,530 Fishman with the Atlantic . A two part 1021 00:44:18,530 --> 00:44:21,530 question about dry ice . Can you tell 1022 00:44:21,530 --> 00:44:24,490 us roughly how many of the places 1023 00:44:24,490 --> 00:44:27,320 receiving the vaccine have the ultra 1024 00:44:27,320 --> 00:44:30,710 cold freezers and how many rely on dry 1025 00:44:30,710 --> 00:44:33,510 ice Just as a percentage . And I think 1026 00:44:33,510 --> 00:44:36,010 last week or the previous week 1027 00:44:36,020 --> 00:44:39,270 operation works . He said it would 1028 00:44:39,270 --> 00:44:42,520 provide to the places that need by ice 1029 00:44:42,530 --> 00:44:46,050 the first recharge the 1st 7 1030 00:44:46,060 --> 00:44:49,350 £50 for each container . Can you tell 1031 00:44:49,350 --> 00:44:51,840 us how you're going to do that ? Where 1032 00:44:51,840 --> 00:44:54,040 is that dry ice going to come from and 1033 00:44:54,040 --> 00:44:55,929 how they're going to get to those 1034 00:44:55,929 --> 00:44:58,096 people who need it the day the vaccine 1035 00:44:58,096 --> 00:45:01,480 arrives ? Okay , So initially , I don't 1036 00:45:01,480 --> 00:45:04,280 see any place where the vaccine is 1037 00:45:04,280 --> 00:45:06,224 delivered that it won't go into an 1038 00:45:06,224 --> 00:45:09,180 ultra cold storage refrigerator . You 1039 00:45:09,180 --> 00:45:11,069 know , as we are dealing with the 1040 00:45:11,069 --> 00:45:13,270 initial doses available on , we're 1041 00:45:13,270 --> 00:45:15,470 distributing accordingly . We've 1042 00:45:15,480 --> 00:45:17,258 coordinated and we've asked the 1043 00:45:17,258 --> 00:45:19,700 jurisdictions the plan for it to go 1044 00:45:19,710 --> 00:45:22,580 right into that type of capability so 1045 00:45:22,580 --> 00:45:24,630 that we can learn and transition 1046 00:45:24,630 --> 00:45:27,760 together . Aziz , we expand doses 1047 00:45:27,760 --> 00:45:29,870 available thio each of the 1048 00:45:29,870 --> 00:45:32,410 jurisdictions . So initially , I 1049 00:45:32,410 --> 00:45:34,630 believe all will go into ultra cold 1050 00:45:34,630 --> 00:45:38,300 storage refrigeration . Second point to 1051 00:45:38,300 --> 00:45:41,370 your question about the dry ice we did 1052 00:45:41,380 --> 00:45:44,290 on we have coordinated on contract ID 1053 00:45:44,290 --> 00:45:48,280 for the first , um , refresh of dry 1054 00:45:48,280 --> 00:45:51,370 ice to all that we distribute if it is 1055 00:45:51,370 --> 00:45:54,790 required . If it goes into the ultra 1056 00:45:54,790 --> 00:45:56,846 cold storage like I just said , then 1057 00:45:56,846 --> 00:45:59,270 it's not required . But there is surely 1058 00:45:59,270 --> 00:46:01,840 to be exceptions . Azzawi work through 1059 00:46:01,850 --> 00:46:04,990 every detail across 64 jurisdictions 1060 00:46:05,280 --> 00:46:07,620 from the Pacific , all the way through 1061 00:46:07,620 --> 00:46:11,170 the Northeast on then down to the south 1062 00:46:11,290 --> 00:46:13,960 east and then back up to the northwest . 1063 00:46:13,970 --> 00:46:16,540 There is going in exception on . I 1064 00:46:16,540 --> 00:46:18,651 wanted to make sure we were ready for 1065 00:46:18,651 --> 00:46:21,260 that . So we've coordinated industry , 1066 00:46:21,270 --> 00:46:24,150 um , commercial industry for dry ice 1067 00:46:24,150 --> 00:46:26,500 production . We've we've coordinated 1068 00:46:26,510 --> 00:46:29,000 through them as well as in particular 1069 00:46:29,000 --> 00:46:31,990 Pfizer toe help with this on then , 1070 00:46:31,990 --> 00:46:35,060 distribution will be through FedEx and 1071 00:46:35,060 --> 00:46:38,710 ups . So I feel very confident in that 1072 00:46:38,710 --> 00:46:40,877 plane . And I think we've got time for 1073 00:46:40,877 --> 00:46:43,700 one last question . Please . Thank you , 1074 00:46:43,710 --> 00:46:45,710 Hassam . Ahmed , you may go ahead . 1075 00:46:45,710 --> 00:46:47,877 Please state your outlet . Yeah , this 1076 00:46:47,877 --> 00:46:50,370 is Issam Mohammed from a F . P . My 1077 00:46:50,370 --> 00:46:52,780 question was , uh since you know , this 1078 00:46:52,790 --> 00:46:56,400 approval seems like a matter of just a 1079 00:46:56,400 --> 00:46:58,567 couple of weeks away . Now , what does 1080 00:46:58,567 --> 00:47:00,456 that mean for those ? Phase three 1081 00:47:00,456 --> 00:47:02,520 trials ? Andi , how you go ahead 1082 00:47:02,520 --> 00:47:04,687 collecting data , do they ? You know , 1083 00:47:04,687 --> 00:47:06,687 since it's approved , people on the 1084 00:47:06,687 --> 00:47:08,742 placebo arm will obviously wanna get 1085 00:47:08,742 --> 00:47:11,740 the actual vaccine . So how does that 1086 00:47:11,750 --> 00:47:14,950 affect how we have , you know , a 1087 00:47:14,960 --> 00:47:17,127 cruise ? More scientific information ? 1088 00:47:17,180 --> 00:47:20,560 Uh , it's still face three then is that 1089 00:47:20,570 --> 00:47:23,080 we want to face for , uh if you could 1090 00:47:23,090 --> 00:47:25,890 talk about that . A little place . So 1091 00:47:25,890 --> 00:47:28,112 very important question . Thank you for 1092 00:47:28,112 --> 00:47:30,223 asking it . And one that we have bean 1093 00:47:30,223 --> 00:47:32,112 discussing at length with all the 1094 00:47:32,112 --> 00:47:34,340 parties involved . First thing to say 1095 00:47:34,340 --> 00:47:36,670 is unfortunately , the rate of 1096 00:47:36,670 --> 00:47:39,610 transmission in the country is such 1097 00:47:40,380 --> 00:47:43,630 that as fighter , for instance , has 1098 00:47:43,630 --> 00:47:46,430 already reached the final analysis . 1099 00:47:46,980 --> 00:47:49,147 You know , the number required for the 1100 00:47:49,147 --> 00:47:52,290 final analysis on announced today . It 1101 00:47:52,290 --> 00:47:55,140 is very likely that moderna will also 1102 00:47:55,140 --> 00:47:57,710 be shortly attaining that number and 1103 00:47:57,710 --> 00:48:00,740 announcing it so sense of strict Oh , 1104 00:48:00,890 --> 00:48:02,900 from the standpoint off efficacy 1105 00:48:02,900 --> 00:48:05,550 analysis that trials will have achieved 1106 00:48:05,550 --> 00:48:09,010 their objective from the standpoint off 1107 00:48:09,010 --> 00:48:11,360 long term follow up into the trials , 1108 00:48:11,710 --> 00:48:14,130 the trials could still generate 1109 00:48:14,130 --> 00:48:17,440 substantial lee important information , 1110 00:48:17,440 --> 00:48:19,607 such as persistence of protection over 1111 00:48:19,607 --> 00:48:23,200 time and safety over time . In that 1112 00:48:23,200 --> 00:48:26,830 regard , we are working with the FDA 1113 00:48:26,830 --> 00:48:29,890 and with the companies on when 1114 00:48:30,870 --> 00:48:34,140 to cross over the placebo group to the 1115 00:48:34,140 --> 00:48:37,870 vaccine and within the placebo group . 1116 00:48:37,880 --> 00:48:40,870 Whether that crossover should happen in 1117 00:48:40,870 --> 00:48:43,010 a staged way , depending on the 1118 00:48:43,010 --> 00:48:45,066 prioritization , for instance , that 1119 00:48:45,066 --> 00:48:47,730 the CDC and the pipe would have put 1120 00:48:47,730 --> 00:48:51,460 forward that will happen . The question 1121 00:48:51,460 --> 00:48:54,780 is mawr . When is it at you a 1122 00:48:54,790 --> 00:48:57,720 approval ? Is it when 1123 00:48:58,170 --> 00:49:00,160 10% of the population has been 1124 00:49:00,160 --> 00:49:04,090 immunized for a particular strata 1125 00:49:04,090 --> 00:49:05,868 of the population that has been 1126 00:49:05,868 --> 00:49:09,030 prioritized ? Is it when the B . L . A . 1127 00:49:09,030 --> 00:49:11,141 Is approved , which actually , from a 1128 00:49:11,141 --> 00:49:13,308 regulatory standpoint , is the trigger 1129 00:49:13,308 --> 00:49:15,530 point ? That's the latest possible . So 1130 00:49:15,530 --> 00:49:17,697 we're talking about a period off maybe 1131 00:49:17,697 --> 00:49:19,830 two or three months , which is 1132 00:49:19,830 --> 00:49:21,830 currently what we project to be the 1133 00:49:21,830 --> 00:49:24,240 time between the EU A and the B . L . A . 1134 00:49:24,240 --> 00:49:26,351 As you know , we always said that the 1135 00:49:26,351 --> 00:49:29,390 EU A was a spit spot , a pit stop 1136 00:49:29,400 --> 00:49:32,790 on the trajectory to a B L A . A . 1137 00:49:33,330 --> 00:49:35,663 And that's the case . So it will happen . 1138 00:49:35,663 --> 00:49:37,886 It will have therefore in impact on our 1139 00:49:37,886 --> 00:49:41,120 city to continue to have control data . 1140 00:49:41,130 --> 00:49:43,640 But it will not impact our capacity toe 1141 00:49:43,650 --> 00:49:45,761 continue to have data . We just would 1142 00:49:45,761 --> 00:49:47,872 not have the control group anymore as 1143 00:49:47,872 --> 00:49:49,817 they will be immunized . There are 1144 00:49:49,817 --> 00:49:52,010 strategies to see extract information 1145 00:49:52,010 --> 00:49:54,120 from that and at that stage is will 1146 00:49:54,120 --> 00:49:57,020 also potentially have impact on 1147 00:49:57,330 --> 00:50:00,220 recruiting subjects in other clinical 1148 00:50:00,220 --> 00:50:02,331 trial . Now I do want to make a point 1149 00:50:02,331 --> 00:50:04,510 here in a plea , frankly , which is 1150 00:50:04,510 --> 00:50:07,370 that we now know that vaccination is 1151 00:50:07,370 --> 00:50:10,110 possible . Not only it's possible , but 1152 00:50:10,110 --> 00:50:12,890 it's incredibly effective . It's very 1153 00:50:12,890 --> 00:50:15,112 likely that the other vaccines that are 1154 00:50:15,112 --> 00:50:18,110 being tested will also be as effective 1155 00:50:18,110 --> 00:50:21,340 or substantially as effective . I would 1156 00:50:21,340 --> 00:50:24,010 really ask for the population off 1157 00:50:24,020 --> 00:50:26,440 people who want to volunteer and help 1158 00:50:26,470 --> 00:50:28,303 to come and participate into the 1159 00:50:28,303 --> 00:50:31,230 clinical trials . A because without 1160 00:50:31,230 --> 00:50:33,341 their participation , it's impossible 1161 00:50:33,341 --> 00:50:35,780 to know whether more vaccines can be 1162 00:50:36,160 --> 00:50:38,271 demonstrated to be effective and safe 1163 00:50:38,480 --> 00:50:40,830 and made available to the population . 1164 00:50:41,110 --> 00:50:43,830 But also there is here . I think , a 1165 00:50:43,840 --> 00:50:45,896 clear potential individual benefit , 1166 00:50:45,896 --> 00:50:48,410 which is , you know , the the way may 1167 00:50:48,410 --> 00:50:50,521 be approved in the middle of December 1168 00:50:50,521 --> 00:50:52,660 or so . And by the time the vaccine 1169 00:50:52,660 --> 00:50:56,020 starts to be laid out , you may as an 1170 00:50:56,020 --> 00:50:58,076 individual , only have access to the 1171 00:50:58,076 --> 00:51:00,420 vaccine in a month and a half or two 1172 00:51:00,420 --> 00:51:02,510 months . If you participate into a 1173 00:51:02,510 --> 00:51:05,310 clinical trial , you have a 50% chance 1174 00:51:05,450 --> 00:51:07,728 to have access to the vaccine tomorrow . 1175 00:51:07,728 --> 00:51:10,120 So both from an altruistic standpoint 1176 00:51:10,410 --> 00:51:12,800 and from a personal standpoint , it 1177 00:51:12,800 --> 00:51:15,680 would be great for people across the 1178 00:51:15,680 --> 00:51:18,020 diversity of populations in the Yusa . 1179 00:51:18,360 --> 00:51:20,880 Please go and participate to clinical 1180 00:51:20,880 --> 00:51:23,500 trial any one of the clinical trials . 1181 00:51:23,500 --> 00:51:26,050 Thank you . Thank you . And thanks to 1182 00:51:26,050 --> 00:51:28,383 the media , for the excellent questions , 1183 00:51:28,383 --> 00:51:31,370 Uh , just to concluding points first , 1184 00:51:31,370 --> 00:51:33,314 as I mentioned , will try toe Have 1185 00:51:33,314 --> 00:51:35,940 these technical briefings occur on a 1186 00:51:35,940 --> 00:51:38,720 regular basis for your benefit ? Uh , 1187 00:51:38,730 --> 00:51:41,260 second , for your readers , your 1188 00:51:41,260 --> 00:51:43,740 listeners , your viewers , I just ask 1189 00:51:43,740 --> 00:51:47,220 you to please keep emphasizing with the 1190 00:51:47,220 --> 00:51:49,164 vaccine news that we have with the 1191 00:51:49,164 --> 00:51:51,164 therapeutic approval that we have . 1192 00:51:51,164 --> 00:51:53,498 There is light at the end of the tunnel , 1193 00:51:53,560 --> 00:51:55,671 but we need people to get there , and 1194 00:51:55,671 --> 00:51:57,782 the way people are going to get there 1195 00:51:57,782 --> 00:51:59,616 is by practicing good individual 1196 00:51:59,616 --> 00:52:01,393 behaviors of washing your hands 1197 00:52:01,393 --> 00:52:03,393 watching your distance Wearing your 1198 00:52:03,393 --> 00:52:03,240 face coverings when you can't watch 1199 00:52:03,240 --> 00:52:05,540 your distance and avoid settings 1200 00:52:05,700 --> 00:52:07,756 especially right now is it's getting 1201 00:52:07,756 --> 00:52:10,170 colder . Indoor settings like crowded 1202 00:52:10,170 --> 00:52:12,350 into restaurants , crowded indoor bars 1203 00:52:12,580 --> 00:52:15,430 or home based settings and doors where 1204 00:52:15,430 --> 00:52:17,541 you're getting together with family , 1205 00:52:17,541 --> 00:52:19,620 friends , neighbors and not watching 1206 00:52:19,630 --> 00:52:21,630 your distance and wearing your face 1207 00:52:21,630 --> 00:52:23,960 coverings letting your guard down . Uh , 1208 00:52:23,970 --> 00:52:26,450 you put yourself at risk . Please do 1209 00:52:26,450 --> 00:52:28,506 those things . Because thanks to the 1210 00:52:28,506 --> 00:52:30,520 great work of these individuals , 1211 00:52:30,530 --> 00:52:32,697 thanks to President Trump's leadership 1212 00:52:32,697 --> 00:52:34,960 of Operation Warp Speed , thanks to the 1213 00:52:34,960 --> 00:52:36,682 world's in America's great bio 1214 00:52:36,682 --> 00:52:38,904 pharmaceutical industry , there is such 1215 00:52:38,904 --> 00:52:41,071 promising hope ahead . We want you all 1216 00:52:41,071 --> 00:52:42,960 to get there so that you can take 1217 00:52:42,960 --> 00:52:45,071 advantage of it . Thank you very much 1218 00:52:45,071 --> 00:52:44,480 for being with us today .