1
00:00:00,140 --> 00:00:02,180
so much for joining our weekly 

2
00:00:02,180 --> 00:00:05,860
operation warp speed briefing . While 

3
00:00:05,860 --> 00:00:07,720
we continue to face concerning 

4
00:00:07,730 --> 00:00:10,300
epidemiological trends across much of 

5
00:00:10,300 --> 00:00:12,380
the country , we also continue 

6
00:00:12,380 --> 00:00:14,540
receiving good news through operation 

7
00:00:14,540 --> 00:00:16,860
warp speed . With Madonna's 

8
00:00:16,860 --> 00:00:19,520
announcement on Monday , two companies 

9
00:00:19,680 --> 00:00:22,190
have now filed you applications with 

10
00:00:22,190 --> 00:00:24,570
the FDA . Out of the three companies 

11
00:00:24,570 --> 00:00:26,514
that have shown promising data for 

12
00:00:26,514 --> 00:00:29,100
efficacy and Phase three trials on top 

13
00:00:29,100 --> 00:00:31,680
of that mawr O . W s supported 

14
00:00:31,680 --> 00:00:33,960
candidates are well on their way in 

15
00:00:33,960 --> 00:00:36,160
that final phase of clinical trials . 

16
00:00:37,020 --> 00:00:39,131
FDA is now scheduled a meeting of its 

17
00:00:39,131 --> 00:00:41,187
Vaccine advisory committee to review 

18
00:00:41,187 --> 00:00:43,353
the Madonna vaccine on December 17th , 

19
00:00:43,740 --> 00:00:45,851
following their meeting on the Pfizer 

20
00:00:45,851 --> 00:00:48,790
vaccine on December the 10th . We also 

21
00:00:48,790 --> 00:00:50,846
learned this morning that the United 

22
00:00:50,846 --> 00:00:52,901
Kingdom has granted authorization to 

23
00:00:52,901 --> 00:00:55,590
the Pfizer vaccine while the FDA 

24
00:00:55,590 --> 00:00:58,490
completes its review . The approval of 

25
00:00:58,490 --> 00:01:01,460
another independent regulatory body 

26
00:01:01,940 --> 00:01:03,970
should give Americans additional 

27
00:01:03,970 --> 00:01:06,750
confidence in the quality of such a 

28
00:01:06,750 --> 00:01:10,020
vaccine . If all goes well as General 

29
00:01:10,020 --> 00:01:12,430
Purna will lay out , that means we can 

30
00:01:12,430 --> 00:01:14,652
make our first shipments of vaccine two 

31
00:01:14,652 --> 00:01:17,270
states this month and we're on track to 

32
00:01:17,270 --> 00:01:20,370
be able to ship enough vaccine for 20 

33
00:01:20,380 --> 00:01:22,602
million Americans before the end of the 

34
00:01:22,602 --> 00:01:25,150
year . Of course , we're all eager to 

35
00:01:25,150 --> 00:01:27,317
have enough supply toe vaccinate every 

36
00:01:27,317 --> 00:01:29,483
American who wants it . And because of 

37
00:01:29,483 --> 00:01:31,690
operation warp speed , we expect to be 

38
00:01:31,700 --> 00:01:35,160
at that point in the spring . Having 

39
00:01:35,160 --> 00:01:37,216
substantial quantities of a safe and 

40
00:01:37,216 --> 00:01:38,882
effective vaccine that's been 

41
00:01:38,882 --> 00:01:41,104
authorized by FDA before the end of the 

42
00:01:41,104 --> 00:01:43,480
year is a remarkable achievement , and 

43
00:01:43,480 --> 00:01:45,647
it will start saving lives very soon , 

44
00:01:46,990 --> 00:01:49,212
as all of you likely know . Yesterday , 

45
00:01:49,212 --> 00:01:51,157
600 held a meeting of its advisory 

46
00:01:51,157 --> 00:01:53,268
committee on immunization Practices , 

47
00:01:53,268 --> 00:01:55,268
which issued recommendations to our 

48
00:01:55,268 --> 00:01:57,390
leadership on how vaccines can be 

49
00:01:57,390 --> 00:01:59,612
effectively and equitably distributed . 

50
00:02:00,510 --> 00:02:02,677
These recommendations will now be used 

51
00:02:02,677 --> 00:02:04,630
by states to develop the best 

52
00:02:04,630 --> 00:02:06,630
prioritization system for their own 

53
00:02:06,630 --> 00:02:08,650
citizens . States have different 

54
00:02:08,650 --> 00:02:10,594
circumstances and are in different 

55
00:02:10,594 --> 00:02:12,761
epidemiological situations , and state 

56
00:02:12,761 --> 00:02:14,761
leaders are in the best position to 

57
00:02:14,761 --> 00:02:16,206
take our general national 

58
00:02:16,206 --> 00:02:19,140
recommendations and translate them into 

59
00:02:19,140 --> 00:02:21,251
more precise guidance for their state 

60
00:02:21,640 --> 00:02:24,520
and its conditions . As we approach the 

61
00:02:24,520 --> 00:02:26,660
vaccine roll out , we're also 

62
00:02:26,660 --> 00:02:28,440
continuing to expand access to 

63
00:02:28,440 --> 00:02:31,190
treatments for Cove in 19 . As of this 

64
00:02:31,190 --> 00:02:33,134
week , we've distributed more than 

65
00:02:33,134 --> 00:02:35,870
157,000 patient courses of two 

66
00:02:35,870 --> 00:02:38,092
authorized antibody products across the 

67
00:02:38,092 --> 00:02:40,600
United States and allocated a total of 

68
00:02:40,600 --> 00:02:44,070
205,000 courses for delivery to states . 

69
00:02:45,010 --> 00:02:47,770
More than 3000 sites are currently 

70
00:02:47,770 --> 00:02:50,070
signed upto offer these treatments . 

71
00:02:50,540 --> 00:02:52,540
We've also launched a pilot program 

72
00:02:52,540 --> 00:02:54,262
that will explore how to reach 

73
00:02:54,262 --> 00:02:56,151
vulnerable populations with these 

74
00:02:56,151 --> 00:02:58,373
treatments and offer the treatments and 

75
00:02:58,373 --> 00:03:00,540
even more convenient locations . As we 

76
00:03:00,540 --> 00:03:03,290
mentioned , Americans need to know that 

77
00:03:03,290 --> 00:03:05,530
this treatment is a possible option for 

78
00:03:05,530 --> 00:03:07,419
patients who are at high risk for 

79
00:03:07,419 --> 00:03:09,980
severe Covad 19 , but who have not been 

80
00:03:09,990 --> 00:03:12,770
hospitalized . That includes all 

81
00:03:12,770 --> 00:03:15,600
Americans over the age of 65 . That's 

82
00:03:15,600 --> 00:03:17,830
the definition we're using in this case 

83
00:03:17,840 --> 00:03:21,430
for risk of severe Covad 19 . Receiving 

84
00:03:21,440 --> 00:03:23,440
this treatment , if you are in that 

85
00:03:23,440 --> 00:03:26,090
category , could help keep you out of 

86
00:03:26,090 --> 00:03:28,460
the hospital , potentially helping to 

87
00:03:28,460 --> 00:03:30,890
save your life . So we want to 

88
00:03:30,890 --> 00:03:32,723
encourage the news media and all 

89
00:03:32,723 --> 00:03:34,890
Americans to spread the word about the 

90
00:03:34,890 --> 00:03:37,001
availability of Covad . 19 treatments 

91
00:03:37,040 --> 00:03:39,520
and one encourage Americans toe start 

92
00:03:39,520 --> 00:03:41,631
playing the role that they'll have an 

93
00:03:41,631 --> 00:03:44,930
eventual vaccine , too . Vaccines will 

94
00:03:44,940 --> 00:03:47,430
only bring this pandemic to an end if 

95
00:03:47,430 --> 00:03:49,590
enough Americans choose to take these 

96
00:03:49,590 --> 00:03:52,880
vaccines . We now have highly promising 

97
00:03:52,890 --> 00:03:54,980
efficacy data that I believe many 

98
00:03:54,980 --> 00:03:57,760
Americans are encouraged by and excited 

99
00:03:57,760 --> 00:04:00,350
about , but I want to encourage 

100
00:04:00,350 --> 00:04:02,406
Americans to get prepared and to get 

101
00:04:02,406 --> 00:04:05,120
educated . Now visit the C . D . C s 

102
00:04:05,120 --> 00:04:07,176
website . Find out Maura , about the 

103
00:04:07,176 --> 00:04:09,009
vaccines we're developing in the 

104
00:04:09,009 --> 00:04:11,120
process they've gone through . If you 

105
00:04:11,120 --> 00:04:13,176
have questions now or have questions 

106
00:04:13,176 --> 00:04:15,231
further down the road , talk to your 

107
00:04:15,231 --> 00:04:16,953
health care provider about the 

108
00:04:16,953 --> 00:04:18,898
importance that safe and effective 

109
00:04:18,898 --> 00:04:20,953
vaccines have tow our own health and 

110
00:04:20,953 --> 00:04:23,064
the health of our communities . These 

111
00:04:23,064 --> 00:04:25,231
vaccine products will be assessed with 

112
00:04:25,231 --> 00:04:27,120
the same rigor that Americans can 

113
00:04:27,120 --> 00:04:29,009
expect when it comes to any other 

114
00:04:29,009 --> 00:04:31,231
vaccine or drug that is reviewed by the 

115
00:04:31,231 --> 00:04:33,570
FDA . As each one of us here has said , 

116
00:04:34,140 --> 00:04:36,307
we're excited to take this vaccine and 

117
00:04:36,307 --> 00:04:38,140
we will encourage our family and 

118
00:04:38,140 --> 00:04:40,196
friends to do so to as appropriate . 

119
00:04:41,320 --> 00:04:43,487
Now , I apologize that I won't be able 

120
00:04:43,487 --> 00:04:45,431
to stay throughout today's Q and A 

121
00:04:45,431 --> 00:04:47,542
because of another media engagement . 

122
00:04:47,542 --> 00:04:49,598
But I will be back next week for the 

123
00:04:49,598 --> 00:04:51,653
full hour . But before I close , I'd 

124
00:04:51,653 --> 00:04:53,730
like toe just make a plea to 

125
00:04:53,730 --> 00:04:57,080
individuals who have had Covad 19 and 

126
00:04:57,080 --> 00:04:59,700
recovered . If you're within three 

127
00:04:59,700 --> 00:05:01,950
months since recovery from co vid 19 , 

128
00:05:02,640 --> 00:05:05,020
we need you to donate plasma over a 

129
00:05:05,020 --> 00:05:07,660
quarter million courses of convalescent 

130
00:05:07,660 --> 00:05:09,890
plasma have been used on your fellow 

131
00:05:09,890 --> 00:05:12,920
Americans to help prevent severe 

132
00:05:12,920 --> 00:05:16,210
consequences from Cove in 19 . We , 

133
00:05:16,210 --> 00:05:17,821
unfortunately , have so many 

134
00:05:17,821 --> 00:05:19,988
individuals who have gotten Cove in 19 

135
00:05:19,988 --> 00:05:22,154
and have recovered now , fortunately , 

136
00:05:22,154 --> 00:05:25,130
But we need donations . Please contact 

137
00:05:25,270 --> 00:05:27,330
your local American Red , cross your 

138
00:05:27,330 --> 00:05:30,530
local American blood bank or go to 

139
00:05:30,530 --> 00:05:32,900
coronavirus gov form or information 

140
00:05:32,910 --> 00:05:34,930
about how you can volunteer to be a 

141
00:05:34,930 --> 00:05:37,750
donor and give the gift of life . With 

142
00:05:37,750 --> 00:05:39,861
that , I will turn things over to the 

143
00:05:39,861 --> 00:05:42,028
extremely capable hands of our leaders 

144
00:05:42,028 --> 00:05:44,361
Dr Moncef Slowey and General Gust Purna , 

145
00:05:44,361 --> 00:05:46,583
who will lead the rest of this briefing 

146
00:05:46,583 --> 00:05:48,750
in the q and A . And I will see you at 

147
00:05:48,750 --> 00:05:50,750
this briefing next week . Thank you 

148
00:05:50,750 --> 00:05:53,083
very much , Doctor . Sloppy . Thank you , 

149
00:05:53,083 --> 00:05:55,680
Mr Secretary . Just a few points to add 

150
00:05:55,810 --> 00:05:57,866
Thio . I think the excellent summary 

151
00:05:57,866 --> 00:06:01,720
that Secretary has provided very , 

152
00:06:01,720 --> 00:06:05,400
very rich week in new data and 

153
00:06:05,400 --> 00:06:09,070
information eso on the Moderna vaccine 

154
00:06:09,070 --> 00:06:11,850
side of things . Uh , the final 

155
00:06:11,850 --> 00:06:15,430
analysis has now bean completed 

156
00:06:15,510 --> 00:06:19,190
with 94.1 efficacy against 

157
00:06:19,200 --> 00:06:21,570
moderate and severe disease . 

158
00:06:22,280 --> 00:06:25,940
Importantly , there were 30 cases of 

159
00:06:25,940 --> 00:06:29,410
severe disease in the trial . All 30 in 

160
00:06:29,410 --> 00:06:31,960
the placebo group . So 100% efficacy . 

161
00:06:32,640 --> 00:06:36,200
There were 7 , 500 some elderly 

162
00:06:36,200 --> 00:06:39,660
people with aged over 65 

163
00:06:40,130 --> 00:06:42,750
and efficacy in that population against 

164
00:06:42,750 --> 00:06:44,660
moderate disease was 

165
00:06:44,670 --> 00:06:48,440
87.1% . And efficacy 

166
00:06:48,450 --> 00:06:50,900
against severe disease was also at 100% 

167
00:06:50,900 --> 00:06:53,650
since there were no cases in the 

168
00:06:53,660 --> 00:06:55,827
vaccine group . I think those are very 

169
00:06:55,827 --> 00:06:59,400
important data to keep in mind this 

170
00:06:59,410 --> 00:07:02,960
exceptionally good data and in fact 

171
00:07:03,200 --> 00:07:06,290
remarkably similar to the data that you 

172
00:07:06,530 --> 00:07:10,100
have already seen coming from with the 

173
00:07:10,100 --> 00:07:13,050
Pfizer vaccine . And obviously , as the 

174
00:07:13,050 --> 00:07:16,920
secretary said , the fact that a 

175
00:07:16,920 --> 00:07:19,760
next IRNA Lee regulatory agency of the 

176
00:07:19,760 --> 00:07:21,600
highest caliber and standards 

177
00:07:21,610 --> 00:07:24,690
equivalent to those of the F d a the U . 

178
00:07:24,690 --> 00:07:28,390
K M A Cherry has approved the 

179
00:07:28,390 --> 00:07:30,612
fighter vaccine . Of course , they have 

180
00:07:30,612 --> 00:07:32,900
not been part and involved in any of 

181
00:07:32,900 --> 00:07:36,510
the politicization that surrounded the 

182
00:07:36,510 --> 00:07:38,840
development off this vaccine , and I 

183
00:07:38,840 --> 00:07:42,070
hope this will be another evidence for 

184
00:07:42,440 --> 00:07:45,200
three American population that data 

185
00:07:45,200 --> 00:07:49,060
with these vaccines are clear , are 

186
00:07:49,280 --> 00:07:51,630
transparent and demonstrate that they 

187
00:07:51,630 --> 00:07:55,600
are effective and safe for use in 

188
00:07:55,600 --> 00:07:58,200
the general population because , as the 

189
00:07:58,200 --> 00:08:00,311
secretary said , vaccines are useless 

190
00:08:00,311 --> 00:08:03,740
if they are not used to 

191
00:08:03,750 --> 00:08:07,070
vaccinate people , I think , 

192
00:08:07,110 --> 00:08:09,870
also really great progress with two 

193
00:08:09,870 --> 00:08:12,490
other vaccines in the pipeline that 

194
00:08:12,490 --> 00:08:15,590
Johnson and Johnson vaccine , which is 

195
00:08:15,600 --> 00:08:18,170
a recombinant human adenovirus 26 

196
00:08:18,740 --> 00:08:22,720
uh , vector has now 

197
00:08:22,720 --> 00:08:25,380
recruited a little bit more than 28,000 

198
00:08:25,380 --> 00:08:28,080
subjects in the face retrial . Now that 

199
00:08:28,080 --> 00:08:30,302
the breakthrough that we hope with this 

200
00:08:30,302 --> 00:08:32,890
vaccine is that it's a one shot vaccine 

201
00:08:33,440 --> 00:08:36,590
with very fast efficacy achieved and 

202
00:08:36,600 --> 00:08:39,650
100% compliance , so to speak , 

203
00:08:40,320 --> 00:08:42,650
since everybody you get one shot , get 

204
00:08:42,650 --> 00:08:44,872
the full vaccination schedule . It will 

205
00:08:44,872 --> 00:08:46,928
be very important , by the way , for 

206
00:08:46,928 --> 00:08:48,983
all Americans who get the Moderna or 

207
00:08:48,983 --> 00:08:51,290
the fighter vaccine to have their first 

208
00:08:51,360 --> 00:08:53,520
vaccine , those and then come back 

209
00:08:53,530 --> 00:08:55,752
either three or four weeks later to get 

210
00:08:55,752 --> 00:08:57,530
their second vaccine . Those to 

211
00:08:57,530 --> 00:08:59,586
complete the immunization schedule . 

212
00:08:59,586 --> 00:09:02,410
The next vaccine in the line is the 

213
00:09:02,410 --> 00:09:05,530
AstraZeneca chimpanzee Adenovirus Life 

214
00:09:05,530 --> 00:09:08,620
Vector vaccine . The face retrial is 

215
00:09:08,620 --> 00:09:11,420
conducted here in the U . S . Under the 

216
00:09:11,420 --> 00:09:14,040
Operation Warp Speed Oversight . So 

217
00:09:14,040 --> 00:09:17,200
it's different trial than the UK Brazil 

218
00:09:17,210 --> 00:09:19,640
trials that have Bean communicated 

219
00:09:19,640 --> 00:09:23,150
about last week is progressing very 

220
00:09:23,150 --> 00:09:25,206
well . We have about 15,000 subjects 

221
00:09:25,206 --> 00:09:28,070
recruited in the trial , both the Anson 

222
00:09:28,070 --> 00:09:31,590
trial and Johnson and Johnson and the 

223
00:09:31,600 --> 00:09:34,140
AstraZeneca trial are likely to 

224
00:09:34,140 --> 00:09:37,340
complete their efficacy requirement , 

225
00:09:37,340 --> 00:09:39,451
which is the number of cases accruing 

226
00:09:39,451 --> 00:09:42,460
in this study somewhere between very 

227
00:09:42,460 --> 00:09:44,780
late in December and the middle of 

228
00:09:44,780 --> 00:09:46,947
January . Given , unfortunately , that 

229
00:09:46,947 --> 00:09:49,400
the pandemic is extremely active and 

230
00:09:49,400 --> 00:09:51,520
there's a lot of transmission in the 

231
00:09:51,520 --> 00:09:54,440
population in closing on the side of 

232
00:09:54,440 --> 00:09:57,060
vaccine . Just like to remind you that 

233
00:09:57,840 --> 00:09:59,951
fortunately , the investments we have 

234
00:09:59,951 --> 00:10:02,370
made in scaling up and starting to 

235
00:10:02,370 --> 00:10:04,760
stockpile manufacturing of the vaccines 

236
00:10:05,140 --> 00:10:08,210
allow us to feel confident that we will 

237
00:10:08,210 --> 00:10:11,530
be able to distribute 20 million enough 

238
00:10:11,530 --> 00:10:14,020
vaccine to immunize 20 million people 

239
00:10:14,350 --> 00:10:16,680
in the U . S . In December . There's 40 

240
00:10:16,680 --> 00:10:19,550
million doses than 30 million people , 

241
00:10:19,610 --> 00:10:23,240
$60 million in January and 50 

242
00:10:23,240 --> 00:10:27,050
million people or 100 million doses in 

243
00:10:27,060 --> 00:10:29,810
March . So between December mid 

244
00:10:29,810 --> 00:10:33,470
December and off in in February 

245
00:10:33,570 --> 00:10:35,780
an end of February , we will have 

246
00:10:36,130 --> 00:10:38,670
potentially immunized 100 million 

247
00:10:38,670 --> 00:10:40,790
people , which is really more or less 

248
00:10:40,790 --> 00:10:43,360
the size off the significant at risk 

249
00:10:43,360 --> 00:10:46,410
population , the elderly , the health 

250
00:10:46,410 --> 00:10:48,632
care workers , the first line workers , 

251
00:10:49,140 --> 00:10:51,740
people with co mobility . I'll close 

252
00:10:51,740 --> 00:10:53,907
there . Of course , be happy to answer 

253
00:10:53,907 --> 00:10:56,073
your questions later on , passed on to 

254
00:10:56,073 --> 00:10:58,073
general partner great Thanks . Dr . 

255
00:10:58,073 --> 00:11:00,100
Slowly has always incredibly well 

256
00:11:00,100 --> 00:11:02,280
informative for us . Uh , all right . 

257
00:11:02,280 --> 00:11:04,280
So , team today , I just wanna talk 

258
00:11:04,280 --> 00:11:07,260
quickly about three things . Allocation , 

259
00:11:07,260 --> 00:11:11,110
update our distribution in support of 

260
00:11:11,110 --> 00:11:13,810
this state plans are our ability to 

261
00:11:13,810 --> 00:11:16,900
empower them to execute their plans and 

262
00:11:16,900 --> 00:11:19,550
then third just to reinforce the 

263
00:11:19,560 --> 00:11:23,120
challenge . My word , uh , to 

264
00:11:23,130 --> 00:11:25,690
secretary a czar's comments at the end 

265
00:11:25,690 --> 00:11:28,560
about learning about vaccines . So , 

266
00:11:28,570 --> 00:11:31,570
you know , first reference allocations 

267
00:11:31,580 --> 00:11:35,160
we have provided the 64 jurisdictions 

268
00:11:35,160 --> 00:11:37,350
with the reminder is the 50 states , 

269
00:11:37,640 --> 00:11:41,000
eight territories and six megacities 

270
00:11:41,240 --> 00:11:45,030
a swell as five federal agencies , with 

271
00:11:45,030 --> 00:11:47,640
their allocations of the vaccines that 

272
00:11:47,640 --> 00:11:49,807
are gonna be available in the month of 

273
00:11:49,807 --> 00:11:52,590
December . What we've done is , we 

274
00:11:52,590 --> 00:11:56,130
believe , for planning purposes on Lee , 

275
00:11:56,140 --> 00:11:59,170
we had to , uh , pick a day , and I've 

276
00:11:59,170 --> 00:12:01,170
coined the phrase snapped the chalk 

277
00:12:01,170 --> 00:12:03,690
line so that we could plan on actual 

278
00:12:03,690 --> 00:12:06,120
doses that will be available . So , for 

279
00:12:06,120 --> 00:12:08,680
example , but week and a half ago , or 

280
00:12:08,680 --> 00:12:11,800
on 20 November through Tiberius , we 

281
00:12:11,800 --> 00:12:14,650
provided the 64 jurisdictions and five 

282
00:12:14,650 --> 00:12:17,440
federal agencies their allocations for 

283
00:12:17,440 --> 00:12:21,060
the Pfizer vaccine of a total of 6.4 

284
00:12:21,060 --> 00:12:23,990
million doses that will be available ah , 

285
00:12:23,990 --> 00:12:27,730
week later on 27 November , we 

286
00:12:27,730 --> 00:12:31,070
provided to 64 allocation jurisdictions 

287
00:12:31,070 --> 00:12:33,440
and five federal agencies . Uh , their 

288
00:12:33,440 --> 00:12:36,380
allocations for the modern A vaccine at 

289
00:12:36,390 --> 00:12:39,030
12.5 million doses that will be 

290
00:12:39,030 --> 00:12:42,730
available again . We are planning to 

291
00:12:42,730 --> 00:12:45,790
be ready when you A is 

292
00:12:45,790 --> 00:12:48,650
approved . It is not about getting in 

293
00:12:48,650 --> 00:12:51,010
front of you . A . It's just making 

294
00:12:51,010 --> 00:12:53,121
sure that we have everything locked . 

295
00:12:53,121 --> 00:12:55,490
So when you a decision comes , 

296
00:12:55,500 --> 00:12:57,840
distribution to the American people 

297
00:12:57,850 --> 00:13:00,620
becomes immediate within 24 hours . 

298
00:13:00,630 --> 00:13:02,630
That's our goal . That's what we're 

299
00:13:02,630 --> 00:13:04,770
striving for on that's what we're 

300
00:13:04,770 --> 00:13:07,900
working to . You can't execute if you 

301
00:13:07,900 --> 00:13:10,610
don't have a plan on . That's what our 

302
00:13:10,610 --> 00:13:13,100
emphasis is . Aziz . We work through 

303
00:13:13,100 --> 00:13:16,920
all that process . Uh , we are going to 

304
00:13:16,920 --> 00:13:19,960
send half the dose is based on 

305
00:13:19,960 --> 00:13:22,570
allocations to the jurisdictions and 

306
00:13:22,570 --> 00:13:25,050
agencies . Uh , because it is a two 

307
00:13:25,050 --> 00:13:27,690
dose regimen as Dr Salah we just talked 

308
00:13:27,690 --> 00:13:30,440
about so half of the allocation will be 

309
00:13:30,440 --> 00:13:32,860
sent out and then 21 days later for 

310
00:13:32,860 --> 00:13:35,960
Pfizer and 28 days later for Madonna , 

311
00:13:36,040 --> 00:13:37,762
we send out the second half of 

312
00:13:37,762 --> 00:13:40,690
allocations , two reasons . One to 

313
00:13:40,690 --> 00:13:44,050
ensure that we don't over administer on , 

314
00:13:44,050 --> 00:13:47,330
that we have the second dose on hand on 

315
00:13:47,330 --> 00:13:49,480
second reason is to make sure that we 

316
00:13:49,480 --> 00:13:51,780
don't overwhelm limited storage 

317
00:13:51,780 --> 00:13:54,630
capability and capacity at the state 

318
00:13:54,630 --> 00:13:57,230
level . We want to augment their plans , 

319
00:13:57,240 --> 00:14:00,360
enable their plans not constrain them 

320
00:14:00,540 --> 00:14:02,700
from the greatest distribution 

321
00:14:02,710 --> 00:14:05,880
capability that they have . We you 

322
00:14:05,890 --> 00:14:08,760
utilize the Tiberius platform that we 

323
00:14:08,760 --> 00:14:11,800
developed right , which is , uh , 

324
00:14:11,810 --> 00:14:14,100
capability . That takes in all the 

325
00:14:14,110 --> 00:14:17,670
informative data from the states , uh , 

326
00:14:17,680 --> 00:14:21,470
hospitals , doctors , offices , uh , 

327
00:14:21,480 --> 00:14:24,990
pharmacies on lee on the specifications 

328
00:14:25,000 --> 00:14:28,750
of vaccine as it is delivered on 

329
00:14:28,750 --> 00:14:31,300
vaccine as it is administered so that 

330
00:14:31,300 --> 00:14:33,950
we can maintain the flow of vaccine to 

331
00:14:33,950 --> 00:14:36,350
the American people . A Z I've talked 

332
00:14:36,350 --> 00:14:38,700
about . Our goal is to distribute 

333
00:14:38,710 --> 00:14:42,430
within 24 hours after eu A on the 

334
00:14:42,440 --> 00:14:44,770
first pushes . Then we want to maintain 

335
00:14:44,780 --> 00:14:47,990
a cadence , a deliberate , uh , 

336
00:14:48,000 --> 00:14:51,710
planned , uh , coordinated cadence of 

337
00:14:51,710 --> 00:14:53,720
delivery of vaccine as it becomes 

338
00:14:53,720 --> 00:14:55,831
available . The only way you could do 

339
00:14:55,831 --> 00:14:57,890
that is if you see yourselves and we 

340
00:14:57,890 --> 00:14:59,890
have to see ourselves from point of 

341
00:14:59,890 --> 00:15:02,670
administration all the way back to 

342
00:15:02,670 --> 00:15:06,090
point of Phil , finish on . In doing 

343
00:15:06,090 --> 00:15:08,310
so , then we can coordinate , 

344
00:15:08,320 --> 00:15:11,010
collaborate , plan together the 

345
00:15:11,020 --> 00:15:13,160
distribution of vaccines down to the 

346
00:15:13,160 --> 00:15:16,750
States . We have requested that the 

347
00:15:16,750 --> 00:15:19,710
state's locking their micro plans for 

348
00:15:19,710 --> 00:15:22,510
final distribution of both vaccines . 

349
00:15:22,510 --> 00:15:25,240
So , for example , this week we've 

350
00:15:25,240 --> 00:15:27,960
asked the state's , uh , in total 

351
00:15:27,960 --> 00:15:29,960
jurisdictions that have their micro 

352
00:15:29,960 --> 00:15:33,960
plans in Tiberius by the end of 

353
00:15:33,960 --> 00:15:37,560
the week or for December . This way we 

354
00:15:37,560 --> 00:15:40,010
can ensure that we understand all the 

355
00:15:40,010 --> 00:15:41,954
places where they want the vaccine 

356
00:15:41,954 --> 00:15:44,066
delivered and at what quantities they 

357
00:15:44,066 --> 00:15:46,177
want the vaccine delivered . And then 

358
00:15:46,177 --> 00:15:48,177
we can coordinate with fights or to 

359
00:15:48,177 --> 00:15:51,690
ensure those boxes are are prepared 

360
00:15:51,770 --> 00:15:54,510
on , ready to be distributed upon you . 

361
00:15:54,510 --> 00:15:56,350
A addresses in the system . 

362
00:15:56,640 --> 00:15:59,990
Coordination with McKesson , the master 

363
00:15:59,990 --> 00:16:03,110
distributor , through FedEx UPS and 

364
00:16:03,110 --> 00:16:05,221
then down to the administration sites 

365
00:16:05,221 --> 00:16:08,360
Really a key effort by everybody . Uh , 

366
00:16:08,370 --> 00:16:10,570
we've asked for the states and 

367
00:16:10,570 --> 00:16:12,570
jurisdictions that have their micro 

368
00:16:12,570 --> 00:16:15,120
plans ready for the modern A vaccine by 

369
00:16:15,120 --> 00:16:18,130
the 11th of December , which allows 

370
00:16:18,130 --> 00:16:20,840
them to do the same planning on In 

371
00:16:20,840 --> 00:16:23,100
theory , what happens is the vaccine 

372
00:16:23,100 --> 00:16:25,030
comes in to where they want . It 

373
00:16:25,030 --> 00:16:27,850
enables their plan for immediate 

374
00:16:27,860 --> 00:16:30,830
administration of the vaccine to the 

375
00:16:30,830 --> 00:16:32,750
priorities that their governor 

376
00:16:33,540 --> 00:16:36,240
establishes at each state . Here's the 

377
00:16:36,240 --> 00:16:39,470
key . The states know their people , 

378
00:16:39,480 --> 00:16:41,760
their populations the best . And as 

379
00:16:41,760 --> 00:16:44,380
they follow through with you , a 

380
00:16:44,390 --> 00:16:47,000
eventually you a guidance and the acid 

381
00:16:47,010 --> 00:16:49,510
guidance that was put out yesterday . 

382
00:16:49,520 --> 00:16:51,800
Then you have leaders taking 

383
00:16:51,800 --> 00:16:54,780
responsibility and directing a pariah 

384
00:16:54,840 --> 00:16:57,730
price priority vaccine into 

385
00:16:57,730 --> 00:17:00,890
administration or shots and arms are 

386
00:17:00,900 --> 00:17:03,910
our responsibility is to enable their 

387
00:17:03,910 --> 00:17:07,720
plan to empower their plan on . That's 

388
00:17:07,720 --> 00:17:09,940
why we've asked for the micro planning 

389
00:17:09,950 --> 00:17:12,010
on the detailed work toe happen 

390
00:17:12,020 --> 00:17:15,130
accordingly . After the initial pushes 

391
00:17:15,130 --> 00:17:18,260
go out for Pfizer and Madonna , then 

392
00:17:18,270 --> 00:17:20,480
every week , right ? Based on 

393
00:17:20,480 --> 00:17:23,110
availability of vaccine as Dr Salah , 

394
00:17:23,110 --> 00:17:26,700
we alluded to 40 million total doses . 

395
00:17:26,710 --> 00:17:29,100
Uh , in December and then January . 

396
00:17:29,100 --> 00:17:32,730
February March . We're going thio 

397
00:17:32,740 --> 00:17:35,810
push allocations as vaccine becomes 

398
00:17:35,810 --> 00:17:38,840
available . We're not waiting for 

399
00:17:38,840 --> 00:17:41,340
cluster of vaccine to be available and 

400
00:17:41,340 --> 00:17:43,440
then push . We wanna have this 

401
00:17:43,440 --> 00:17:46,720
rheumatic cadenced delivery of 

402
00:17:46,720 --> 00:17:49,490
vaccine so that states can best manage 

403
00:17:49,490 --> 00:17:51,710
it to the priorities . Aziz , they've 

404
00:17:51,710 --> 00:17:54,980
developed it . We in visual eyes , uh , 

405
00:17:54,990 --> 00:17:58,310
each week , additional vaccines getting 

406
00:17:58,310 --> 00:18:01,120
out and eventually we just continue to 

407
00:18:01,120 --> 00:18:03,760
build on the amount of people that get 

408
00:18:03,760 --> 00:18:07,720
vaccinated , enhance on our way to 

409
00:18:07,730 --> 00:18:10,330
ending this pandemic 

410
00:18:10,690 --> 00:18:13,800
Jurisdictions and 

411
00:18:14,740 --> 00:18:16,851
the governor's , quite frankly , will 

412
00:18:16,851 --> 00:18:18,962
decide where they wanted to go on the 

413
00:18:18,962 --> 00:18:21,073
end of the day on , we're enabling to 

414
00:18:21,073 --> 00:18:24,500
that end , So I just would reinforce in 

415
00:18:24,500 --> 00:18:27,040
this point here allocations made 

416
00:18:27,050 --> 00:18:29,800
jurisdictions planning . We're trying 

417
00:18:29,810 --> 00:18:33,130
to enable them thio work through their 

418
00:18:33,130 --> 00:18:35,900
priorities . Thio best take care of the 

419
00:18:35,900 --> 00:18:37,760
people of their jurisdictions 

420
00:18:37,770 --> 00:18:40,660
accordingly . Second , I'd like to talk 

421
00:18:40,660 --> 00:18:43,940
to you about , um how we're working to 

422
00:18:43,940 --> 00:18:47,240
empower the states on make sure that 

423
00:18:47,240 --> 00:18:49,740
they are well informed of all the 

424
00:18:49,740 --> 00:18:51,910
processes that we have available . I 

425
00:18:51,910 --> 00:18:54,660
just want to commend the c d . C for 

426
00:18:54,660 --> 00:18:56,938
the remarkable work that they're doing . 

427
00:18:56,938 --> 00:18:59,790
These , um , the's great leaders , 

428
00:18:59,800 --> 00:19:02,170
these very , very talented , 

429
00:19:03,040 --> 00:19:06,750
uh , professionals . Well trained 

430
00:19:06,760 --> 00:19:10,190
experts in this field of distribution 

431
00:19:10,200 --> 00:19:12,510
have really set up an elaborate 

432
00:19:12,510 --> 00:19:15,690
coordination on collaboration effort 

433
00:19:15,690 --> 00:19:19,650
with the states . They run daily weekly 

434
00:19:19,660 --> 00:19:22,750
meetings . They work through detailed 

435
00:19:22,760 --> 00:19:25,310
execution of plans . They make 

436
00:19:25,320 --> 00:19:27,440
recommendations on how the best 

437
00:19:27,440 --> 00:19:30,900
facilities eyes on operationalize the 

438
00:19:30,900 --> 00:19:33,480
distribution on . Then they figure out 

439
00:19:33,480 --> 00:19:35,980
ways to enable the state and 

440
00:19:35,980 --> 00:19:39,420
jurisdiction plans really well done by 

441
00:19:39,420 --> 00:19:41,630
the CDC . And I'm pretty proud to be a 

442
00:19:41,630 --> 00:19:43,860
part of the collaboration with them . 

443
00:19:44,240 --> 00:19:46,590
Second , we worked a very elaborate 

444
00:19:46,600 --> 00:19:48,550
update , uh , in talking to the 

445
00:19:48,550 --> 00:19:52,150
governor's , um either through HHS 

446
00:19:52,160 --> 00:19:55,330
or up through Vice President Pence's , 

447
00:19:55,340 --> 00:19:57,960
um , sessions with them , but also , 

448
00:19:57,960 --> 00:20:00,570
through individual phone calls to the 

449
00:20:00,570 --> 00:20:03,260
governors to their health coordinators , 

450
00:20:03,440 --> 00:20:05,840
A to the leader senior leadership level 

451
00:20:05,840 --> 00:20:08,007
to make sure we're answering questions 

452
00:20:08,007 --> 00:20:10,190
in a timely manner on getting them 

453
00:20:10,190 --> 00:20:13,930
solutions to their problems again . We 

454
00:20:13,930 --> 00:20:16,210
want to enable and empower the 

455
00:20:16,210 --> 00:20:19,390
jurisdictions Thio execute their 

456
00:20:19,390 --> 00:20:22,900
plans . That is our sole goal our 

457
00:20:22,900 --> 00:20:25,360
responsibility to do . And we've worked 

458
00:20:25,370 --> 00:20:27,880
extremely hard . Uh , two things I've 

459
00:20:27,880 --> 00:20:29,990
coached people on over over 

460
00:20:29,990 --> 00:20:33,610
communication , uh , is an asset to to 

461
00:20:33,610 --> 00:20:36,970
our execution on then . Second , you 

462
00:20:36,970 --> 00:20:39,790
know , you got to do the virtual 

463
00:20:39,800 --> 00:20:43,000
circulation , right ? We have to see 

464
00:20:43,000 --> 00:20:45,222
what the governors and their staffs are 

465
00:20:45,222 --> 00:20:47,222
seeing so we can best enable them . 

466
00:20:47,222 --> 00:20:49,340
Clearly , one of the one of their 

467
00:20:49,340 --> 00:20:51,451
concerns that they're working through 

468
00:20:51,451 --> 00:20:53,451
is how to do , uh , nursing homes , 

469
00:20:53,451 --> 00:20:56,430
long , long term health care facilities , 

470
00:20:56,440 --> 00:20:58,980
right in the C . D . C . And O . W s 

471
00:20:58,980 --> 00:21:01,830
collaborated really worked a very 

472
00:21:01,840 --> 00:21:05,300
extensive plan . Uh , in collaboration 

473
00:21:05,300 --> 00:21:08,740
with CVS Walgreen on other private 

474
00:21:08,740 --> 00:21:12,580
pharmacies to enable state governor 

475
00:21:12,580 --> 00:21:15,210
plans on getting to those , uh , 

476
00:21:15,220 --> 00:21:17,690
facilities . How do we get it out to 

477
00:21:17,690 --> 00:21:20,050
them ? How do we make sure that we're 

478
00:21:20,050 --> 00:21:22,700
there to administer to them on ? I am 

479
00:21:22,700 --> 00:21:26,700
incredibly confident that thes private 

480
00:21:26,710 --> 00:21:29,820
public partnerships are ready toe 

481
00:21:29,830 --> 00:21:32,100
execute based on the governor's 

482
00:21:32,100 --> 00:21:35,410
priorities and plans to do so on . And 

483
00:21:35,420 --> 00:21:38,090
I am excited . Uh , toe watch that to 

484
00:21:38,090 --> 00:21:41,000
get operationalized the last thing I'll 

485
00:21:41,000 --> 00:21:42,980
leave you with in touching with 

486
00:21:42,990 --> 00:21:45,480
Secretary is ours . Comments on 

487
00:21:45,480 --> 00:21:48,180
reinforcing Doctor Salahi's comments on 

488
00:21:48,190 --> 00:21:50,560
really the great potential and efficacy 

489
00:21:50,560 --> 00:21:53,560
of the vaccine is as we go forward . 

490
00:21:53,590 --> 00:21:56,370
Vaccine is only good as it being 

491
00:21:56,370 --> 00:21:59,110
administered to the American people on 

492
00:21:59,110 --> 00:22:02,840
DSO . I just ask everybody to to 

493
00:22:02,840 --> 00:22:05,560
really educate yourself , right ? 

494
00:22:05,570 --> 00:22:08,310
Figure out you know what you want to do 

495
00:22:08,310 --> 00:22:10,900
as an individual , but be informed in 

496
00:22:10,900 --> 00:22:14,110
your process . Don't allow one headline 

497
00:22:14,120 --> 00:22:16,650
to determine what you're going to do . 

498
00:22:16,660 --> 00:22:18,438
Uh , there is so much available 

499
00:22:18,438 --> 00:22:21,400
information on I just encourage 

500
00:22:21,400 --> 00:22:25,100
everybody , uh , as an individual . Ah . 

501
00:22:25,100 --> 00:22:28,320
Community on , of course , is a part of 

502
00:22:28,320 --> 00:22:30,850
our great nation to really inform 

503
00:22:30,850 --> 00:22:33,350
yourself and then make the decision 

504
00:22:33,360 --> 00:22:36,260
that is best for you on your family . 

505
00:22:36,270 --> 00:22:38,710
And so , with that slow , I think take 

506
00:22:38,710 --> 00:22:42,470
questions , her questions . Thank you , 

507
00:22:42,470 --> 00:22:44,526
operator . Well , can open it up for 

508
00:22:44,526 --> 00:22:46,803
questions now , on a friendly reminder , 

509
00:22:46,803 --> 00:22:48,970
uh , to remove your friends that we're 

510
00:22:48,970 --> 00:22:48,420
asking a question , please state your 

511
00:22:48,420 --> 00:22:50,476
name and publication and please keep 

512
00:22:50,476 --> 00:22:52,642
your questions short as possible so we 

513
00:22:52,642 --> 00:22:54,809
can get to us many questions as we can 

514
00:22:54,809 --> 00:22:56,864
in the time that we have alternative 

515
00:22:56,864 --> 00:23:00,210
routine . Operator . Thank you . We 

516
00:23:00,210 --> 00:23:02,377
will not begin the question and answer 

517
00:23:02,377 --> 00:23:04,432
session . If you would like to ask a 

518
00:23:04,432 --> 00:23:06,377
question , please Press star one , 

519
00:23:06,377 --> 00:23:08,266
please . I meet your phone . Ever 

520
00:23:08,266 --> 00:23:10,377
important first and last name as well 

521
00:23:10,377 --> 00:23:12,488
as your organization . Clearly , when 

522
00:23:12,488 --> 00:23:14,543
prompted to withdraw your question , 

523
00:23:14,543 --> 00:23:16,599
you may press start to once again at 

524
00:23:16,599 --> 00:23:18,766
this time . If you would like to ask a 

525
00:23:18,766 --> 00:23:20,932
question , please press star one . And 

526
00:23:20,932 --> 00:23:23,210
our first question is from Meg . Carol , 

527
00:23:23,210 --> 00:23:24,932
If you won't mind staying your 

528
00:23:24,932 --> 00:23:26,877
organization , your line is open . 

529
00:23:26,877 --> 00:23:29,350
Thank you . It's Meg's around with CNBC . 

530
00:23:29,360 --> 00:23:31,527
Um , Dr Sally , I was wondering if you 

531
00:23:31,527 --> 00:23:33,471
could just sort of go back through 

532
00:23:33,471 --> 00:23:35,527
those allocation numbers per month , 

533
00:23:35,527 --> 00:23:37,527
but you laid out . I wanted to make 

534
00:23:37,527 --> 00:23:39,582
sure we we got it right . You know , 

535
00:23:39,582 --> 00:23:41,416
the 40 million doses December 60 

536
00:23:41,416 --> 00:23:44,250
million January 100 million in February . 

537
00:23:44,260 --> 00:23:46,240
Is that just fighter and modernist 

538
00:23:46,240 --> 00:23:48,240
vaccines ? And then to follow up on 

539
00:23:48,240 --> 00:23:50,296
something general partner was saying 

540
00:23:50,296 --> 00:23:52,407
with only half the dose is being sent 

541
00:23:52,407 --> 00:23:54,351
out and then the second half being 

542
00:23:54,351 --> 00:23:56,518
followed up to ensure proper storage . 

543
00:23:56,518 --> 00:23:58,573
What is the right way for us to talk 

544
00:23:58,573 --> 00:24:00,796
about the number of people who will get 

545
00:24:00,796 --> 00:24:03,018
their first shot with these doses ? You 

546
00:24:03,018 --> 00:24:05,500
know , in the 1st 6.4 million ? Is that 

547
00:24:05,510 --> 00:24:07,680
6.4 million people getting their first 

548
00:24:07,740 --> 00:24:09,851
shot ? We often divide by two and say 

549
00:24:09,851 --> 00:24:12,073
it's enough for 3.2 million people . So 

550
00:24:12,073 --> 00:24:14,129
what is the terminology for us to be 

551
00:24:14,129 --> 00:24:17,130
using ? Thank you , Mike for questions . 

552
00:24:17,130 --> 00:24:19,352
So the numbers were indeed , and I used 

553
00:24:19,352 --> 00:24:21,770
the number off people to be vaccinated 

554
00:24:22,440 --> 00:24:25,000
with the complete those of vaccines or 

555
00:24:25,010 --> 00:24:28,260
two shots . 20 million in December , 

556
00:24:28,740 --> 00:24:32,610
30 million in January , 50 million in 

557
00:24:32,610 --> 00:24:35,000
February . And that's with the fighter 

558
00:24:35,000 --> 00:24:37,220
and modern A vaccine . There is a 

559
00:24:37,220 --> 00:24:39,960
chance that we may have mawr vaccine . 

560
00:24:39,960 --> 00:24:41,990
Those is available in February , 

561
00:24:42,700 --> 00:24:44,660
particularly with the young sons 

562
00:24:44,660 --> 00:24:48,590
vaccine . If the Jenson vaccine gets in 

563
00:24:48,590 --> 00:24:50,868
emergency use , authorization approved . 

564
00:24:50,910 --> 00:24:52,830
So , as I said , it's possible 

565
00:24:52,830 --> 00:24:54,663
depending on the number of cases 

566
00:24:54,663 --> 00:24:57,170
accruing that that face retrial 

567
00:24:57,170 --> 00:24:59,740
completes its efficacy endpoint during 

568
00:24:59,740 --> 00:25:02,120
the month of January . So there may be 

569
00:25:02,120 --> 00:25:04,231
a scenario we could have a little bit 

570
00:25:04,231 --> 00:25:06,398
mawr with a one shot vaccine with that 

571
00:25:06,398 --> 00:25:08,453
vaccine one those equal , one person 

572
00:25:08,453 --> 00:25:10,676
immunized . My recommendation is to use 

573
00:25:10,676 --> 00:25:12,842
a number of people immunized . I think 

574
00:25:12,842 --> 00:25:15,270
it's it's more factual . I mean more 

575
00:25:15,270 --> 00:25:16,660
really two people . 

576
00:25:20,640 --> 00:25:23,290
Our next question is from John Collins 

577
00:25:23,300 --> 00:25:25,356
with Science magazine . Your line is 

578
00:25:25,356 --> 00:25:28,970
open . I am . This is I am 

579
00:25:29,740 --> 00:25:32,920
you pray , Doctor slowly and , um , 

580
00:25:32,930 --> 00:25:35,750
secretariats are praised The vision by 

581
00:25:35,750 --> 00:25:39,630
the HR A tow , either . But the Iemma 

582
00:25:39,640 --> 00:25:41,980
in Europe and many European leaders 

583
00:25:41,990 --> 00:25:44,270
have early criticized that is , being 

584
00:25:44,280 --> 00:25:46,800
hasty on our own . FDA process 

585
00:25:46,810 --> 00:25:49,660
obviously is transparent and slower , 

586
00:25:50,220 --> 00:25:52,276
meant to build confidence . I wonder 

587
00:25:52,276 --> 00:25:55,130
whether you want to clarify thing that 

588
00:25:55,130 --> 00:25:57,019
others are heavily criticizing in 

589
00:25:57,019 --> 00:26:00,880
Europe . But , 

590
00:26:00,890 --> 00:26:04,660
um , we don't know exactly how the 

591
00:26:04,670 --> 00:26:08,000
process has taken place . A . Z . You 

592
00:26:08,000 --> 00:26:11,560
know , we stay totally away from the 

593
00:26:11,560 --> 00:26:13,671
regulatory process , whether with the 

594
00:26:13,671 --> 00:26:16,730
FDA or with others . What we understand 

595
00:26:16,730 --> 00:26:18,890
is that there have bean rolling 

596
00:26:18,890 --> 00:26:22,750
submissions where different parts of 

597
00:26:22,750 --> 00:26:26,230
the file to be authorized have been 

598
00:26:26,230 --> 00:26:28,397
submitted at different times . Point , 

599
00:26:28,840 --> 00:26:31,820
I would speculate that fighter 

600
00:26:31,820 --> 00:26:34,900
manufacturing CMC part of the file must 

601
00:26:34,900 --> 00:26:37,060
have been filed quite a while ago . 

602
00:26:37,640 --> 00:26:40,850
Andi therefore potentially 

603
00:26:41,240 --> 00:26:44,650
the the review has focused on the 

604
00:26:44,660 --> 00:26:47,090
clinical side , the rest of it having 

605
00:26:47,100 --> 00:26:49,220
been done earlier . But frankly , I 

606
00:26:49,220 --> 00:26:51,620
cannot commit . What I would agree with 

607
00:26:51,620 --> 00:26:53,620
you completely is . We know the FDA 

608
00:26:53,620 --> 00:26:56,700
process . It's a completely transparent 

609
00:26:56,710 --> 00:26:58,670
process , with independent experts 

610
00:26:58,670 --> 00:27:00,670
commenting and asking questions and 

611
00:27:00,840 --> 00:27:04,470
recommending or advising the agency , 

612
00:27:04,820 --> 00:27:07,490
and we will imminently be going through 

613
00:27:07,490 --> 00:27:09,810
it . I know personally from my 

614
00:27:09,810 --> 00:27:11,870
experience in my previous life life 

615
00:27:11,870 --> 00:27:14,730
that the HR is an extremely high grade 

616
00:27:14,740 --> 00:27:17,710
agency . In fact , within the Iemma 

617
00:27:17,710 --> 00:27:21,310
before they left it there , certainly 

618
00:27:21,310 --> 00:27:23,990
the the scientific engine , the U . K 

619
00:27:23,990 --> 00:27:26,780
and the pie German part of the agency . 

620
00:27:27,540 --> 00:27:30,280
Thank you . Yeah . 

621
00:27:31,540 --> 00:27:33,600
Our next question is from Zachary 

622
00:27:33,600 --> 00:27:35,550
Brennan . Um , please state your 

623
00:27:35,550 --> 00:27:37,661
organization , if you may . Your line 

624
00:27:37,661 --> 00:27:40,710
is open . Thanks for taking my question 

625
00:27:40,720 --> 00:27:44,100
back from Politico . So , uh , General 

626
00:27:44,100 --> 00:27:46,960
Purna mentioned earlier that about 21 

627
00:27:46,960 --> 00:27:49,071
jurisdictions still haven't signed on 

628
00:27:49,071 --> 00:27:51,238
to these data user agreements . What's 

629
00:27:51,238 --> 00:27:53,349
gonna happen with those jurisdictions 

630
00:27:53,349 --> 00:27:55,293
if they ultimately don't sign onto 

631
00:27:55,293 --> 00:27:57,404
those on , then can you talk a little 

632
00:27:57,404 --> 00:27:59,627
bit about why certain states air saying 

633
00:27:59,627 --> 00:28:01,738
the vaccine allocations they're a lot 

634
00:28:01,738 --> 00:28:03,849
smaller than what they originally had 

635
00:28:03,849 --> 00:28:07,730
thought . So yes , it's So first 

636
00:28:07,730 --> 00:28:11,680
question , we're down to 17 . We 

637
00:28:11,680 --> 00:28:14,240
are really getting to the last dot the 

638
00:28:14,240 --> 00:28:16,560
I cross the t and I feel very 

639
00:28:16,560 --> 00:28:19,130
confidence that confident that all the 

640
00:28:19,130 --> 00:28:21,470
jurisdictions will have their data use 

641
00:28:21,470 --> 00:28:23,690
agreements in , uh and everything will 

642
00:28:23,690 --> 00:28:26,100
be alright . Uh , to your second 

643
00:28:26,100 --> 00:28:28,610
question , what we're doing is is 

644
00:28:28,620 --> 00:28:30,620
instead of waiting until the end of 

645
00:28:30,620 --> 00:28:32,731
December , where we know we'll have a 

646
00:28:32,731 --> 00:28:34,898
cumulative amount of vaccine Is doctor 

647
00:28:34,898 --> 00:28:37,009
slowly mentioned and I reinforce that 

648
00:28:37,009 --> 00:28:39,520
40 million doses ? Um , what we're 

649
00:28:39,520 --> 00:28:42,530
doing is at the time of we speculate 

650
00:28:42,540 --> 00:28:45,600
you a is gonna occur . The doses that 

651
00:28:45,600 --> 00:28:48,090
will be available a 6.4 million for 

652
00:28:48,090 --> 00:28:51,530
Pfizer and 12.5 for Moderna . And 

653
00:28:51,530 --> 00:28:53,252
that's what we did the initial 

654
00:28:53,252 --> 00:28:56,260
allocation based on on DSO . That push 

655
00:28:56,260 --> 00:28:58,980
will go out based on those allocations . 

656
00:28:58,990 --> 00:29:01,870
But every day that goes by after the 

657
00:29:01,870 --> 00:29:05,370
initial push , additional vaccines come 

658
00:29:05,370 --> 00:29:07,314
off the shelf because they've been 

659
00:29:07,314 --> 00:29:10,830
certified , um , and approved for 

660
00:29:10,840 --> 00:29:13,660
distribution and administration . Hence 

661
00:29:13,670 --> 00:29:15,780
what ? I talked about the continuous 

662
00:29:15,780 --> 00:29:19,310
cadence of delivery of vaccine , uh , 

663
00:29:19,320 --> 00:29:21,431
going out to the American people . So 

664
00:29:21,431 --> 00:29:23,570
it's not a one and done . It's a 

665
00:29:23,580 --> 00:29:26,520
initial push and then a continuous 

666
00:29:26,530 --> 00:29:30,030
uh , cadenced flow of 

667
00:29:30,030 --> 00:29:32,720
vaccine , uh , for planning and 

668
00:29:32,720 --> 00:29:35,870
coordination and execution . Thank you . 

669
00:29:39,340 --> 00:29:41,350
Our next question is from Stephanie 

670
00:29:41,360 --> 00:29:43,780
Ebbs with ABC News . Your line is open . 

671
00:29:45,340 --> 00:29:47,507
Thank you . Something upstream , ABC . 

672
00:29:47,507 --> 00:29:49,618
I wanted to follow up on that general 

673
00:29:49,618 --> 00:29:51,673
per note . When you're talking about 

674
00:29:51,673 --> 00:29:53,784
the continued cadence of deliveries , 

675
00:29:53,784 --> 00:29:56,007
how will the amount in those deliveries 

676
00:29:56,007 --> 00:29:58,480
be allocated on ? But is it correct to 

677
00:29:58,490 --> 00:30:00,660
say that then each subsequent delivery 

678
00:30:00,660 --> 00:30:02,880
would be followed by a delivery of the 

679
00:30:02,880 --> 00:30:05,970
same amount 21 or 23 days later ? 

680
00:30:06,440 --> 00:30:09,310
So what we're doing is through Tiberius , 

681
00:30:09,320 --> 00:30:11,670
the program that we established , which 

682
00:30:11,670 --> 00:30:14,610
is located at each of the jurisdictions . 

683
00:30:14,620 --> 00:30:17,590
Um , we're establishing the available 

684
00:30:17,600 --> 00:30:21,490
doses of vaccine Thio each state on DSO . 

685
00:30:21,490 --> 00:30:24,150
They get to see that the Tiberius 

686
00:30:24,150 --> 00:30:26,830
allows them to see the allocation 

687
00:30:26,840 --> 00:30:28,896
allows them to go through a planning 

688
00:30:28,896 --> 00:30:31,170
process of where they would like toa 

689
00:30:31,180 --> 00:30:34,210
have the vaccine to go to manipulate it 

690
00:30:34,210 --> 00:30:36,099
so that they can see , you know , 

691
00:30:36,099 --> 00:30:38,154
impact of the dose is going to those 

692
00:30:38,154 --> 00:30:40,210
locations . And then once it finally 

693
00:30:40,210 --> 00:30:43,760
approved , they hit sand on . That is 

694
00:30:43,760 --> 00:30:46,450
how we distribute so quick . Answer to 

695
00:30:46,450 --> 00:30:49,230
your question is through Tiberius open 

696
00:30:49,230 --> 00:30:51,770
and transparent with each jurisdiction 

697
00:30:51,780 --> 00:30:54,500
as allocations become available . And 

698
00:30:54,500 --> 00:30:56,722
then the second part of your question , 

699
00:30:56,722 --> 00:30:58,722
I apologize . I don't remember it . 

700
00:31:03,240 --> 00:31:05,351
Anybody help me on that one . I can't 

701
00:31:05,351 --> 00:31:07,518
remember because it was the allocation 

702
00:31:07,518 --> 00:31:09,573
in states how we are located . Those 

703
00:31:09,573 --> 00:31:12,140
two have said , Yeah . So Perata . 

704
00:31:14,640 --> 00:31:17,260
Oh , I apologize . I apologize . Thank 

705
00:31:17,260 --> 00:31:19,038
you . So the second part of the 

706
00:31:19,038 --> 00:31:21,260
question was is , are we gonna hold the 

707
00:31:21,260 --> 00:31:22,920
second dose ? Uh , for every 

708
00:31:22,920 --> 00:31:24,976
distribution as we go forward in the 

709
00:31:24,976 --> 00:31:27,790
cadence . And the answer is yes . Our 

710
00:31:27,800 --> 00:31:31,670
our responsibility is to make 

711
00:31:31,670 --> 00:31:34,200
sure that we have both doses in hand 

712
00:31:34,210 --> 00:31:36,630
before we send the first dose out . 

713
00:31:36,640 --> 00:31:38,807
That way , we're always confident that 

714
00:31:38,807 --> 00:31:41,084
the second dose will be available . Um , 

715
00:31:41,084 --> 00:31:43,820
for everybody a z get administered 

716
00:31:43,820 --> 00:31:46,280
their shots over . Thank you 

717
00:31:47,140 --> 00:31:51,060
over . Our next 

718
00:31:51,060 --> 00:31:54,630
question is from Steve House . In with 

719
00:31:54,640 --> 00:31:57,910
Bio Century , your line is open . I I 

720
00:31:57,910 --> 00:32:00,590
wanted to ask if there any systems in 

721
00:32:00,590 --> 00:32:03,510
place for tracking outcomes for people 

722
00:32:03,510 --> 00:32:05,650
who are vaccinated . Are there any 

723
00:32:05,650 --> 00:32:08,260
registries or other systems for 

724
00:32:08,760 --> 00:32:11,020
determining what the outcomes are on an 

725
00:32:11,020 --> 00:32:14,630
ongoing basis ? Yes . So the FDA and 

726
00:32:14,630 --> 00:32:16,970
the CDC are working very closely 

727
00:32:16,970 --> 00:32:20,280
together to put together a very active , 

728
00:32:20,280 --> 00:32:22,580
far Michael vigilance and surveillance 

729
00:32:22,580 --> 00:32:25,680
system , using various very large 

730
00:32:25,680 --> 00:32:29,210
databases currently in use on 

731
00:32:29,220 --> 00:32:31,510
integrating all the data from those 

732
00:32:31,510 --> 00:32:34,830
databases with potentially 

733
00:32:34,830 --> 00:32:37,360
frequencies off assessment off events 

734
00:32:37,790 --> 00:32:39,900
as frequently as every other day , 

735
00:32:39,900 --> 00:32:42,700
which , frankly , gets even closer than 

736
00:32:42,700 --> 00:32:45,380
what happens in a clinical trial . On 

737
00:32:45,390 --> 00:32:47,540
that , the covered population will be 

738
00:32:47,540 --> 00:32:51,020
very , uh , very large . 

739
00:32:51,020 --> 00:32:54,250
Include large elderly 

740
00:32:54,250 --> 00:32:58,220
populations large , uh , V 

741
00:32:58,220 --> 00:33:02,020
a related population Andi on 

742
00:33:02,020 --> 00:33:04,187
global population through ah , various 

743
00:33:04,187 --> 00:33:07,590
insurance carrier . So I think a very 

744
00:33:07,590 --> 00:33:09,470
extensive plan . 

745
00:33:12,040 --> 00:33:13,040
Next question . 

746
00:33:16,040 --> 00:33:18,700
Our next question is from Kevin Brown 

747
00:33:18,700 --> 00:33:22,040
with Fox News . Your line is open . Hi . 

748
00:33:22,040 --> 00:33:24,096
Good afternoon . Evan Brown with Fox 

749
00:33:24,096 --> 00:33:26,720
News . Um , if you if both gentlemen 

750
00:33:26,720 --> 00:33:30,450
could once again , uh , talk about the 

751
00:33:30,840 --> 00:33:33,370
whatever pushes being done from a 

752
00:33:33,380 --> 00:33:36,160
messaging standpoint to encourage as 

753
00:33:36,160 --> 00:33:39,690
many people to , um , get vaccinated to 

754
00:33:39,700 --> 00:33:41,920
quell their fears , uh , and really 

755
00:33:41,920 --> 00:33:44,760
inspire them to take this action . Um , 

756
00:33:44,760 --> 00:33:46,880
And on the back end of that , how do 

757
00:33:46,880 --> 00:33:48,880
people know , Or how will people be 

758
00:33:48,880 --> 00:33:50,824
able to know ? We're talking about 

759
00:33:50,824 --> 00:33:53,460
general population now , um , when they 

760
00:33:53,460 --> 00:33:55,571
would be able to get a vaccine either 

761
00:33:55,571 --> 00:33:57,516
at their doctor's office or corner 

762
00:33:57,516 --> 00:34:01,350
drugstore . So I think it is . Every 

763
00:34:02,140 --> 00:34:05,660
experts frankly duty today 

764
00:34:06,240 --> 00:34:08,730
as we get Mawr and Mawr exposed to the 

765
00:34:08,730 --> 00:34:11,740
data , which will become totally public 

766
00:34:11,750 --> 00:34:14,580
at the time off . FDA review with the 

767
00:34:14,580 --> 00:34:17,570
verb pack to look into that data 

768
00:34:18,640 --> 00:34:22,390
to put aside their preset opinions and 

769
00:34:22,390 --> 00:34:26,380
anchor their comments into the 

770
00:34:26,380 --> 00:34:30,250
data and the science . I really believe 

771
00:34:30,250 --> 00:34:31,850
that through that process , 

772
00:34:33,740 --> 00:34:36,450
thousands of experts are able to look 

773
00:34:36,450 --> 00:34:38,520
into this data and comment on it and 

774
00:34:38,530 --> 00:34:41,550
talk about it , too . The people that 

775
00:34:41,550 --> 00:34:44,290
they interact with because I think what 

776
00:34:44,290 --> 00:34:46,530
I what I say is for everybody to keep 

777
00:34:46,540 --> 00:34:49,420
let's keep our ears open in our mind , 

778
00:34:49,810 --> 00:34:52,370
receptive to the information that the 

779
00:34:52,370 --> 00:34:54,650
factual information on the performance 

780
00:34:54,650 --> 00:34:56,706
of the vaccine , both its safety and 

781
00:34:56,706 --> 00:34:59,720
it's efficacy and then make our 

782
00:34:59,730 --> 00:35:02,008
judgment whether we will use it or not . 

783
00:35:02,540 --> 00:35:04,670
And the experts across the country 

784
00:35:04,670 --> 00:35:07,130
should should take accountability off 

785
00:35:07,140 --> 00:35:09,196
participating into that process that 

786
00:35:09,196 --> 00:35:12,130
translate that's scientific data for 

787
00:35:12,130 --> 00:35:14,241
everybody to be able to understand it 

788
00:35:14,740 --> 00:35:16,962
in terms of availability of vaccine . I 

789
00:35:16,962 --> 00:35:19,270
think very early into the distribution 

790
00:35:19,270 --> 00:35:21,720
process , it's likely that the vaccines 

791
00:35:21,720 --> 00:35:24,520
will be going to the subjects who are 

792
00:35:24,520 --> 00:35:27,700
going to receive them , Asl Ong as 

793
00:35:27,710 --> 00:35:29,920
surely I would say in the month of 

794
00:35:29,920 --> 00:35:32,740
December and probably early January . 

795
00:35:32,750 --> 00:35:34,870
That's what we're talking about . I 

796
00:35:34,870 --> 00:35:36,981
think we will start communicating and 

797
00:35:36,981 --> 00:35:39,037
specifically and maybe general panic 

798
00:35:39,037 --> 00:35:41,100
and comment further on that in each 

799
00:35:41,100 --> 00:35:43,000
state , there should be active 

800
00:35:43,000 --> 00:35:45,830
communication as vaccines now become 

801
00:35:46,020 --> 00:35:48,480
available for people to go to the 

802
00:35:48,480 --> 00:35:51,750
vaccine Walgreen or CVS or elsewhere or 

803
00:35:51,760 --> 00:35:54,470
or their physician on be administered 

804
00:35:54,470 --> 00:35:58,050
the vaccine . Yeah , so just Thio just 

805
00:35:58,050 --> 00:36:00,161
take off where doctors are We left is 

806
00:36:00,161 --> 00:36:03,540
even this session here with you , right ? 

807
00:36:03,550 --> 00:36:06,470
Asking questions and getting the fax 

808
00:36:06,470 --> 00:36:10,300
directly from us . Uh , provides I 

809
00:36:10,310 --> 00:36:12,690
think you know the American people with 

810
00:36:12,700 --> 00:36:15,420
confidence . Number one , number two , 

811
00:36:15,430 --> 00:36:18,370
Health and Human Services , uh , is 

812
00:36:18,380 --> 00:36:21,650
working a roll out of a communication 

813
00:36:21,650 --> 00:36:24,210
strategy ? Uh , that will talk about 

814
00:36:24,220 --> 00:36:27,580
overall confidence of vaccines . Never 

815
00:36:27,580 --> 00:36:30,460
mind Cove it , but total vaccine 

816
00:36:30,470 --> 00:36:33,140
confidence they will narrow it down to 

817
00:36:33,140 --> 00:36:36,930
the co vid vaccine itself on . Then 

818
00:36:36,940 --> 00:36:40,330
they're going thio start to establish 

819
00:36:40,340 --> 00:36:43,680
communication at the national state and 

820
00:36:43,680 --> 00:36:46,120
local community level on , you know , 

821
00:36:46,120 --> 00:36:47,842
when vaccines were going to be 

822
00:36:47,842 --> 00:36:51,200
available to all persons inappropriate 

823
00:36:51,200 --> 00:36:54,780
time accordingly . A said initially , 

824
00:36:54,790 --> 00:36:57,800
uh , you know , to , uh , probably 

825
00:36:57,810 --> 00:37:00,032
healthcare workers frontline healthcare 

826
00:37:00,032 --> 00:37:02,800
workers and then , uh , the elderly , 

827
00:37:02,810 --> 00:37:05,960
long term , clearly been advertised and 

828
00:37:05,960 --> 00:37:08,530
talked about quite a bit . But then 

829
00:37:08,530 --> 00:37:10,980
what happens ? Beyond that is where we 

830
00:37:10,980 --> 00:37:13,036
want to get the messaging out to all 

831
00:37:13,036 --> 00:37:16,960
Americans . So thank you . Next 

832
00:37:16,960 --> 00:37:20,290
question . Our next question is from 

833
00:37:20,290 --> 00:37:22,950
Candice Choi with AP the Associated 

834
00:37:22,950 --> 00:37:26,330
Press Your line is open . Hi . Thanks . 

835
00:37:26,340 --> 00:37:29,490
How closely will you be urging states 

836
00:37:29,500 --> 00:37:32,330
to follow a priority recommendations ? 

837
00:37:32,340 --> 00:37:34,396
And do you have any indications that 

838
00:37:34,396 --> 00:37:36,340
they distributions might vary from 

839
00:37:36,340 --> 00:37:38,396
those recommendations and if they're 

840
00:37:38,396 --> 00:37:40,396
going to be any federal guidance on 

841
00:37:40,396 --> 00:37:42,730
whether people who've been infected 

842
00:37:42,730 --> 00:37:44,119
should get the vaccine ? 

843
00:37:45,980 --> 00:37:49,160
So in regard of your second question , 

844
00:37:50,130 --> 00:37:53,450
here are the facts In the trials , 

845
00:37:53,930 --> 00:37:56,270
people were recruited on the basis off 

846
00:37:56,270 --> 00:37:59,270
not having had overt clinical , covet 

847
00:37:59,270 --> 00:38:01,340
disease or symptoms , etcetera . 

848
00:38:03,120 --> 00:38:05,231
On that basis , they were recruited . 

849
00:38:05,231 --> 00:38:07,287
It turns out , anywhere between five 

850
00:38:07,287 --> 00:38:10,560
and 10% of the subjects recruited we're 

851
00:38:10,560 --> 00:38:14,440
syrah , positive to covet 19 . In 

852
00:38:14,440 --> 00:38:16,384
other words , they most likely had 

853
00:38:16,384 --> 00:38:18,607
asymptomatic or very mildly symptomatic 

854
00:38:18,607 --> 00:38:21,480
disease and didn't notice it . So what 

855
00:38:21,480 --> 00:38:24,580
we know is that the vaccines are safe 

856
00:38:24,590 --> 00:38:27,280
in these populations and quite 

857
00:38:27,280 --> 00:38:29,530
significant numbers off Syria . 

858
00:38:29,530 --> 00:38:32,190
Positives have been immunized and their 

859
00:38:32,190 --> 00:38:34,350
immune responses are being analyzed . 

860
00:38:34,350 --> 00:38:36,517
My expectation is that they would have 

861
00:38:36,517 --> 00:38:38,572
very , very high immune responses in 

862
00:38:38,572 --> 00:38:40,628
response to the vaccine because they 

863
00:38:40,628 --> 00:38:42,461
were already private through the 

864
00:38:42,461 --> 00:38:44,770
infection . Where we do not have data 

865
00:38:44,780 --> 00:38:47,910
is in subjects in videos who have had 

866
00:38:47,920 --> 00:38:50,880
over to disease . That's an important 

867
00:38:50,880 --> 00:38:53,920
question that we will need thio address 

868
00:38:53,930 --> 00:38:56,860
through clinical studies . Now what we 

869
00:38:56,860 --> 00:38:58,971
also know from the literature is that 

870
00:38:58,971 --> 00:39:01,830
people who get overt disease in general 

871
00:39:02,170 --> 00:39:04,270
have higher immune response to the 

872
00:39:04,270 --> 00:39:06,381
virus and people who have subclinical 

873
00:39:06,920 --> 00:39:09,870
disease . So the expectations is for 

874
00:39:09,870 --> 00:39:13,250
them to be more protected , but that 

875
00:39:13,260 --> 00:39:16,460
studies will need to be done . What we 

876
00:39:16,460 --> 00:39:18,970
do know , uh , to the first part of the 

877
00:39:18,970 --> 00:39:21,300
question is , Is that the staffs that 

878
00:39:21,300 --> 00:39:23,356
each of the jurisdictions are highly 

879
00:39:23,356 --> 00:39:26,060
professionals , medically trained and 

880
00:39:26,060 --> 00:39:28,870
have a clear understanding of the role 

881
00:39:28,870 --> 00:39:32,220
of the FDA and the U . A and the C D . 

882
00:39:32,220 --> 00:39:35,900
C slash a sip on . We are 100% 

883
00:39:35,910 --> 00:39:38,480
confident in , based on our 

884
00:39:38,490 --> 00:39:41,280
deliberation and coordination with them , 

885
00:39:41,290 --> 00:39:44,860
that they understand how to implement 

886
00:39:44,870 --> 00:39:47,450
their plan in accordance to that , And 

887
00:39:47,450 --> 00:39:50,090
I don't have any indicator that says 

888
00:39:50,090 --> 00:39:52,312
they would go outside of those things . 

889
00:39:53,920 --> 00:39:57,720
Next question . Our next question is 

890
00:39:57,720 --> 00:40:00,870
from Angelica La Vita with Bloomberg 

891
00:40:00,870 --> 00:40:04,090
News . Your line is open . Thank you . 

892
00:40:04,100 --> 00:40:06,070
Well , all of the initial doses be 

893
00:40:06,070 --> 00:40:08,680
available , um , to the states at first . 

894
00:40:08,690 --> 00:40:10,912
Or will the federal government allocate 

895
00:40:10,912 --> 00:40:13,100
any of those doses directly ? And if 

896
00:40:13,100 --> 00:40:15,044
it's the latter , who will they be 

897
00:40:15,044 --> 00:40:17,440
given to and what priority order ? So 

898
00:40:17,440 --> 00:40:19,810
right now , the allocations or for the 

899
00:40:19,810 --> 00:40:23,440
64 jurisdictions on five federal 

900
00:40:23,440 --> 00:40:26,410
agencies . Um , but that's they're all 

901
00:40:26,410 --> 00:40:28,770
gonna go out . Simultaneous , fair and 

902
00:40:28,780 --> 00:40:30,502
equitable to the amount that's 

903
00:40:30,502 --> 00:40:33,830
available . It's pro rata to population . 

904
00:40:33,840 --> 00:40:37,290
It is . It is a insisted on it . It's a 

905
00:40:37,290 --> 00:40:40,830
math problem and execution so that we 

906
00:40:40,830 --> 00:40:42,830
can ensure fair and equitable 

907
00:40:42,830 --> 00:40:46,230
distribution . Next question . 

908
00:40:48,310 --> 00:40:50,630
Our next question is from Tom . How you 

909
00:40:50,640 --> 00:40:52,751
with Washington Press ? You're like , 

910
00:40:52,751 --> 00:40:54,973
Oh , I'm sorry . Washington Post , Your 

911
00:40:54,973 --> 00:40:57,430
line is open . Hey , it's , uh , Tom . 

912
00:40:57,430 --> 00:40:59,597
How from the Washington Times . Thanks 

913
00:40:59,597 --> 00:41:01,597
for doing the call . Just wanted to 

914
00:41:01,597 --> 00:41:03,486
know what you're hearing from the 

915
00:41:03,486 --> 00:41:05,486
States in terms of their ability to 

916
00:41:05,486 --> 00:41:07,597
distribute the vaccine . Uh , do they 

917
00:41:07,597 --> 00:41:09,708
have enough funding ? Thio . It's one 

918
00:41:09,708 --> 00:41:11,874
thing to ship it to him to have enough 

919
00:41:11,874 --> 00:41:13,986
funding to distribute it for Congress 

920
00:41:13,986 --> 00:41:17,930
to step in and provide more . So a lot 

921
00:41:17,930 --> 00:41:20,041
of work is going in the collaboration 

922
00:41:20,041 --> 00:41:23,690
and coordination of the distribution to 

923
00:41:23,700 --> 00:41:25,811
what we would like to see down to the 

924
00:41:25,811 --> 00:41:28,940
lowest level . And so a zloty as , uh , 

925
00:41:28,950 --> 00:41:31,680
they have the provider enrolled , right ? 

926
00:41:31,690 --> 00:41:35,510
E doctor's office or hospital CVS , 

927
00:41:35,510 --> 00:41:38,300
Walgreens , etcetera . 

928
00:41:38,310 --> 00:41:40,920
Uh , then the vaccine could be 

929
00:41:40,920 --> 00:41:43,780
delivered to those locations . Um , and 

930
00:41:43,780 --> 00:41:45,880
in theory , administered at those 

931
00:41:45,880 --> 00:41:48,690
locations . If the state chooses that , 

932
00:41:48,690 --> 00:41:51,830
they would rather have it go to certain 

933
00:41:51,840 --> 00:41:54,270
on DWI will deliver to those locations . 

934
00:41:54,280 --> 00:41:56,447
If the state chooses , they'd like toe 

935
00:41:56,447 --> 00:41:59,210
execute a hub and spoke to ensure that 

936
00:41:59,210 --> 00:42:02,860
they are executing their plan . Uh , we 

937
00:42:02,860 --> 00:42:04,804
will deliver to the hubs that they 

938
00:42:04,804 --> 00:42:07,470
designate , Uh , and if they require 

939
00:42:07,480 --> 00:42:11,090
additional assets and , um , support 

940
00:42:11,090 --> 00:42:14,140
from there , we've been talking to him 

941
00:42:14,140 --> 00:42:16,760
about making sure they have a detailed 

942
00:42:16,760 --> 00:42:19,840
plan , uh , with specificity and what 

943
00:42:19,840 --> 00:42:22,062
the requirement would be and then tow . 

944
00:42:22,062 --> 00:42:24,820
Let us know so that we can help help 

945
00:42:24,820 --> 00:42:26,820
enable them with that . They have 

946
00:42:26,820 --> 00:42:29,370
received funding , uh , in this light 

947
00:42:29,380 --> 00:42:31,780
previously , which with additional 

948
00:42:31,780 --> 00:42:34,410
funding , up to 200 million , with an 

949
00:42:34,410 --> 00:42:36,150
additional 140 million being 

950
00:42:36,150 --> 00:42:38,420
distributed out to the jurisdictions , 

951
00:42:38,430 --> 00:42:41,380
uh , this month to support them in that 

952
00:42:41,380 --> 00:42:45,240
execution . Next question . 

953
00:42:46,600 --> 00:42:48,630
Our next question is from Rebecca 

954
00:42:48,630 --> 00:42:50,741
Robbins . If you want to mind stating 

955
00:42:50,741 --> 00:42:52,963
your organization , your line is open . 

956
00:42:54,200 --> 00:42:56,200
Hello ? Yes , this is Rebecca Robin 

957
00:42:56,200 --> 00:42:58,422
from The New York Times . Thank you for 

958
00:42:58,422 --> 00:43:00,256
taking my question . My question 

959
00:43:00,256 --> 00:43:02,144
pertains Thio , the vaccine being 

960
00:43:02,144 --> 00:43:04,310
developed by AstraZeneca and the 

961
00:43:04,310 --> 00:43:06,650
University of Oxford . And I'm curious 

962
00:43:06,650 --> 00:43:08,680
if you could tell me what the 

963
00:43:08,680 --> 00:43:11,560
expectation is in terms of the data 

964
00:43:11,560 --> 00:43:14,390
that will be necessary for the FDA to 

965
00:43:14,390 --> 00:43:16,280
consider of an emergency use 

966
00:43:16,280 --> 00:43:18,470
authorization . Uh , do you anticipate 

967
00:43:18,470 --> 00:43:20,770
that they will need to submit data from 

968
00:43:20,780 --> 00:43:23,150
the phase three trial in the United 

969
00:43:23,160 --> 00:43:26,990
States ? Uh , and was that the plan , 

970
00:43:27,000 --> 00:43:29,056
and if so , how long has that defend 

971
00:43:29,056 --> 00:43:31,490
the plan ? Thank you . So first , I 

972
00:43:31,490 --> 00:43:34,460
should say that the FDA defines what 

973
00:43:34,460 --> 00:43:38,040
the FDA would like to see into the 

974
00:43:38,040 --> 00:43:41,930
file on . It's not the operation 

975
00:43:41,930 --> 00:43:43,930
that does that or the company . But 

976
00:43:44,000 --> 00:43:46,880
having said that , I do think that 

977
00:43:46,880 --> 00:43:50,610
there is a large set of data 

978
00:43:51,190 --> 00:43:53,301
coming out of the UK and Brazil trial 

979
00:43:53,301 --> 00:43:55,900
in terms of ethics and safety . That 

980
00:43:55,900 --> 00:43:58,560
data is still being digested because 

981
00:43:58,560 --> 00:44:00,910
off the contrasted outcome that 

982
00:44:00,910 --> 00:44:04,100
happened in regard off the immunization 

983
00:44:04,690 --> 00:44:07,420
regiment that was used . And it's not 

984
00:44:07,990 --> 00:44:10,750
obvious or straightforward to come to a 

985
00:44:10,750 --> 00:44:13,070
conclusion why there appears to have 

986
00:44:13,080 --> 00:44:15,610
bean substantially different efficacy 

987
00:44:15,610 --> 00:44:18,710
outcomes 90% to 62% . 

988
00:44:19,290 --> 00:44:22,150
Andi . Frankly , unless there is a very 

989
00:44:22,150 --> 00:44:25,110
clear explanation based on facts and 

990
00:44:25,110 --> 00:44:27,700
data off , what's behind those two 

991
00:44:27,700 --> 00:44:30,690
numbers ? It's very likely that that 

992
00:44:30,700 --> 00:44:33,510
package will not be sufficient for , um , 

993
00:44:33,510 --> 00:44:35,732
approval . I'll be the first one to say 

994
00:44:35,732 --> 00:44:37,843
so I say here . But of course the FDA 

995
00:44:37,843 --> 00:44:40,130
will make their own decision next to 

996
00:44:40,130 --> 00:44:43,000
that clinical set of data and safety 

997
00:44:43,000 --> 00:44:45,090
data , which is quite important and 

998
00:44:45,090 --> 00:44:48,000
significant in the numbers is , of 

999
00:44:48,000 --> 00:44:50,167
course , also the manufacturing data . 

1000
00:44:50,400 --> 00:44:52,740
The FDA will want to understand the 

1001
00:44:52,740 --> 00:44:54,407
manufacturing process and the 

1002
00:44:54,407 --> 00:44:56,573
facilities in which the clinical trial 

1003
00:44:56,573 --> 00:44:59,230
material used in the trials has bean 

1004
00:45:00,190 --> 00:45:02,490
produce and those facilities air in the 

1005
00:45:02,490 --> 00:45:06,070
UK and in Italy for the clinical trials 

1006
00:45:06,070 --> 00:45:08,990
conducted in the UK in Brazil and also 

1007
00:45:08,990 --> 00:45:11,101
for the clinical trial conducted here 

1008
00:45:11,290 --> 00:45:13,770
in the U . S . On top of that , the FDA , 

1009
00:45:13,770 --> 00:45:17,240
we want to understand and characterized 

1010
00:45:17,240 --> 00:45:19,351
the manufacturing process that's been 

1011
00:45:19,351 --> 00:45:22,700
using here in the US at emergent by 

1012
00:45:22,710 --> 00:45:25,760
science is that by solution story that 

1013
00:45:25,760 --> 00:45:29,440
is used to produce what we call the 

1014
00:45:29,440 --> 00:45:32,690
commercial vaccine and we will need to 

1015
00:45:32,690 --> 00:45:34,523
demonstrate that that vaccine is 

1016
00:45:34,523 --> 00:45:36,840
identical technically to the vaccine 

1017
00:45:36,840 --> 00:45:40,140
used into the clinical trial . My hunch 

1018
00:45:40,150 --> 00:45:43,020
is that by the time we generate 

1019
00:45:43,670 --> 00:45:46,390
AstraZeneca , Oxford University , all 

1020
00:45:46,390 --> 00:45:48,840
this set of data , the data from the 

1021
00:45:48,840 --> 00:45:51,410
ongoing FXC trial phase three in the U . 

1022
00:45:51,410 --> 00:45:53,740
S . With the AstraZeneca vaccine will 

1023
00:45:53,740 --> 00:45:57,190
come out . That's a fully self 

1024
00:45:57,190 --> 00:45:59,468
sufficient trial . There is no pooling . 

1025
00:45:59,468 --> 00:46:01,690
There is no geographic diversity within 

1026
00:46:01,690 --> 00:46:05,110
it . I think it's trial that we and the 

1027
00:46:05,110 --> 00:46:07,700
FDA have overseen totally . 

1028
00:46:09,420 --> 00:46:12,210
Ultimately , it may have the largest 

1029
00:46:12,210 --> 00:46:15,780
weight in the in the decision around 

1030
00:46:15,780 --> 00:46:18,550
that I don't think it changes a lot . 

1031
00:46:18,650 --> 00:46:21,310
The timelines . I still would expect 

1032
00:46:21,320 --> 00:46:25,090
that somewhere in January , maybe 

1033
00:46:25,380 --> 00:46:27,720
more towards the second half of January , 

1034
00:46:28,130 --> 00:46:30,080
data will become available on 

1035
00:46:30,090 --> 00:46:31,701
potentially an emergency use 

1036
00:46:31,701 --> 00:46:33,940
authorization could be filed . Thank 

1037
00:46:33,940 --> 00:46:35,700
you . Next question . 

1038
00:46:37,980 --> 00:46:40,490
Our next question is from Sarah Murray 

1039
00:46:40,490 --> 00:46:44,380
with CNN . Your line is open . Hi . 

1040
00:46:44,390 --> 00:46:46,334
Thank you all for doing the call . 

1041
00:46:46,334 --> 00:46:48,760
Appreciate it . Um , first , I just 

1042
00:46:48,760 --> 00:46:50,927
wanted to see if you could tell us the 

1043
00:46:50,927 --> 00:46:53,500
five federal emergencies that will be 

1044
00:46:53,510 --> 00:46:56,770
getting the vaccine allotment . And 

1045
00:46:56,780 --> 00:46:59,750
secondly , just to clarify the data 

1046
00:46:59,760 --> 00:47:03,000
systems will each day be responsible 

1047
00:47:03,000 --> 00:47:06,930
for tracking the first shots and 

1048
00:47:06,940 --> 00:47:08,996
their residents and then making sure 

1049
00:47:08,996 --> 00:47:11,107
they come in for the second shot . Is 

1050
00:47:11,107 --> 00:47:13,273
there any sort of federal role in that 

1051
00:47:13,273 --> 00:47:15,384
system , or is it all of the States ? 

1052
00:47:15,680 --> 00:47:18,950
So the five federal agencies are the 

1053
00:47:18,960 --> 00:47:21,280
veterans affair Department of Defense , 

1054
00:47:21,290 --> 00:47:23,330
Department of State , Indian Health 

1055
00:47:23,330 --> 00:47:26,090
Services and Bureau . Federal prisons . 

1056
00:47:26,580 --> 00:47:29,640
Uh , the second question about tracking , 

1057
00:47:29,650 --> 00:47:33,230
um , second dose is what we've done is 

1058
00:47:33,240 --> 00:47:35,650
we've set up everything from , uh , 

1059
00:47:35,660 --> 00:47:38,970
draconian process where when we sent 

1060
00:47:38,970 --> 00:47:41,960
out the ancillary kits which which have 

1061
00:47:41,960 --> 00:47:44,630
needles and syringes , we've included 

1062
00:47:44,640 --> 00:47:48,640
paper cards to be filled out and sent 

1063
00:47:48,650 --> 00:47:50,261
to , you know , given to the 

1064
00:47:50,261 --> 00:47:53,620
individuals reminding them off their of 

1065
00:47:53,620 --> 00:47:56,230
their next vaccine . Do they 

1066
00:47:56,240 --> 00:47:58,490
accordingly encouragement of taking a 

1067
00:47:58,490 --> 00:48:00,768
photo of it , putting it in the wallet , 

1068
00:48:00,768 --> 00:48:02,790
etcetera . Um , you know , we're 

1069
00:48:02,790 --> 00:48:04,957
working at the draconian level . Their 

1070
00:48:04,957 --> 00:48:08,170
second states are working plans for 

1071
00:48:08,170 --> 00:48:11,070
notification . Uh , notification and 

1072
00:48:11,070 --> 00:48:13,700
information inside of state laws is 

1073
00:48:13,700 --> 00:48:15,830
very particular in some states , um , 

1074
00:48:15,840 --> 00:48:19,180
very open , and others on each state is 

1075
00:48:19,180 --> 00:48:22,820
working that plan inside of their 

1076
00:48:22,820 --> 00:48:25,840
own . Um , within all the rules and 

1077
00:48:25,850 --> 00:48:29,690
regulations on laws , we do know 

1078
00:48:29,690 --> 00:48:33,090
that , uh , pharmacies such as CVS and 

1079
00:48:33,090 --> 00:48:35,380
Walgreens have established very 

1080
00:48:35,380 --> 00:48:37,760
elaborate tracking systems . Right ? 

1081
00:48:37,770 --> 00:48:40,800
Thio set up appointments , notify 

1082
00:48:40,800 --> 00:48:44,260
people when they're second shots are 

1083
00:48:44,270 --> 00:48:46,810
required , etcetera , at the federal 

1084
00:48:46,810 --> 00:48:49,200
level . What ? We're working and we 

1085
00:48:49,200 --> 00:48:51,830
have capability and capacity . Um , 

1086
00:48:51,840 --> 00:48:55,800
thio send second , uh , those 

1087
00:48:55,800 --> 00:48:59,170
messages out on Lee if and when it's in 

1088
00:48:59,170 --> 00:49:01,920
collaboration with states , laws and 

1089
00:49:01,920 --> 00:49:04,630
regulations and policies . Uh , eso 

1090
00:49:04,640 --> 00:49:07,600
triple canopy approach to trying to 

1091
00:49:07,600 --> 00:49:10,210
make this work on die . We're doing our 

1092
00:49:10,210 --> 00:49:13,110
best to capture everybody to ensure 

1093
00:49:13,110 --> 00:49:15,610
that they get their second dose . Thank 

1094
00:49:15,610 --> 00:49:17,090
you . Next question . 

1095
00:49:19,470 --> 00:49:22,140
Our next question is from Emily Count . 

1096
00:49:22,150 --> 00:49:24,780
If you would mind announcing your 

1097
00:49:24,780 --> 00:49:28,610
organization , your line is open . Hi , 

1098
00:49:28,610 --> 00:49:31,170
this is Emily Cop with CQ roll call . I 

1099
00:49:31,170 --> 00:49:33,620
was hoping you could clarify how you 

1100
00:49:33,620 --> 00:49:36,520
drew the chalk line of December 15th . 

1101
00:49:36,530 --> 00:49:38,752
Was that through conversations with the 

1102
00:49:38,752 --> 00:49:41,470
FDA And is there any pressure on the 

1103
00:49:41,470 --> 00:49:44,370
FDA ? Teoh , make a decision by that 

1104
00:49:44,380 --> 00:49:47,800
date . Given that Be that you're , um 

1105
00:49:48,170 --> 00:49:51,600
I'm planning on Thanks . Okay . So , uh , 

1106
00:49:51,610 --> 00:49:53,610
you know , I'm an army general . An 

1107
00:49:53,610 --> 00:49:57,010
Army generals plan . And so literally I 

1108
00:49:57,010 --> 00:49:59,520
got up on my white board , right ? And 

1109
00:49:59,520 --> 00:50:02,850
I said , Oh , they filed for you , eh ? 

1110
00:50:02,860 --> 00:50:06,190
On this day . And then I got word that 

1111
00:50:06,190 --> 00:50:08,520
said , the verb pack sessions we're 

1112
00:50:08,520 --> 00:50:11,750
gonna be on this day . So they filed 

1113
00:50:11,760 --> 00:50:15,540
ver pack was specified on . Then I 

1114
00:50:15,540 --> 00:50:18,620
said , OK , somewhere in this window 

1115
00:50:18,630 --> 00:50:20,630
right after they walked through the 

1116
00:50:20,630 --> 00:50:23,530
details is probably the earliest 

1117
00:50:23,530 --> 00:50:27,210
potential opportunity for you . A . My 

1118
00:50:27,210 --> 00:50:31,060
white board clearly speculates , only 

1119
00:50:31,070 --> 00:50:34,930
if the EU a approve would distribution 

1120
00:50:34,940 --> 00:50:38,350
begin . But we needed to dio an 

1121
00:50:38,360 --> 00:50:40,610
estimated date so we could backwards 

1122
00:50:40,610 --> 00:50:43,720
plan the requirements for distribution . 

1123
00:50:43,730 --> 00:50:45,970
For example , if we think it's coming 

1124
00:50:45,970 --> 00:50:48,260
out on that day and we wanted 

1125
00:50:48,260 --> 00:50:50,020
distribute available vaccines 

1126
00:50:50,020 --> 00:50:52,290
immediately following several 

1127
00:50:52,290 --> 00:50:54,401
administrative things have to occur . 

1128
00:50:54,560 --> 00:50:57,510
One . The states need to tell us where 

1129
00:50:57,510 --> 00:50:59,621
they would like the vaccine delivered 

1130
00:50:59,621 --> 00:51:02,260
to at what quantities to the companies 

1131
00:51:02,260 --> 00:51:05,260
have to prepare the packages . Um and 

1132
00:51:05,260 --> 00:51:08,660
so all 64 jurisdictions , times x 

1133
00:51:08,670 --> 00:51:11,370
number of locations , times x number of 

1134
00:51:11,370 --> 00:51:14,050
doses has to be prepared and put into 

1135
00:51:14,050 --> 00:51:16,600
storage . Three . The coordination 

1136
00:51:16,600 --> 00:51:20,150
between the major trucking distribution , 

1137
00:51:20,150 --> 00:51:23,070
McKesson and the primes that are going 

1138
00:51:23,070 --> 00:51:26,080
to support it . FedEx and ups have to 

1139
00:51:26,080 --> 00:51:28,920
be brought into the plan for execution . 

1140
00:51:28,930 --> 00:51:32,390
And then four , of course . Um , it is , 

1141
00:51:32,400 --> 00:51:34,344
you know , the notification to the 

1142
00:51:34,344 --> 00:51:36,344
administration sites that they will 

1143
00:51:36,344 --> 00:51:38,690
receive vaccine accordingly . So , in 

1144
00:51:38,690 --> 00:51:41,780
simple terms , it is a white board plan . 

1145
00:51:41,790 --> 00:51:45,000
Uh , it is meant to help us prepare , 

1146
00:51:45,360 --> 00:51:47,780
but it is not constraining toe 

1147
00:51:47,790 --> 00:51:51,720
execution . And there is 100% 

1148
00:51:51,730 --> 00:51:55,080
without question , no interference with 

1149
00:51:55,080 --> 00:51:58,560
the FDA . And they're very deliberate , 

1150
00:51:58,570 --> 00:52:02,550
arduous effort to make sure 

1151
00:52:02,550 --> 00:52:05,160
that we have , uh , the right solution 

1152
00:52:05,170 --> 00:52:07,440
if they if and when they do approve EU 

1153
00:52:07,440 --> 00:52:11,070
a You next question . 

1154
00:52:12,550 --> 00:52:14,439
Our next question is from Caitlin 

1155
00:52:14,439 --> 00:52:16,494
Kenney with Stars and Stripes . Your 

1156
00:52:16,494 --> 00:52:20,170
line is open . Hi . Thank you . Killing 

1157
00:52:20,170 --> 00:52:22,170
Kenny with stars and Stripes . Um , 

1158
00:52:22,170 --> 00:52:24,337
since the D . O . D . Is getting their 

1159
00:52:24,337 --> 00:52:26,503
own allocation , can you talk a little 

1160
00:52:26,503 --> 00:52:28,670
bit about what their distribution plan 

1161
00:52:28,670 --> 00:52:30,837
is among the force ? Um , do they have 

1162
00:52:30,837 --> 00:52:32,781
their own priority of who gets the 

1163
00:52:32,781 --> 00:52:35,003
vaccine first ? Or are they following , 

1164
00:52:35,003 --> 00:52:34,600
like , the phase one A for their health 

1165
00:52:34,600 --> 00:52:36,910
care workers and then phase one B for 

1166
00:52:36,910 --> 00:52:39,680
who they believe are essential workers . 

1167
00:52:39,680 --> 00:52:42,210
Thanks . So , just like we're doing for 

1168
00:52:42,220 --> 00:52:44,640
the jurisdictions , the federal 

1169
00:52:44,640 --> 00:52:47,190
agencies have their own plans were 

1170
00:52:47,190 --> 00:52:49,430
supporting them with fair and equitable 

1171
00:52:49,440 --> 00:52:53,160
allocation based on population of 

1172
00:52:53,160 --> 00:52:56,640
their force . Uh , and so they will 

1173
00:52:56,650 --> 00:52:58,928
figure out their plan . They're , well , 

1174
00:52:58,928 --> 00:53:01,094
understanding . And they have the same 

1175
00:53:01,094 --> 00:53:03,950
professionals that the jurisdictions 

1176
00:53:03,950 --> 00:53:06,840
have , um , in their alignment and 

1177
00:53:06,850 --> 00:53:10,060
execution of the FDA and you a guidance 

1178
00:53:10,150 --> 00:53:12,990
as well as the 500 a sip guidance . 

1179
00:53:13,350 --> 00:53:16,560
I do not know what the 

1180
00:53:16,950 --> 00:53:19,220
Department of Defense's plan is after 

1181
00:53:19,220 --> 00:53:22,140
that . I think we have time for two 

1182
00:53:22,140 --> 00:53:24,307
more questions on today's briefing and 

1183
00:53:24,307 --> 00:53:26,529
again , follow up Questions can be sent 

1184
00:53:26,529 --> 00:53:28,584
to media at HHS dot gov . We'll take 

1185
00:53:28,584 --> 00:53:30,770
two more questions . Our next question 

1186
00:53:30,770 --> 00:53:33,780
is , from whom are fun with box . Your 

1187
00:53:33,780 --> 00:53:37,690
line is open . Hi , this is a marathon 

1188
00:53:37,690 --> 00:53:40,210
of a reporter at box for Dr Slowly . 

1189
00:53:40,210 --> 00:53:42,099
You talked a little bit about the 

1190
00:53:42,099 --> 00:53:44,321
Johnson Johnson Jansen vaccine . That's 

1191
00:53:44,321 --> 00:53:46,321
a one dose vaccine . How would that 

1192
00:53:46,321 --> 00:53:48,543
coming to fruition affect the plans for 

1193
00:53:48,543 --> 00:53:50,543
distribution ? Would operation warp 

1194
00:53:50,543 --> 00:53:52,766
speed you know , shit , That's resource 

1195
00:53:52,766 --> 00:53:54,988
is toward the one resource vaccine , Or 

1196
00:53:54,988 --> 00:53:57,043
how would that allocation proceed at 

1197
00:53:57,043 --> 00:53:59,490
that point ? Well , I mean first , of 

1198
00:53:59,490 --> 00:54:01,650
course , we need to look into the 

1199
00:54:01,660 --> 00:54:03,760
performance . I should I should say 

1200
00:54:03,760 --> 00:54:07,560
that strategically , we decided with 

1201
00:54:07,560 --> 00:54:10,360
that vaccine to try one shot vaccine . 

1202
00:54:10,940 --> 00:54:13,107
But at the same time , we also decided 

1203
00:54:13,107 --> 00:54:15,329
to test it as a two shots vaccine . And 

1204
00:54:15,329 --> 00:54:19,020
that face retrial has started . Or this 

1205
00:54:19,020 --> 00:54:22,030
will cover all bases . If you wish . In 

1206
00:54:22,030 --> 00:54:24,141
terms of distribution , General Purna 

1207
00:54:24,141 --> 00:54:26,308
can command further , but there should 

1208
00:54:26,308 --> 00:54:28,530
be no difference . It z literally enter 

1209
00:54:28,530 --> 00:54:30,697
into the cadence off distributing that 

1210
00:54:30,697 --> 00:54:33,330
those except there would be no recall 

1211
00:54:33,700 --> 00:54:35,922
to the to the subject that received the 

1212
00:54:35,922 --> 00:54:39,000
first does toe come back . It's gonna 

1213
00:54:39,000 --> 00:54:41,460
be effectively , amore efficient , 

1214
00:54:42,040 --> 00:54:44,680
faster strategy to immunize , which is 

1215
00:54:44,680 --> 00:54:47,150
particularly important in when there is 

1216
00:54:47,150 --> 00:54:49,372
a very active pandemic . And that's the 

1217
00:54:49,372 --> 00:54:51,200
reason we wanted to assess the 

1218
00:54:51,210 --> 00:54:54,340
potential . Thank you . I'm sorry . It 

1219
00:54:54,340 --> 00:54:56,760
would be additive to the amounts that 

1220
00:54:56,760 --> 00:54:58,760
we're sending out from Moderna and 

1221
00:54:58,760 --> 00:55:01,980
Pfizer on . Then we would do our 

1222
00:55:01,980 --> 00:55:04,760
initial push based on you and what's 

1223
00:55:04,760 --> 00:55:07,510
available on . Then we would put them 

1224
00:55:07,520 --> 00:55:10,160
in the cadence as Dr Salah we indicated , 

1225
00:55:10,440 --> 00:55:13,480
um , in normal routine distribution 

1226
00:55:13,840 --> 00:55:16,020
accordingly . So the states and 

1227
00:55:16,020 --> 00:55:18,260
jurisdictions would then have three 

1228
00:55:18,260 --> 00:55:21,770
vaccines , um , Thio to distribute to 

1229
00:55:21,770 --> 00:55:24,550
their plan . Final question , please . 

1230
00:55:27,020 --> 00:55:29,187
The last question is from . And you're 

1231
00:55:29,187 --> 00:55:30,742
done with business inside . 

1232
00:55:42,740 --> 00:55:46,500
And Andrew didn't get Go ahead , sir . 

1233
00:55:55,740 --> 00:55:57,851
We can't hear . Can't hear anything . 

1234
00:55:58,050 --> 00:55:59,850
Somebody , somebody commute 

1235
00:56:05,130 --> 00:56:07,352
operator will go to the next question . 

1236
00:56:07,830 --> 00:56:09,608
Sure , not a problem . Our next 

1237
00:56:09,608 --> 00:56:11,774
question is from Hassam . Ahmed , with 

1238
00:56:11,774 --> 00:56:15,650
SP Your line is open . Uh , hi . Thank 

1239
00:56:15,650 --> 00:56:18,500
you for taking my question and doing 

1240
00:56:18,500 --> 00:56:20,833
this interaction . Um , can you hear me ? 

1241
00:56:21,020 --> 00:56:24,790
Yes . Yeah . Eso I 

1242
00:56:24,790 --> 00:56:27,510
had a question for Dr Lori if you've 

1243
00:56:27,510 --> 00:56:30,110
been following at all . Um , the 

1244
00:56:30,120 --> 00:56:32,350
Russian data from , uh , with regards 

1245
00:56:32,360 --> 00:56:34,582
to the spot make vaccine , which I know 

1246
00:56:34,582 --> 00:56:36,804
they haven't accrued that much , but it 

1247
00:56:36,804 --> 00:56:38,916
looks relatively promising . I wonder 

1248
00:56:38,916 --> 00:56:41,138
if you have any thoughts regarding that 

1249
00:56:41,138 --> 00:56:41,010
and whether that could ever be a 

1250
00:56:41,010 --> 00:56:43,170
possibility for the U . S . 

1251
00:56:44,130 --> 00:56:46,950
Onda . Second part of the question was , 

1252
00:56:46,960 --> 00:56:49,630
um do you expect all three million 

1253
00:56:49,630 --> 00:56:51,797
nursing home residents and most health 

1254
00:56:51,797 --> 00:56:53,852
care workers to be vaccinated by the 

1255
00:56:53,852 --> 00:56:56,680
end of this year ? So , regarding the 

1256
00:56:56,680 --> 00:56:59,580
first question , frankly , very scars 

1257
00:56:59,590 --> 00:57:01,701
access to any data . Only whatever is 

1258
00:57:01,701 --> 00:57:04,080
in the public domain . The one thing I 

1259
00:57:04,080 --> 00:57:06,800
would comment on is that the vector 

1260
00:57:06,800 --> 00:57:09,560
used , which is a virus similar than 

1261
00:57:09,560 --> 00:57:13,260
Virus five has bean , associate ID in 

1262
00:57:13,260 --> 00:57:16,880
HIV clinical trials with an increased 

1263
00:57:17,010 --> 00:57:20,980
susceptibility to acquiring HIV in 

1264
00:57:20,990 --> 00:57:23,480
subjects that were immunized with an 

1265
00:57:23,480 --> 00:57:26,560
HIV vaccine using that vector . So a 

1266
00:57:26,560 --> 00:57:29,660
word of caution as to exactly what kind 

1267
00:57:29,660 --> 00:57:31,827
of molecular engineering may have bean 

1268
00:57:31,827 --> 00:57:35,670
done on their vector to avoid what 

1269
00:57:35,680 --> 00:57:38,890
should obviously be avoided , which has 

1270
00:57:38,890 --> 00:57:40,946
increased its activities . According 

1271
00:57:41,110 --> 00:57:44,030
HIV , I believe it was in the male 

1272
00:57:44,030 --> 00:57:47,730
population , a za regard to the 

1273
00:57:47,730 --> 00:57:50,190
vaccination off the long term care 

1274
00:57:50,190 --> 00:57:53,220
facility residents , elderly , frail 

1275
00:57:53,230 --> 00:57:55,430
people . It's really gonna be a 

1276
00:57:55,430 --> 00:57:57,440
decision that will be based on the 

1277
00:57:57,440 --> 00:57:59,820
recommendation from the CDC and its 

1278
00:57:59,820 --> 00:58:01,764
advisory committee on immunization 

1279
00:58:01,764 --> 00:58:05,060
practices , as well as the 

1280
00:58:05,430 --> 00:58:08,230
adherence or variance from that 

1281
00:58:08,230 --> 00:58:11,790
recommendation by the each state health 

1282
00:58:11,800 --> 00:58:14,520
agency s Oh , it's not for us . What I 

1283
00:58:14,520 --> 00:58:17,350
can say is there will be ample amount 

1284
00:58:17,350 --> 00:58:19,580
of vaccine available to immunize three 

1285
00:58:19,580 --> 00:58:21,420
million such residents 

1286
00:58:23,330 --> 00:58:25,760
by the end of the month of December . 

1287
00:58:27,230 --> 00:58:29,230
Thank you , Dr Slowly , Thank you , 

1288
00:58:29,230 --> 00:58:31,397
General Purna . And thanks to everyone 

1289
00:58:31,397 --> 00:58:33,452
for joining , that's all the time we 

1290
00:58:33,452 --> 00:58:35,508
have for today . Again . Please send 

1291
00:58:35,508 --> 00:58:37,452
any follow up questions to the HHS 

1292
00:58:37,452 --> 00:58:39,619
press office at media at HHS dot gov . 

1293
00:58:39,619 --> 00:58:41,619
And with that , we'll close today's 

1294
00:58:41,619 --> 00:58:40,460
briefing